What are the most valued startups in the biomarker testing market?
Explore our constantly refreshed ranking of the most valuable companies in the biomarker testing market.

In our updated market reports, you will find everything you need
The biomarker testing market includes companies working across genomics, proteomics, liquid biopsy, preventive health, microbiome analysis and precision diagnostics.
This ranking combines public market capitalizations, acquisition prices, funding-round valuations and carefully developed estimates.
We update this list every month to reflect new financing rounds, acquisitions, public-market movements and changes in company performance.
A quick summary table
| Metric | Value |
|---|---|
| Most valuable biomarker testing company | Natera, $38.8B |
| Second most valuable biomarker testing company | Guardant Health, $20.5B |
| Median biomarker testing valuation | Approximately $240M |
| Share of biomarker testing value captured by the top 10 | Approximately 72% |
| Top biomarker testing valuation vs. median | Approximately 162 times |
| Median valuation-to-capital-raised ratio | Approximately 2.7 times |
| Biomarker testing companies valued at $1B+ | 23 |
Top startups in the biomarker testing market ranked by valuation
Here is an updated table that ranks the top startups in the biomarker testing market based on their latest reported or estimated valuations.
| # | Startup Name | What They Do | Current Valuation ($) | Valuation Confidence Level | Valuation Type | Evidence Status | Total Funding ($) | Funding Confidence Level |
|---|---|---|---|---|---|---|---|---|
| 1 | Natera | Cell-free DNA testing | $38.8B | Full Confidence | Public Market Cap | Observed | $134M | Partial Confidence |
| 2 | Guardant Health | Liquid biopsy cancer testing | $20.5B | Full Confidence | Public Market Cap | Observed | $552M | Strong Confidence |
| 3 | Tempus AI | AI precision medicine platform | $10.2B | Full Confidence | Public Market Cap | Observed | $1.1B | Partial Confidence |
| 4 | BillionToOne | Molecular prenatal and cancer diagnostics | $5.3B | Full Confidence | Public Market Cap | Observed | $391M | Full Confidence |
| 5 | Foundation Medicine | Cancer genomic profiling tests | $5.3B | Strong Confidence | Acquisition Value | Observed | $97M | Full Confidence |
| 6 | Caris Life Sciences | Precision oncology molecular profiling | $4.9B | Full Confidence | Public Market Cap | Observed | $1.2B | Strong Confidence |
| 7 | Veracyte | Genomic cancer diagnostic tests | $4.8B | Full Confidence | Public Market Cap | Observed | $141M | Strong Confidence |
| 8 | Thorne HealthTech | Supplements and biomarker health testing | $3.5B–$4.0B | Strong Confidence | Revenue or ARR Multiple Estimate | Estimated | $70M | Partial Confidence |
| 9 | Color Health | Population genomics and preventive care | $2.5B–$4.0B | Partial Confidence | Comparables-Based Estimate | Estimated | $482M | Partial Confidence |
| 10 | Olink | High-throughput protein biomarker analysis | $3.1B | Full Confidence | Acquisition Value | Observed | $265M | Strong Confidence |
| 11 | GRAIL | Multi-cancer blood detection | $2.9B | Full Confidence | Public Market Cap | Observed | $2.3B | Strong Confidence |
| 12 | Function Health | Comprehensive preventive biomarker testing | $2.5B | Full Confidence | Announced Private Round Valuation | Observed | $354M | Partial Confidence |
| 13 | GeneDx | Rare-disease genomic testing | $2.1B | Full Confidence | Public Market Cap | Observed | $1.1B | Partial Confidence |
| 14 | Thrive Earlier Detection | Blood-based early cancer detection | $1.7B–$2.2B | Strong Confidence | Acquisition Value | Observed | $367M | Strong Confidence |
| 15 | Neko Health | AI-powered preventive body scans | $1.8B–$2.0B | Strong Confidence | Announced Private Round Valuation | Implied | $325M | Full Confidence |
| 16 | Alamar Biosciences | Ultrasensitive precision proteomics platform | $1.8B | Full Confidence | Public Market Cap | Observed | $429M | Full Confidence |
| 17 | CareDx | Transplant molecular diagnostic testing | $1.5B | Full Confidence | Public Market Cap | Observed | $182M | Partial Confidence |
| 18 | ArcherDX | Oncology genomic diagnostic assays | $1.4B | Strong Confidence | Acquisition Value | Observed | $150M | Full Confidence |
| 19 | Delfi Diagnostics | Fragmentomics cancer blood tests | $1.0B–$1.8B | Low Confidence | Implied Valuation from Raise | Estimated | $331M | Full Confidence |
| 20 | Burning Rock Biotech | Oncology genomic testing | $1.2B | Full Confidence | Public Market Cap | Observed | $451M | Strong Confidence |
| 21 | Freenome | Multiomics cancer blood tests | $1.0B–$1.2B | Strong Confidence | IPO or Listing Range Valuation | Observed | $1.4B | Strong Confidence |
| 22 | Helix | Population-scale genomic data platform | $800M–$1.4B | Partial Confidence | Comparables-Based Estimate | Estimated | $350M | Strong Confidence |
| 23 | Everlywell | At-home laboratory testing platform | $900M–$1.2B | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $255M | Strong Confidence |
| 24 | Harbinger Health | Bio-AI cancer detection | $700M–$1.1B | Partial Confidence | Implied Valuation from Raise | Implied | $290M | Strong Confidence |
| 25 | LetsGetChecked | At-home diagnostics and virtual care | $700M–$1.0B | Partial Confidence | Comparables-Based Estimate | Estimated | $285M | Partial Confidence |
| 26 | Karius | Infectious disease blood diagnostics | $700M–$950M | Partial Confidence | Comparables-Based Estimate | Estimated | $320M | Strong Confidence |
| 27 | Castle Biosciences | Dermatologic cancer diagnostic tests | $734M | Full Confidence | Public Market Cap | Observed | $393M | Strong Confidence |
| 28 | Ambry Genetics | Hereditary-disease genetic testing | $600M | Full Confidence | Acquisition Value | Observed | $150M | Low Confidence |
| 29 | Scipher Medicine | Precision immunology blood testing | $450M–$700M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $227M | Full Confidence |
| 30 | Myriad Genetics | Genetic precision medicine testing | $572M | Full Confidence | Public Market Cap | Observed | $188M | Partial Confidence |
| 31 | Mercy BioAnalytics | Early-cancer extracellular-vesicle tests | $390M–$740M | Strong Confidence | Implied Valuation from Raise | Implied | $100M | Partial Confidence |
| 32 | Resolution Bioscience | Liquid-biopsy genomic profiling | $550M | Strong Confidence | Acquisition Value | Observed | Not provided | Low Confidence |
| 33 | Personal Genome Diagnostics | Cancer genomic profiling tests | $450M–$575M | Partial Confidence | Acquisition Value | Observed | $200M | Partial Confidence |
| 34 | ClearNote Health | Epigenomic early-cancer blood tests | $350M–$650M | Strong Confidence | Implied Valuation from Raise | Implied | $144M | Partial Confidence |
| 35 | SOPHiA GENETICS | AI genomic interpretation platform | $488M | Full Confidence | Public Market Cap | Observed | $503M | Strong Confidence |
| 36 | Everlab | AI-powered preventive health assessments | $450M–$500M | Strong Confidence | Announced Private Round Valuation | Observed | $58M | Full Confidence |
| 37 | MiRXES | RNA-based cancer detection tests | $466M | Full Confidence | Public Market Cap | Observed | $254M | Partial Confidence |
| 38 | MedGenome | Genomic diagnostics and research services | $320M–$590M | Partial Confidence | Implied Valuation from Raise | Implied | $173M | Strong Confidence |
| 39 | ZOE | Personalized nutrition microbiome testing | $350M–$550M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $118M | Partial Confidence |
| 40 | Geneseeq | Precision-oncology genomic testing | $350M–$500M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | Not provided | Low Confidence |
| 41 | Inivata | Liquid biopsy cancer testing | $390M–$415M | Strong Confidence | Acquisition Value | Observed | $164M | Strong Confidence |
| 42 | Singlera Genomics | Methylation-based cancer detection | $300M–$500M | Partial Confidence | Comparables-Based Estimate | Estimated | $289M | Partial Confidence |
| 43 | SomaLogic | Large-scale protein biomarker measurement | $350M–$425M | Strong Confidence | Acquisition Value | Observed | $1.3B | Partial Confidence |
| 44 | Variantyx | Whole-genome clinical diagnostic testing | $250M–$400M | Partial Confidence | Implied Valuation from Raise | Estimated | $131M | Partial Confidence |
| 45 | Viome | RNA-based personalized health testing | $250M–$400M | Partial Confidence | Implied Valuation from Raise | Implied | $304M | Partial Confidence |
| 46 | 23andMe | Consumer genetics and research | $305M | Full Confidence | Acquisition Value | Observed | $1.5B | Partial Confidence |
| 47 | Epic Sciences | Circulating-tumor-cell diagnostics | $180M–$300M | Partial Confidence | Implied Valuation from Raise | Implied | $205M | Strong Confidence |
| 48 | OncoHost | Proteomic cancer treatment response testing | $180M–$300M | Partial Confidence | Implied Valuation from Raise | Implied | $43M | Full Confidence |
| 49 | Invitae | Clinical genetic testing services | $239M | Full Confidence | Acquisition Value | Observed | $207M | Partial Confidence |
| 50 | AnchorDx | Cancer methylation detection tests | $150M–$300M | Low Confidence | Comparables-Based Estimate | Estimated | $83M | Partial Confidence |
| 51 | Prenetics | Consumer genetic and health testing | $218M | Full Confidence | Public Market Cap | Observed | $560M | Strong Confidence |
| 52 | GenePlanet | Preventive consumer genetic testing | $150M–$280M | Partial Confidence | Implied Valuation from Raise | Implied | $34M | Strong Confidence |
| 53 | Biodesix | Lung-cancer blood diagnostics | $214M | Full Confidence | Public Market Cap | Observed | $289M | Partial Confidence |
| 54 | Nautilus Biotechnology | Single-molecule proteome analysis platform | $210M | Full Confidence | Public Market Cap | Observed | $449M | Strong Confidence |
| 55 | Quantum-Si | Single-molecule protein sequencing | $203M | Full Confidence | Public Market Cap | Observed | $634M | Strong Confidence |
| 56 | RareCyte | Rare-cell and spatial analysis | $130M–$250M | Partial Confidence | Implied Valuation from Raise | Implied | $96M | Partial Confidence |
| 57 | Adela | Methylome blood cancer testing | $130M–$210M | Low Confidence | Implied Valuation from Raise | Estimated | $133M | Strong Confidence |
| 58 | 4baseCare | Precision oncology genomic testing | $100M–$190M | Strong Confidence | Implied Valuation from Raise | Implied | $19M | Partial Confidence |
| 59 | PrognomiQ | Multi-omics early cancer detection | $100M–$160M | Partial Confidence | Implied Valuation from Raise | Estimated | $145M | Partial Confidence |
| 60 | Seer | Proteomic biomarker discovery platform | $123M | Full Confidence | Public Market Cap | Observed | $347M | Full Confidence |
| 61 | InsideTracker | Personalized blood biomarker optimization | $90M–$140M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $18M | Strong Confidence |
| 62 | Tethis | Automated liquid-biopsy sample processing | $80M–$140M | Partial Confidence | Implied Valuation from Raise | Implied | $15M | Partial Confidence |
| 63 | Lucence | Blood-based cancer detection | $70M–$120M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $29M | Strong Confidence |
| 64 | Predicine | Liquid-biopsy biomarker assays | $70M–$120M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $41M | Partial Confidence |
| 65 | Strand Life Sciences | Clinical genomics and bioinformatics | $93M | Strong Confidence | Acquisition Value | Implied | $35M | Partial Confidence |
| 66 | Biognosys | Proteomics services and analysis software | $80M–$85M | Strong Confidence | Acquisition Value | Implied | $8M | Partial Confidence |
| 67 | C2i Genomics | MRD cancer recurrence monitoring | $70M–$95M | Strong Confidence | Acquisition Value | Observed | $112M | Full Confidence |
| 68 | Blueprint Genetics | Rare-disease genetic diagnostic testing | $60M–$100M | Low Confidence | Comparables-Based Estimate | Estimated | $26M | Partial Confidence |
| 69 | NIPD Genetics | Prenatal and cancer genetic tests | $74M | Strong Confidence | Acquisition Value | Observed | Not provided | Low Confidence |
| 70 | Nightingale Health | Blood-based metabolic biomarker profiling | $60M | Full Confidence | Public Market Cap | Observed | $154M | Partial Confidence |
| 71 | Sysmex Inostics | Ultra-sensitive liquid-biopsy assays | $40M–$80M | Low Confidence | Acquisition Value | Estimated | Not provided | Low Confidence |
| 72 | Tiny Health | Infant and maternal microbiome testing | $45M–$75M | Partial Confidence | Implied Valuation from Raise | Implied | $13M | Full Confidence |
| 73 | Veritas Genetics | Whole-genome consumer testing | $40M–$80M | Low Confidence | Proxy-Based Estimate | Estimated | $53M | Strong Confidence |
| 74 | GlycanAge | Glycan-based biological age testing | $45M–$70M | Partial Confidence | Implied Valuation from Raise | Implied | $13M | Full Confidence |
| 75 | Genomic Life | Genomics-based health navigation | $40M–$67M | Partial Confidence | Implied Valuation from Raise | Implied | $10M | Low Confidence |
| 76 | Fabric Genomics | AI genomic interpretation software | $51M | Full Confidence | Acquisition Value | Observed | $30M | Full Confidence |
| 77 | CircleDNA | Consumer DNA testing services | $30M–$55M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $15M | Partial Confidence |
| 78 | GenomOncology | Precision oncology interpretation software | $30M–$55M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $6M | Partial Confidence |
| 79 | Dxcover | Spectroscopic cancer blood testing | $32M–$45M | Strong Confidence | Implied Valuation from Raise | Implied | $19M | Partial Confidence |
| 80 | TruDiagnostic | Epigenetic biological age diagnostics | $25M–$45M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | Not provided | Low Confidence |
| 81 | Congenica | Clinical genome interpretation software | $20M–$40M | Low Confidence | Comparables-Based Estimate | Estimated | $81M | Strong Confidence |
| 82 | Jona | AI microbiome health insights | $20M–$35M | Partial Confidence | Implied Valuation from Raise | Implied | $5M | Full Confidence |
| 83 | Tally Health | Consumer biological age testing | $15M–$35M | Low Confidence | Acquisition Value | Estimated | $10M | Full Confidence |
| 84 | Chronix Biomedical | Blood-based cancer monitoring | $24M | Strong Confidence | Acquisition Value | Observed | $22M | Low Confidence |
| 85 | Ombre | Microbiome testing and probiotics | $18M–$30M | Low Confidence | Comparables-Based Estimate | Estimated | $10M | Partial Confidence |
| 86 | CosmosID | Metagenomics testing and bioinformatics | $15M–$30M | Low Confidence | Comparables-Based Estimate | Estimated | $7M | Partial Confidence |
| 87 | Sun Genomics | Personalized probiotics and microbiome testing | $15M–$25M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $12M | Partial Confidence |
| 88 | Mapmygenome | Personal genomics and diagnostics | $10M–$25M | Low Confidence | Proxy-Based Estimate | Estimated | $2M | Low Confidence |
| 89 | Microba Life Sciences | Clinical microbiome testing and therapeutics | $16M | Full Confidence | Public Market Cap | Observed | $52M | Strong Confidence |
| 90 | Exosome Diagnostics | Exosome-based prostate cancer testing | $15M | Full Confidence | Acquisition Value | Observed | $119M | Strong Confidence |
| 91 | Immunovia | Pancreatic cancer blood testing | $14M | Full Confidence | Public Market Cap | Observed | $64M | Partial Confidence |
| 92 | ANGLE | Parsortix liquid-biopsy systems | $9M–$11M | Strong Confidence | Public Market Cap | Observed | $65M | Partial Confidence |
| 93 | DayTwo | Microbiome-based glycemic nutrition | $0M–$2M | Strong Confidence | Proxy-Based Estimate | Estimated | $85M | Strong Confidence |
| 94 | Encodia | DNA-encoded protein sequencing technology | $0M–$2M | Low Confidence | Proxy-Based Estimate | Estimated | $79M | Partial Confidence |
| 95 | Progenity | Former prenatal molecular diagnostics company | $0M–$2M | Low Confidence | Proxy-Based Estimate | Estimated | $237M | Partial Confidence |
| 96 | Biocept | Liquid-biopsy cancer assays | $0M | Full Confidence | Acquisition Value | Observed | $59M | Partial Confidence |
Key valuation trends in the biomarker testing market
Insights
- The biomarker testing market is highly concentrated. The top 10 companies represent about 72% of the combined valuation in this ranking, while the remaining 86 companies share less than 30%.
- Natera and Guardant Health alone account for approximately $59.3 billion of value. This is more than 40% of the estimated value of every biomarker testing company in the dataset.
- Foundation Medicine reached a $5.3 billion acquisition value after raising only $97 million. The resulting ratio of almost 55 times shows the strategic value of validated cancer genomic testing assets.
- Guardant Health is valued at roughly 37 times its reported funding, while Veracyte is valued at approximately 34 times funding. Commercial adoption can create substantial capital efficiency in clinical diagnostics.
- GRAIL presents a different pattern. GRAIL raised approximately $2.3 billion, but its $2.9 billion market capitalization represents only about 1.3 times the capital invested.
- Freenome, Quantum-Si, Nautilus Biotechnology and Seer raised approximately $2.8 billion combined, but their combined valuations total only about $1.6 billion. Development-heavy biomarker platforms can require significant capital before achieving commercial scale.
- Olink generated a $3.1 billion acquisition value from approximately $265 million of funding. The transaction suggests strategic buyers may pay substantial premiums for differentiated proteomics infrastructure.
- Preventive biomarker testing is beginning to attract valuations previously associated with clinical oncology. Function Health, Neko Health and Everlab have a combined estimated value of almost $4.9 billion.
- Microbiome-focused companies remain much smaller than genomic and oncology diagnostics businesses. Microba Life Sciences, DayTwo and several consumer microbiome platforms are valued below the capital invested in their development.
- The median company in this biomarker testing ranking is worth approximately $240 million, while Natera is worth about 162 times that amount. The gap highlights the market’s unusually wide valuation distribution.
A few word about our methodology
As you can see, we built a database that ranks companies in the biomarker testing market based on their current valuation.
Estimating biomarker testing company valuations is not always straightforward. Many private companies do not publicly disclose their valuation, and the available information can vary widely depending on the company and its stage.
To build this ranking, we applied a structured valuation methodology and cross-checked information across multiple reliable sources.
Whenever possible, we relied on direct disclosures. These include announced valuations from completed funding rounds, public filings for listed biomarker testing companies, or official acquisition prices.
When a biomarker testing company is publicly listed, we use its current market capitalization as the reference valuation.
If a company was acquired and no independent valuation can reasonably be estimated today, we use the acquisition price as the main reference point.
When a biomarker testing startup recently raised capital but the valuation was not disclosed, we estimate the implied valuation using typical dilution levels for that stage of fundraising.
In some cases, we estimate valuations using operating metrics such as revenue, recurring revenue, testing volume or commercial adoption. We combine these indicators with valuation multiples from comparable diagnostics and life sciences companies.
When direct financial data is not available, we may rely on carefully selected comparable companies and other signals such as clinical validation, regulatory progress, reimbursement coverage, hiring growth, investor quality or product traction.
All estimates follow a strict evidence hierarchy. Recent funding rounds with announced valuations carry the most weight, followed by public-market data, acquisition prices, operating metrics and comparable company analysis.
We also carefully evaluate the age of every data point. Recent information carries more weight, while older biomarker testing data is treated cautiously and adjusted conservatively when necessary.
Whenever information is uncertain or incomplete, we clearly distinguish between confirmed facts and reasonable inferences.
Because valuation data is not always fully public, each company in the ranking is assigned a confidence level based on the reliability, recency and consistency of the available evidence.
Full confidence means the valuation is supported by strong and recent evidence. Strong confidence means the estimate is well supported but includes minor inference. Partial confidence means the estimate relies more heavily on indirect signals. Low confidence means available information is limited or inconsistent.
When confidence is lower, we take a more conservative approach by widening the valuation range. This helps reflect the uncertainty and increases the probability that the true valuation falls within the estimated range.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific valuation estimate, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.
Related blog posts
- The main fundraising trends in the biomarker testing market
- The startups that have raised the most funding in the biomarker testing market
- How healthy is startup funding in the biomarker testing market right now?
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