Which startups have raised the most funding in the regenerative medicine market?

In our updated market reports, you will find everything you need
The regenerative medicine market is led by cell therapy, gene therapy, genome editing, and immune-cell engineering companies that require large amounts of capital.
This list ranks regenerative medicine startups by cumulative funding raised, and we update it every month to keep the dataset fresh.
Public market financing is especially important in this market, with many leading companies relying on IPOs, follow-ons, PIPEs, and registered offerings.
A quick summary table
| Metric | Value |
|---|---|
| Most funded startup | Genetix Biotherapeutics, $2.5B raised |
| Second most funded startup | Lyell Immunopharma, $1.6B raised |
| Largest funding round | Fate Therapeutics, $432M public offering |
| Median funding | About $361.5M |
| Share of funding captured by the top 10 | About 30.6% |
| Median time since last round | About 29 months |
| Startups that raised funding in the last 12 months | 26 startups |
| Regenerative medicine startups above $1B raised | 8 startups |
| Cell and gene therapy startups still active | 38 startups |
| Regenerative medicine IPO-stage companies | 45 startups |
Top startups in the regenerative medicine market ranked by total funding raised
Here is an updated table that ranks the top startups in the regenerative medicine market based on the total amount of funding they have raised to date.
The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected (we excluded startups with very low data confidence, to make sure everything is reliable).
| # | Startup | What They Do | Total Raised ($) | Total Rounds | Last Round Date | Last Round Amount ($) | Last Round Type | Key Investors | Current Stage | Confidence |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Genetix Biotherapeutics | Approved rare-disease gene therapies | $2.5B | 10 | December 2023 | $150M | Public Offering | Carlyle, SK Capital, Third Rock | Acquired | Partial |
| 2 | Lyell Immunopharma | Reprograms T cells | $1.6B | 6 | July 2025 | $100M | Private placement | GSK, Perceptive Advisors, Foresite Capital | IPO | Strong |
| 3 | Sana Biotechnology | Engineers cells as medicines | $1.4B | 6 | August 2025 | $75M | Public offering | ARCH Venture Partners, Flagship Pioneering, F-Prime Capital | IPO | Strong |
| 4 | Legend Biotech | Develops CAR-T therapies | $1.3B | 5 | June 2026 | $226M | Public offering | Morgan Stanley, Jefferies, Citi | IPO | Strong |
| 5 | ElevateBio | Cell and gene therapy platform | $1.2B | 4 | May 2023 | $401M | Series D | Matrix Capital, Woodline, Novo Nordisk | Active | Full |
| 6 | Fate Therapeutics | iPSC-derived cell immunotherapies | $1.1B | 9 | January 2021 | $432M | Public offering | Public investors | IPO | Strong |
| 7 | Allogene Therapeutics | Off-the-shelf CAR-T therapies | $1.1B | 4 | April 2026 | $200M | Public offering | TPG, Vida Ventures, Goldman Sachs | IPO | Partial |
| 8 | Iovance Biotherapeutics | Tumor-infiltrating lymphocyte therapies | $1.1B | 6 | February 2024 | $211M | Public offering | OrbiMed, Goldman Sachs, Jefferies | IPO | Partial |
| 9 | Maze Therapeutics | Small-molecule precision medicines | $936M | 6 | April 2026 | $150M | Registered Offering | Farallon Capital Management, T. Rowe Price, existing investors | IPO | Strong |
| 10 | Kriya Therapeutics | Gene therapies for chronic diseases | $914M | 5 | August 2025 | $313M | Series D / Equity Financing | Patient Square, Foresite, Woodline | Active | Strong |
| 11 | Century Therapeutics | iPSC allogeneic cell therapies | $848M | 5 | January 2026 | $135M | Private placement | TCGX, RA Capital, Commodore Capital | IPO | Strong |
| 12 | uniQure | AAV gene therapy developer | $744M | 5+ | July 2026 | $225M | Public Offering | Gilde Healthcare, Jefferies, Leerink | IPO | Partial |
| 13 | Instil Bio | Cell therapies for oncology | $739M | 4 | March 2021 | $368M | IPO | CPMG, public investors | IPO | Strong |
| 14 | Autolus Therapeutics | Programmed T-cell therapies | $688M | 5 | February 2024 | $350M | Public offering | Syncona, Woodford, Nextech Invest | IPO | Strong |
| 15 | Artiva Biotherapeutics | Allogeneic NK cell therapies | $677M | 4 | May 2026 | $300M | Public offering | Blackstone, RA Capital, RTW Investments | IPO | Strong |
| 16 | CARsgen Therapeutics | CAR-T cancer therapies | $676M | 4 | June 2021 | $400M | IPO | Loyal Valley Capital, Lilly Asia Ventures, public investors | IPO | Strong |
| 17 | Kite Pharma | CAR-T cancer therapies | $635M | 6 | March 2017 | $410M | Follow-on offering | Alta Partners, Pontifax, Public investors | Acquired | Strong |
| 18 | Editas Medicine | CRISPR genome-editing medicines | $632M | 5 | May 2026 | $125M | Public Offering | Flagship, Polaris, Third Rock | IPO | Strong |
| 19 | ArsenalBio | Programmable solid-tumor CAR-T | $630M | 3 | September 2024 | $325M | Series C | ARCH Venture Partners, Regeneron Ventures, NVentures | Active | Full |
| 20 | Tessera Therapeutics | Gene writing therapeutics | $610M | 3 | April 2022 | $300M+ | Series C | Alaska Permanent Fund, ADIA, Flagship Pioneering | Active | Partial |
| 21 | Nkarta Therapeutics | Engineered NK cell therapies | $606M | 3 | March 2024 | $240M | Public equity offering | Adage Capital, Boxer Capital, RA Capital | IPO | Strong |
| 22 | Mesoblast | Cell therapies for inflammation | $600M+ | 13+ | 2025 | Undisclosed | Post-IPO equity | Institutional investors | IPO | Partial |
| 23 | Passage Bio | CNS gene therapies | $596M | 4 | January 2021 | $154M | Follow-on public offering | OrbiMed, Access Biotechnology, Versant Ventures | IPO | Full |
| 24 | Taysha Gene Therapies | CNS gene therapies | $532M | 5 | June 2024 | $75M | Public Offering | Institutional investors, Goldman Sachs, Jefferies | IPO | Strong |
| 25 | Gracell Biotechnologies | FasTCAR cell therapies | $494M | 4 | August 2023 | $100M | PIPE | Healthcare specialist investors | Acquired | Strong |
| 26 | Caribou Biosciences | CRISPR allogeneic cell therapies | $490M | 3 | June 2023 | $25M | Strategic equity investment | Pfizer, Farallon Capital, PFM Health Sciences | IPO | Partial |
| 27 | JW Therapeutics | China CAR-T cell therapies | $490M | 3 | November 2020 | $300M | IPO | Public investors | IPO | Full |
| 28 | Kyverna Therapeutics | Autoimmune CAR-T therapies | $489M | 4 | February 2024 | $319M | IPO | Northpond Ventures, Bain Capital Life Sciences, Gilead Sciences | IPO | Full |
| 29 | Verve Therapeutics | Cardiovascular gene editing | $482M | 4 | June 2021 | $267M | IPO | GV, Wellington Management, Casdin Capital | Acquired | Full |
| 30 | CARGO Therapeutics | CAR-T relapse therapies | $481M | 2 | November 2023 | $281M | IPO | Public investors | Acquired | Full |
| 31 | 4D Molecular Therapeutics | AAV gene medicines | $480M | 8 | November 2025 | $100M | Public Offering | Leerink Partners, Evercore ISI, Cantor | IPO | Partial |
| 32 | Neurogene | Neurological gene therapies | $479M | 4 | November 2024 | $200M | Private Placement | EcoR1 Capital, Redmile Group, Samsara BioCapital | IPO | Strong |
| 33 | Celularity | Placenta-derived cell therapies | $478M | 4 | December 2025 | $10M | Convertible notes | Philip A. Barach | IPO | Partial |
| 34 | Arcellx | Cell therapy for myeloma | $466M | 6 | February 2023 | $100M | Post-IPO offering | NEA, Novo Holdings, Samsara BioCapital | Acquired | Strong |
| 35 | Generation Bio | Non-viral genetic medicines | $465M | 4 | June 2020 | $230M | IPO | Atlas Venture, Fidelity, T. Rowe Price | IPO | Full |
| 36 | Spark Therapeutics | Rare-disease gene therapies | $465M | 4 | December 2015 | $181M | Follow-on Offering | CHOP, Sofinnova, Deerfield | Acquired | Full |
| 37 | TScan Therapeutics | TCR-T cancer cell therapies | $463M | 6 | December 2024 | $30M | Registered direct offering | Lynx1 Capital, BlackRock, RA Capital | IPO | Strong |
| 38 | Poseida Therapeutics | Nonviral cell and gene therapies | $452M | 5 | August 2023 | $25M | Strategic equity investment | Astellas, Novartis, Longitude Capital | Acquired | Strong |
| 39 | Cellectis | Gene-edited allogeneic CAR-T | $448M | 3 | May 2024 | $140M | Strategic equity investment | AstraZeneca | IPO | Partial |
| 40 | Freeline Therapeutics | Systemic AAV gene therapies | $434M | 4 | August 2020 | $159M | IPO | Syncona, Novo Holdings, Eventide Asset Management | Acquired | Strong |
| 41 | Metagenomi | Gene editing medicines | $434M | 4 | February 2024 | $94M | IPO | Leaps by Bayer, Novo Holdings, Catalio Capital | IPO | Full |
| 42 | Vor Biopharma | Engineered stem-cell therapies | $429M | 5 | November 2025 | $100M | Public offering | RA Capital, 5AM Ventures, Fidelity | IPO | Strong |
| 43 | Cabaletta Bio | Autoimmune CAR-T therapies | $426M | 6 | May 2026 | $150M | Public offering | Bain Capital, Adage, Cormorant | IPO | Strong |
| 44 | Lexeo Therapeutics | Cardiovascular gene therapies | $420M | 4 | October 2025 | $135M | Public offering / private placement | Longitude Capital, Omega Funds, Eventide Asset Management | IPO | Full |
| 45 | Immatics | TCR cancer immunotherapies | $415M+ | 4 | July 2023 | $35M | Strategic equity investment | Bristol Myers Squibb, Perceptive Advisors, Wellington Partners | IPO | Partial |
| 46 | Korro Bio | RNA editing medicines | $410M | 4 | March 2026 | $85M | PIPE | Wu Capital, Eventide Asset Management, Venrock | IPO | Full |
| 47 | Voyager Therapeutics | Neurogenetic medicines | $368M | 6 | January 2024 | $100M | Public offering | Third Rock Ventures, Novartis, Wellington Management | IPO | Strong |
| 48 | Umoja Biopharma | In vivo CAR-T therapies | $363M | 3 | January 2025 | $100M | Series C | Double Point, DCVC Bio, ARK Invest | Active | Strong |
| 49 | AvenCell Therapeutics | Switchable CAR-T therapies | $362M | 2 | October 2024 | $112M | Series B | Novo Holdings, F-Prime Capital, Piper Heartland | Active | Full |
| 50 | Senti Biosciences | Programmable cell therapies | $362M | 4 | January 2025 | $48M | PIPE | Celadon Partners, NEA, Leaps by Bayer | IPO | Full |
| 51 | Precision BioSciences | ARCUS gene editing | $361M | 6 | November 2025 | $75M | Public Offering | Aberdeen Investments, Driehaus Capital, Sphera Funds | IPO | Strong |
| 52 | OriCell Therapeutics | Solid-tumor CAR-T therapies | $350M+ | 4 | April 2026 | $110M+ | Pre-IPO | Vivo Capital, Qiming Venture Partners, Beijing Medical Fund | Active | Strong |
| 53 | Capstan Therapeutics | In vivo cell engineering | $340M | 3 | March 2024 | $175M | Series B | RA Capital, Forbion, JJDC | Acquired | Full |
| 54 | Aspen Neuroscience | Autologous neuron replacement | $339M | 4 | November 2025 | $115M | Series C | OrbiMed, ARCH Venture Partners, Frazier Life Sciences | Active | Full |
| 55 | Sonoma Biotherapeutics | Treg cell therapies | $335M | 3 | August 2021 | $265M | Series B | Ally Bridge Group, Deep Track Capital, Fidelity | Active | Full |
| 56 | Obsidian Therapeutics | Engineered TIL therapies | $325M | 3 | April 2024 | $161M | Series C | Wellington Management, Foresite Capital, Novo Holdings | Active | Full |
| 57 | Wugen | Off-the-shelf CAR-T | $323M | 4 | August 2025 | $115M | Series C | Fidelity Management, RiverVest, Lightchain Capital | Active | Partial |
| 58 | Arbor Biotechnologies | Gene editing therapeutics | $305M | 3 | March 2025 | $74M | Series C | ARCH Venture Partners, TCGX, Temasek | Active | Partial |
| 59 | IASO Biotherapeutics | CAR-T cell therapies | $303M | 4 | September 2025 | $60M | Series C extension | GL Ventures, CDH Baifu, Guoxin | Active | Partial |
| 60 | Adaptimmune Therapeutics | TCR-T cancer therapies | $295M | 2 | May 2015 | $191M | IPO | Public investors | IPO | Strong |
| 61 | Beacon Therapeutics | Ophthalmic gene therapies | $289M | 2 | July 2024 | $170M | Series B | Syncona, Forbion, Oxford Science Enterprises | Active | Full |
| 62 | Atara Biotherapeutics | Off-the-shelf T-cell therapies | $282M | 3 | December 2020 | $175M | Public equity offering | Celgene, EcoR1, Kleiner Perkins | IPO | Partial |
| 63 | A2 Biotherapeutics | Logic-gated CAR-T | $271M | 5 | January 2025 | $80M | Series C | The Column Group, Samsara BioCapital, Vida Ventures | Active | Partial |
| 64 | Acepodia | Allogeneic cell cancer therapies | $266M | 4 | June 2023 | $100M | Series D | Digital Mobile Venture, Ridgeback Capital, 8VC | Active | Strong |
| 65 | Quell Therapeutics | Engineered Treg cell therapies | $265M | 4 | January 2023 | $24M | Series B extension | Syncona, Janus Henderson, Monashee | Active | Partial |
| 66 | AIRNA | RNA editing therapeutics | $245M | 3 | April 2025 | $155M | Series B | ARCH Venture Partners, Forbion, Venrock | Active | Full |
| 67 | Adicet Bio | Gamma delta T-cell therapies | $244M | 4 | January 2024 | $98M | Public follow-on | OrbiMed, RA Capital, Novartis Venture Fund | IPO | Partial |
| 68 | AbelZeta Pharma | T-cell cancer therapies | $240M | 8 | September 2021 | $120M | Series A | Sequoia Capital, AstraZeneca-CICC, Yunfeng Capital | Active | Partial |
| 69 | Atsena Therapeutics | Ocular gene therapies | $238M | 4 | April 2025 | $150M | Series C | Bain Capital, Sofinnova, Hatteras | Active | Strong |
| 70 | Asklepios BioPharmaceutical | AAV gene therapy platform | $235M | 1 | April 2019 | $235M | Private equity | TPG Capital, Vida Ventures, founders | Acquired | Partial |
| 71 | Capricor Therapeutics | Cell exosome rare-disease therapies | $230M | 7 | December 2025 | $150M | Public offering | Public investors | IPO | Partial |
| 72 | BlueRock Therapeutics | iPSC-derived cell therapies | $225M | 1 | December 2016 | $225M | Series A | Bayer, Versant Ventures, Leaps by Bayer | Acquired | Full |
| 73 | Affini-T Therapeutics | TCR therapies for tumors | $193M | 2 | October 2024 | $18M | Series A-II | Vida Ventures, Leaps by Bayer, Humboldt Fund | Active | Strong |
| 74 | Celyad Oncology | CAR-T oncology therapies | $192M | 4 | December 2021 | $33M | Private placement | Fortress Investment Group, public investors | IPO | Partial |
| 75 | Gamida Cell | Stem cell transplant therapies | $189M | 4 | October 2018 | $50M | IPO | Shavit Capital, Novartis, Clal Biotechnology | Acquired | Partial |
| 76 | T-knife Therapeutics | TCR-T solid tumor therapies | $188M | 2 | August 2021 | $110M | Series B | Fidelity, LSP, Qatar Investment Authority | Active | Full |
| 77 | Shoreline Biosciences | iPSC NK cell therapies | $183M | 2 | November 2021 | $140M | Series B | Ally Bridge Group, BeiGene, Eventide | Active | Full |
| 78 | GentiBio | Engineered Treg cell therapies | $177M | 2 | August 2021 | $157M | Series A | Matrix Capital, Avidity Partners, JDRF T1D Fund | Active | Full |
| 79 | CRISPR Therapeutics | CRISPR gene editing | $145M | 3 | October 2016 | $56M | IPO | Versant Ventures, SR One, Celgene | IPO | Partial |
| 80 | Interius BioTherapeutics | In vivo CAR therapeutics | $145M | 3 | August 2024 | $67M | Series B | Cormorant, Fairmount, Bain Capital Life Sciences | Acquired | Strong |
| 81 | EXUMA Biotech | Gene-delivered cell therapies | $130M | 4 | December 2021 | $41M | Series B2 | MSD Partners, F1 BioVentures, Sinobioway | Active | Partial |
| 82 | ImmPACT Bio | Logic-gated CAR-T therapies | $129M | 2 | January 2022 | $111M | Series B | venBio, Foresite Capital, Decheng Capital | Active | Strong |
| 83 | Curocell | Korean CAR-T therapies | $107M | 7 | November 2023 | $24M | IPO | Aju IB, IMM Investment, STIC Ventures | IPO | Partial |
| 84 | Bioheng Therapeutics | Allogeneic CAR-T cell therapies | $105M | 4 | June 2022 | $7M | Series B / extension | Zhengxuan Investment, Decheng Capital, GL Ventures | Active | Partial |
| 85 | Juventas Cell Therapy | China CAR-T therapies | $101M | 3 | July 2021 | $63M | Series C | CICC Capital, Oceanpine, Delian Capital | Active | Strong |
| 86 | Triumvira Immunologics | Engineered TAC-T cancer therapies | $100M | 2 | March 2022 | $45M | Series A extension | B Capital Group, Northpond Ventures, Bloom Burton | Active | Strong |
| 87 | Indapta Therapeutics | Allogeneic NK cell therapies | $90M | 2 | December 2024 | $23M | Undisclosed equity | Leaps by Bayer, Myeloma Investment Fund, Pontifax | Active | Partial |
| 88 | Sangamo Therapeutics | Genomic medicine platform | $77M | 2 | March 2024 | $24M | Registered Direct | Institutional investors, placement agents | IPO | Low |
| 89 | Tr1X | Allogeneic Treg cell therapies | $75M | 1 | January 2024 | $75M | Series A | The Column Group, NEVA SGR, Alexandria Ventures | Active | Full |
| 90 | Verismo Therapeutics | KIR-CAR cell therapies | $68M | 4 | April 2026 | $28M | Undisclosed equity | HLB Innovation | Active | Strong |
| 91 | Inceptor Bio | CAR cell therapy platforms | $58M | 2 | February 2025 | $21M | Series A2 | Kineticos Life Sciences | Active | Strong |
| 92 | Immuneel Therapeutics | Affordable CAR-T cancer therapies | $53M | 4 | June 2026 | $11M | Series B | Singularity AMC, Rainmatter, Eight Roads Ventures | Active | Partial |
| 93 | Kelonia Therapeutics | In vivo CAR-T platform | $50M | 1 | April 2022 | $50M | Series A | Alta Partners, Horizons Ventures, Venrock | Active | Full |
| 94 | MiNK Therapeutics | Off-the-shelf iNKT therapies | $46M | 2 | May 2024 | $6M | PIPE | GKCC, public investors | IPO | Strong |
| 95 | Noile-Immune Biotech | PRIME CAR-T cancer therapies | $43M | 3 | June 2023 | $22M | IPO | Dai-ichi Life, Binex, BiGEN | IPO | Partial |
| 96 | Catamaran Bio | Off-the-shelf CAR-NK therapies | $42M | 1 | November 2020 | $42M | Series A | Sofinnova, Lightstone, SV Health | Shutdown | Full |
| 97 | Chimeric Therapeutics | CAR-T and NK therapies | $40M | 6 | December 2025 | $3M | Placement | Bell Potter, Baker Young, L1 Capital | IPO | Partial |
| 98 | AffyImmune Therapeutics | Tuned solid-tumor CAR-T | $38M | 2 | October 2021 | $30M | Series A+ | ORI Capital | Active | Partial |
| 99 | PeproMene Bio | BAFF-R CAR-T therapies | $33M | 2 | June 2018 | $29M | Series B | Not disclosed | Active | Low |
| 100 | Invectys | HLA-G cancer immunotherapies | $31M | 4 | October 2018 | $17M | Series A | Undisclosed family office, Bpifrance | Active | Low |
Key funding trends in the regenerative medicine market
Insights
- The top 10 regenerative medicine startups raised about $13.15B, or roughly 30.6% of the full ranking, showing strong funding concentration around a small group of leaders.
- Cell therapy and CAR-T companies dominate the upper part of the ranking, which suggests investors continue to favor immune-cell engineering platforms with oncology applications.
- Public market financing remains a major funding engine in regenerative medicine, since many leaders reached large totals through IPOs, follow-ons, PIPEs, and registered offerings.
- Active private companies such as ElevateBio, Kriya Therapeutics, ArsenalBio, Aspen Neuroscience, Obsidian Therapeutics, and Beacon Therapeutics show that growth capital is still available for differentiated platforms.
- Gene therapy remains one of the deepest funding categories, with Kriya, Taysha, Spark, Passage Bio, Freeline, Voyager, and other AAV or genetic medicine companies raising large cumulative totals.
- Autoimmune cell therapy is becoming a serious capital theme, with Kyverna, Cabaletta, Tr1X, Sonoma, GentiBio, and Quell showing investor interest beyond cancer treatment.
- Large later-stage private rounds are common in regenerative medicine, especially when platforms combine strong biology, manufacturing depth, and a clear clinical path.
- Strategic pharma participation is visible across the market, with GSK, Gilead, Pfizer, Astellas, Novartis, Bristol Myers Squibb, Bayer, and Novo Nordisk appearing as funders.
A few word about our methodology
As you can see, we built a database that ranks regenerative medicine startups based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.
Whenever possible, we prioritized official company communications, since they are the most reliable source for funding amounts. When those were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times or Forbes (to name a few).
We excluded random blogs, unverified websites, and any sources that could not be validated.
When funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.
Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.
Here is what they mean.
Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.
Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.
Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.
Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.
When the confidence level is too low, we take a conservative approach and exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.
Related blog posts
- How are funding trends changing in the regenerative medicine market?
- Who are the most valuable companies in the regenerative medicine market?
- How active is venture funding in the regenerative medicine market right now?
- An overview of funding deals in the regenerative medicine market
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