Which startups have raised the most funding in the regenerative medicine market?

Last updated: 13 July 2026

market research pitch 2026

In our updated market reports, you will find everything you need

The regenerative medicine market is led by cell therapy, gene therapy, genome editing, and immune-cell engineering companies that require large amounts of capital.

This list ranks regenerative medicine startups by cumulative funding raised, and we update it every month to keep the dataset fresh.

Public market financing is especially important in this market, with many leading companies relying on IPOs, follow-ons, PIPEs, and registered offerings.

A quick summary table

Metric Value
Most funded startup Genetix Biotherapeutics, $2.5B raised
Second most funded startup Lyell Immunopharma, $1.6B raised
Largest funding round Fate Therapeutics, $432M public offering
Median funding About $361.5M
Share of funding captured by the top 10 About 30.6%
Median time since last round About 29 months
Startups that raised funding in the last 12 months 26 startups
Regenerative medicine startups above $1B raised 8 startups
Cell and gene therapy startups still active 38 startups
Regenerative medicine IPO-stage companies 45 startups

Top startups in the regenerative medicine market ranked by total funding raised

Here is an updated table that ranks the top startups in the regenerative medicine market based on the total amount of funding they have raised to date.

The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected (we excluded startups with very low data confidence, to make sure everything is reliable).

# Startup What They Do Total Raised ($) Total Rounds Last Round Date Last Round Amount ($) Last Round Type Key Investors Current Stage Confidence
1 Genetix Biotherapeutics Approved rare-disease gene therapies $2.5B 10 December 2023 $150M Public Offering Carlyle, SK Capital, Third Rock Acquired Partial
2 Lyell Immunopharma Reprograms T cells $1.6B 6 July 2025 $100M Private placement GSK, Perceptive Advisors, Foresite Capital IPO Strong
3 Sana Biotechnology Engineers cells as medicines $1.4B 6 August 2025 $75M Public offering ARCH Venture Partners, Flagship Pioneering, F-Prime Capital IPO Strong
4 Legend Biotech Develops CAR-T therapies $1.3B 5 June 2026 $226M Public offering Morgan Stanley, Jefferies, Citi IPO Strong
5 ElevateBio Cell and gene therapy platform $1.2B 4 May 2023 $401M Series D Matrix Capital, Woodline, Novo Nordisk Active Full
6 Fate Therapeutics iPSC-derived cell immunotherapies $1.1B 9 January 2021 $432M Public offering Public investors IPO Strong
7 Allogene Therapeutics Off-the-shelf CAR-T therapies $1.1B 4 April 2026 $200M Public offering TPG, Vida Ventures, Goldman Sachs IPO Partial
8 Iovance Biotherapeutics Tumor-infiltrating lymphocyte therapies $1.1B 6 February 2024 $211M Public offering OrbiMed, Goldman Sachs, Jefferies IPO Partial
9 Maze Therapeutics Small-molecule precision medicines $936M 6 April 2026 $150M Registered Offering Farallon Capital Management, T. Rowe Price, existing investors IPO Strong
10 Kriya Therapeutics Gene therapies for chronic diseases $914M 5 August 2025 $313M Series D / Equity Financing Patient Square, Foresite, Woodline Active Strong
11 Century Therapeutics iPSC allogeneic cell therapies $848M 5 January 2026 $135M Private placement TCGX, RA Capital, Commodore Capital IPO Strong
12 uniQure AAV gene therapy developer $744M 5+ July 2026 $225M Public Offering Gilde Healthcare, Jefferies, Leerink IPO Partial
13 Instil Bio Cell therapies for oncology $739M 4 March 2021 $368M IPO CPMG, public investors IPO Strong
14 Autolus Therapeutics Programmed T-cell therapies $688M 5 February 2024 $350M Public offering Syncona, Woodford, Nextech Invest IPO Strong
15 Artiva Biotherapeutics Allogeneic NK cell therapies $677M 4 May 2026 $300M Public offering Blackstone, RA Capital, RTW Investments IPO Strong
16 CARsgen Therapeutics CAR-T cancer therapies $676M 4 June 2021 $400M IPO Loyal Valley Capital, Lilly Asia Ventures, public investors IPO Strong
17 Kite Pharma CAR-T cancer therapies $635M 6 March 2017 $410M Follow-on offering Alta Partners, Pontifax, Public investors Acquired Strong
18 Editas Medicine CRISPR genome-editing medicines $632M 5 May 2026 $125M Public Offering Flagship, Polaris, Third Rock IPO Strong
19 ArsenalBio Programmable solid-tumor CAR-T $630M 3 September 2024 $325M Series C ARCH Venture Partners, Regeneron Ventures, NVentures Active Full
20 Tessera Therapeutics Gene writing therapeutics $610M 3 April 2022 $300M+ Series C Alaska Permanent Fund, ADIA, Flagship Pioneering Active Partial
21 Nkarta Therapeutics Engineered NK cell therapies $606M 3 March 2024 $240M Public equity offering Adage Capital, Boxer Capital, RA Capital IPO Strong
22 Mesoblast Cell therapies for inflammation $600M+ 13+ 2025 Undisclosed Post-IPO equity Institutional investors IPO Partial
23 Passage Bio CNS gene therapies $596M 4 January 2021 $154M Follow-on public offering OrbiMed, Access Biotechnology, Versant Ventures IPO Full
24 Taysha Gene Therapies CNS gene therapies $532M 5 June 2024 $75M Public Offering Institutional investors, Goldman Sachs, Jefferies IPO Strong
25 Gracell Biotechnologies FasTCAR cell therapies $494M 4 August 2023 $100M PIPE Healthcare specialist investors Acquired Strong
26 Caribou Biosciences CRISPR allogeneic cell therapies $490M 3 June 2023 $25M Strategic equity investment Pfizer, Farallon Capital, PFM Health Sciences IPO Partial
27 JW Therapeutics China CAR-T cell therapies $490M 3 November 2020 $300M IPO Public investors IPO Full
28 Kyverna Therapeutics Autoimmune CAR-T therapies $489M 4 February 2024 $319M IPO Northpond Ventures, Bain Capital Life Sciences, Gilead Sciences IPO Full
29 Verve Therapeutics Cardiovascular gene editing $482M 4 June 2021 $267M IPO GV, Wellington Management, Casdin Capital Acquired Full
30 CARGO Therapeutics CAR-T relapse therapies $481M 2 November 2023 $281M IPO Public investors Acquired Full
31 4D Molecular Therapeutics AAV gene medicines $480M 8 November 2025 $100M Public Offering Leerink Partners, Evercore ISI, Cantor IPO Partial
32 Neurogene Neurological gene therapies $479M 4 November 2024 $200M Private Placement EcoR1 Capital, Redmile Group, Samsara BioCapital IPO Strong
33 Celularity Placenta-derived cell therapies $478M 4 December 2025 $10M Convertible notes Philip A. Barach IPO Partial
34 Arcellx Cell therapy for myeloma $466M 6 February 2023 $100M Post-IPO offering NEA, Novo Holdings, Samsara BioCapital Acquired Strong
35 Generation Bio Non-viral genetic medicines $465M 4 June 2020 $230M IPO Atlas Venture, Fidelity, T. Rowe Price IPO Full
36 Spark Therapeutics Rare-disease gene therapies $465M 4 December 2015 $181M Follow-on Offering CHOP, Sofinnova, Deerfield Acquired Full
37 TScan Therapeutics TCR-T cancer cell therapies $463M 6 December 2024 $30M Registered direct offering Lynx1 Capital, BlackRock, RA Capital IPO Strong
38 Poseida Therapeutics Nonviral cell and gene therapies $452M 5 August 2023 $25M Strategic equity investment Astellas, Novartis, Longitude Capital Acquired Strong
39 Cellectis Gene-edited allogeneic CAR-T $448M 3 May 2024 $140M Strategic equity investment AstraZeneca IPO Partial
40 Freeline Therapeutics Systemic AAV gene therapies $434M 4 August 2020 $159M IPO Syncona, Novo Holdings, Eventide Asset Management Acquired Strong
41 Metagenomi Gene editing medicines $434M 4 February 2024 $94M IPO Leaps by Bayer, Novo Holdings, Catalio Capital IPO Full
42 Vor Biopharma Engineered stem-cell therapies $429M 5 November 2025 $100M Public offering RA Capital, 5AM Ventures, Fidelity IPO Strong
43 Cabaletta Bio Autoimmune CAR-T therapies $426M 6 May 2026 $150M Public offering Bain Capital, Adage, Cormorant IPO Strong
44 Lexeo Therapeutics Cardiovascular gene therapies $420M 4 October 2025 $135M Public offering / private placement Longitude Capital, Omega Funds, Eventide Asset Management IPO Full
45 Immatics TCR cancer immunotherapies $415M+ 4 July 2023 $35M Strategic equity investment Bristol Myers Squibb, Perceptive Advisors, Wellington Partners IPO Partial
46 Korro Bio RNA editing medicines $410M 4 March 2026 $85M PIPE Wu Capital, Eventide Asset Management, Venrock IPO Full
47 Voyager Therapeutics Neurogenetic medicines $368M 6 January 2024 $100M Public offering Third Rock Ventures, Novartis, Wellington Management IPO Strong
48 Umoja Biopharma In vivo CAR-T therapies $363M 3 January 2025 $100M Series C Double Point, DCVC Bio, ARK Invest Active Strong
49 AvenCell Therapeutics Switchable CAR-T therapies $362M 2 October 2024 $112M Series B Novo Holdings, F-Prime Capital, Piper Heartland Active Full
50 Senti Biosciences Programmable cell therapies $362M 4 January 2025 $48M PIPE Celadon Partners, NEA, Leaps by Bayer IPO Full
51 Precision BioSciences ARCUS gene editing $361M 6 November 2025 $75M Public Offering Aberdeen Investments, Driehaus Capital, Sphera Funds IPO Strong
52 OriCell Therapeutics Solid-tumor CAR-T therapies $350M+ 4 April 2026 $110M+ Pre-IPO Vivo Capital, Qiming Venture Partners, Beijing Medical Fund Active Strong
53 Capstan Therapeutics In vivo cell engineering $340M 3 March 2024 $175M Series B RA Capital, Forbion, JJDC Acquired Full
54 Aspen Neuroscience Autologous neuron replacement $339M 4 November 2025 $115M Series C OrbiMed, ARCH Venture Partners, Frazier Life Sciences Active Full
55 Sonoma Biotherapeutics Treg cell therapies $335M 3 August 2021 $265M Series B Ally Bridge Group, Deep Track Capital, Fidelity Active Full
56 Obsidian Therapeutics Engineered TIL therapies $325M 3 April 2024 $161M Series C Wellington Management, Foresite Capital, Novo Holdings Active Full
57 Wugen Off-the-shelf CAR-T $323M 4 August 2025 $115M Series C Fidelity Management, RiverVest, Lightchain Capital Active Partial
58 Arbor Biotechnologies Gene editing therapeutics $305M 3 March 2025 $74M Series C ARCH Venture Partners, TCGX, Temasek Active Partial
59 IASO Biotherapeutics CAR-T cell therapies $303M 4 September 2025 $60M Series C extension GL Ventures, CDH Baifu, Guoxin Active Partial
60 Adaptimmune Therapeutics TCR-T cancer therapies $295M 2 May 2015 $191M IPO Public investors IPO Strong
61 Beacon Therapeutics Ophthalmic gene therapies $289M 2 July 2024 $170M Series B Syncona, Forbion, Oxford Science Enterprises Active Full
62 Atara Biotherapeutics Off-the-shelf T-cell therapies $282M 3 December 2020 $175M Public equity offering Celgene, EcoR1, Kleiner Perkins IPO Partial
63 A2 Biotherapeutics Logic-gated CAR-T $271M 5 January 2025 $80M Series C The Column Group, Samsara BioCapital, Vida Ventures Active Partial
64 Acepodia Allogeneic cell cancer therapies $266M 4 June 2023 $100M Series D Digital Mobile Venture, Ridgeback Capital, 8VC Active Strong
65 Quell Therapeutics Engineered Treg cell therapies $265M 4 January 2023 $24M Series B extension Syncona, Janus Henderson, Monashee Active Partial
66 AIRNA RNA editing therapeutics $245M 3 April 2025 $155M Series B ARCH Venture Partners, Forbion, Venrock Active Full
67 Adicet Bio Gamma delta T-cell therapies $244M 4 January 2024 $98M Public follow-on OrbiMed, RA Capital, Novartis Venture Fund IPO Partial
68 AbelZeta Pharma T-cell cancer therapies $240M 8 September 2021 $120M Series A Sequoia Capital, AstraZeneca-CICC, Yunfeng Capital Active Partial
69 Atsena Therapeutics Ocular gene therapies $238M 4 April 2025 $150M Series C Bain Capital, Sofinnova, Hatteras Active Strong
70 Asklepios BioPharmaceutical AAV gene therapy platform $235M 1 April 2019 $235M Private equity TPG Capital, Vida Ventures, founders Acquired Partial
71 Capricor Therapeutics Cell exosome rare-disease therapies $230M 7 December 2025 $150M Public offering Public investors IPO Partial
72 BlueRock Therapeutics iPSC-derived cell therapies $225M 1 December 2016 $225M Series A Bayer, Versant Ventures, Leaps by Bayer Acquired Full
73 Affini-T Therapeutics TCR therapies for tumors $193M 2 October 2024 $18M Series A-II Vida Ventures, Leaps by Bayer, Humboldt Fund Active Strong
74 Celyad Oncology CAR-T oncology therapies $192M 4 December 2021 $33M Private placement Fortress Investment Group, public investors IPO Partial
75 Gamida Cell Stem cell transplant therapies $189M 4 October 2018 $50M IPO Shavit Capital, Novartis, Clal Biotechnology Acquired Partial
76 T-knife Therapeutics TCR-T solid tumor therapies $188M 2 August 2021 $110M Series B Fidelity, LSP, Qatar Investment Authority Active Full
77 Shoreline Biosciences iPSC NK cell therapies $183M 2 November 2021 $140M Series B Ally Bridge Group, BeiGene, Eventide Active Full
78 GentiBio Engineered Treg cell therapies $177M 2 August 2021 $157M Series A Matrix Capital, Avidity Partners, JDRF T1D Fund Active Full
79 CRISPR Therapeutics CRISPR gene editing $145M 3 October 2016 $56M IPO Versant Ventures, SR One, Celgene IPO Partial
80 Interius BioTherapeutics In vivo CAR therapeutics $145M 3 August 2024 $67M Series B Cormorant, Fairmount, Bain Capital Life Sciences Acquired Strong
81 EXUMA Biotech Gene-delivered cell therapies $130M 4 December 2021 $41M Series B2 MSD Partners, F1 BioVentures, Sinobioway Active Partial
82 ImmPACT Bio Logic-gated CAR-T therapies $129M 2 January 2022 $111M Series B venBio, Foresite Capital, Decheng Capital Active Strong
83 Curocell Korean CAR-T therapies $107M 7 November 2023 $24M IPO Aju IB, IMM Investment, STIC Ventures IPO Partial
84 Bioheng Therapeutics Allogeneic CAR-T cell therapies $105M 4 June 2022 $7M Series B / extension Zhengxuan Investment, Decheng Capital, GL Ventures Active Partial
85 Juventas Cell Therapy China CAR-T therapies $101M 3 July 2021 $63M Series C CICC Capital, Oceanpine, Delian Capital Active Strong
86 Triumvira Immunologics Engineered TAC-T cancer therapies $100M 2 March 2022 $45M Series A extension B Capital Group, Northpond Ventures, Bloom Burton Active Strong
87 Indapta Therapeutics Allogeneic NK cell therapies $90M 2 December 2024 $23M Undisclosed equity Leaps by Bayer, Myeloma Investment Fund, Pontifax Active Partial
88 Sangamo Therapeutics Genomic medicine platform $77M 2 March 2024 $24M Registered Direct Institutional investors, placement agents IPO Low
89 Tr1X Allogeneic Treg cell therapies $75M 1 January 2024 $75M Series A The Column Group, NEVA SGR, Alexandria Ventures Active Full
90 Verismo Therapeutics KIR-CAR cell therapies $68M 4 April 2026 $28M Undisclosed equity HLB Innovation Active Strong
91 Inceptor Bio CAR cell therapy platforms $58M 2 February 2025 $21M Series A2 Kineticos Life Sciences Active Strong
92 Immuneel Therapeutics Affordable CAR-T cancer therapies $53M 4 June 2026 $11M Series B Singularity AMC, Rainmatter, Eight Roads Ventures Active Partial
93 Kelonia Therapeutics In vivo CAR-T platform $50M 1 April 2022 $50M Series A Alta Partners, Horizons Ventures, Venrock Active Full
94 MiNK Therapeutics Off-the-shelf iNKT therapies $46M 2 May 2024 $6M PIPE GKCC, public investors IPO Strong
95 Noile-Immune Biotech PRIME CAR-T cancer therapies $43M 3 June 2023 $22M IPO Dai-ichi Life, Binex, BiGEN IPO Partial
96 Catamaran Bio Off-the-shelf CAR-NK therapies $42M 1 November 2020 $42M Series A Sofinnova, Lightstone, SV Health Shutdown Full
97 Chimeric Therapeutics CAR-T and NK therapies $40M 6 December 2025 $3M Placement Bell Potter, Baker Young, L1 Capital IPO Partial
98 AffyImmune Therapeutics Tuned solid-tumor CAR-T $38M 2 October 2021 $30M Series A+ ORI Capital Active Partial
99 PeproMene Bio BAFF-R CAR-T therapies $33M 2 June 2018 $29M Series B Not disclosed Active Low
100 Invectys HLA-G cancer immunotherapies $31M 4 October 2018 $17M Series A Undisclosed family office, Bpifrance Active Low

Key funding trends in the regenerative medicine market

Insights

  • The top 10 regenerative medicine startups raised about $13.15B, or roughly 30.6% of the full ranking, showing strong funding concentration around a small group of leaders.
  • Cell therapy and CAR-T companies dominate the upper part of the ranking, which suggests investors continue to favor immune-cell engineering platforms with oncology applications.
  • Public market financing remains a major funding engine in regenerative medicine, since many leaders reached large totals through IPOs, follow-ons, PIPEs, and registered offerings.
  • Active private companies such as ElevateBio, Kriya Therapeutics, ArsenalBio, Aspen Neuroscience, Obsidian Therapeutics, and Beacon Therapeutics show that growth capital is still available for differentiated platforms.
  • Gene therapy remains one of the deepest funding categories, with Kriya, Taysha, Spark, Passage Bio, Freeline, Voyager, and other AAV or genetic medicine companies raising large cumulative totals.
  • Autoimmune cell therapy is becoming a serious capital theme, with Kyverna, Cabaletta, Tr1X, Sonoma, GentiBio, and Quell showing investor interest beyond cancer treatment.
  • Large later-stage private rounds are common in regenerative medicine, especially when platforms combine strong biology, manufacturing depth, and a clear clinical path.
  • Strategic pharma participation is visible across the market, with GSK, Gilead, Pfizer, Astellas, Novartis, Bristol Myers Squibb, Bayer, and Novo Nordisk appearing as funders.

A few word about our methodology

As you can see, we built a database that ranks regenerative medicine startups based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.

Whenever possible, we prioritized official company communications, since they are the most reliable source for funding amounts. When those were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times or Forbes (to name a few).

We excluded random blogs, unverified websites, and any sources that could not be validated.

When funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.

Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.

Here is what they mean.

Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.

Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.

Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.

Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.

When the confidence level is too low, we take a conservative approach and exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.

In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.

If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.

Finally, know that we update the dataset once per month, so come back here if you need fresh information.

Who is the author of this content?

NEW MARKET PITCH TEAM

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