Which startups have raised the most funding in the biopharma market?

Last updated: 13 July 2026

A constantly refreshed ranking of the top startups in the biopharma market, based on cumulative funding raised

market research pitch 2026

In our updated market reports, you will find everything you need

The biopharma market is one of the most capital-intensive startup categories, with leading companies often raising hundreds of millions before reaching late clinical stages or public markets.

This ranking is updated every month to keep the list fresh as new IPOs, follow-on offerings, private rounds, and strategic financings are announced.

The table focuses on cumulative equity funding, so it captures how much capital each biopharma startup has raised across its full financing history.

A quick summary table

Metric Value
Most funded startup BeiGene / BeOne Medicines, $5.2B raised
Second most funded startup Vaxcyte, $4.8B raised
Largest funding round Altos Labs, $3.0B launch financing
Median funding $673M
Share of funding captured by the top 10 About 31%
Median time since last round About 2 years and 4 months
Startups that raised funding in the last 12 months 28 startups
Total tracked biopharma startup funding About $91.9B
Largest biopharma platform launch Altos Labs, $3.0B raised in one round
Biopharma startups still private above $600M 8 active private companies

Top startups in the biopharma market ranked by total funding raised

Here is an updated table that ranks the top startups in the biopharma market based on the total amount of funding they have raised to date.

The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected (we excluded startups with very low data confidence, to make sure everything is reliable).

# Startup What They Do Total Raised ($) Total Rounds Last Round Date Last Round Amount ($) Last Round Type Key Investors Current Stage Confidence
1 BeiGene / BeOne Medicines Oncology medicines and immunotherapies $5.2B 9 July 2020 $2.1B Post-IPO equity Amgen, Hillhouse, CITIC Capital IPO Partial
2 Vaxcyte Bacterial disease vaccines $4.8B 15 January 2026 $550M Public offering BofA Securities, Jefferies, Leerink IPO Strong
3 Innovent Biologics Antibodies and oncology biologics $3.5B 13 October 2025 $100M Strategic equity Temasek, Hillhouse, Takeda IPO Strong
4 Altos Labs Cellular rejuvenation therapies $3.0B 1 January 2022 $3.0B Launch financing ARCH Venture Partners, Jeff Bezos, Yuri Milner-linked vehicle Active Strong
5 Moderna mRNA medicines and vaccines $2.3B 7 December 2018 $604M IPO Flagship Ventures, Viking Global, Merck IPO Strong
6 Zai Lab In-licensed innovative medicines for China $2.1B 7 April 2021 $858M Public offering Qiming, Sequoia, OrbiMed IPO Strong
7 National Resilience Biopharma manufacturing infrastructure $2.0B 4 June 2022 $625M Series D ARCH Venture Partners, 8VC, GV Active Partial
8 Roivant Sciences Biopharma company creation platform $1.9B 3 October 2021 $611M SPAC / PIPE SoftBank Vision Fund, NovaQuest, Fidelity IPO Strong
9 BridgeBio Pharma Genetic disease medicines $1.8B 4 July 2026 $1.0B Preferred Equity Sixth Street, KKR, Viking Global IPO Strong
10 Allogene Therapeutics Off-the-shelf CAR-T therapies $1.7B 6 April 2026 $200M Follow-on public offering Goldman Sachs, Jefferies, TD Cowen IPO Strong
11 Kailera Therapeutics Obesity drug pipeline $1.7B 3 April 2026 $719M IPO Public investors, Goldman Sachs, Morgan Stanley IPO Full
12 Parabilis Medicines Undruggable cancer-target peptides $1.7B 8 June 2026 $845M IPO + concurrent placement Regeneron, J.P. Morgan, TD Cowen IPO Strong
13 CRISPR Therapeutics CRISPR gene-editing medicines $1.6B 9 February 2024 $280M Registered direct offering EcoR1 Capital, SR One IPO Strong
14 Apellis Pharmaceuticals Complement-targeted rare disease drugs $1.6B 8 March 2022 $350M Follow-on public offering Public investors, J.P. Morgan, Goldman Sachs Acquired Partial
15 Eikon Therapeutics Live-cell drug discovery $1.5B 5 February 2026 $381M IPO The Column Group, T. Rowe Price, Lux Capital IPO Full
16 Sana Biotechnology Engineered cell medicines $1.5B 4 May 2026 $69M ATM Offering ARCH Venture Partners, Flagship Pioneering, F-Prime Capital IPO Partial
17 Beam Therapeutics Base-editing genetic medicines $1.5B 6 March 2025 $500M Public offering J.P. Morgan, Jefferies, Public investors IPO Strong
18 Intellia Therapeutics In vivo CRISPR therapeutics $1.4B 8 April 2026 $180M Follow-on public offering Jefferies, Goldman Sachs, Citi IPO Strong
19 Arcus Biosciences Cancer immunotherapy combinations $1.4B 7 October 2025 $250M Follow-on public offering Public investors, Morgan Stanley, Goldman Sachs IPO Strong
20 Relay Therapeutics Protein-motion drug discovery $1.4B 6 May 2026 $275M Public Offering Jefferies, TD Cowen, Goldman Sachs IPO Strong
21 XtalPi AI drug discovery platform $1.3B 9 September 2025 $116M Post-IPO Equity Public market investors IPO Partial
22 Crinetics Pharmaceuticals Rare endocrine therapeutics $1.2B 8 January 2026 $350M Public offering Leerink, Morgan Stanley, Piper Sandler Active Strong
23 ElevateBio Cell and gene platform $1.2B 4 May 2023 $401M Series D Matrix Capital, Novo Nordisk, Woodline Active Full
24 Junshi Biosciences Antibody therapeutics for multiple diseases $1.2B 3 July 2020 $717M STAR Market IPO Hillhouse, TR Capital, public investors IPO Strong
25 Generate:Biomedicines AI protein therapeutics $1.1B 4 February 2026 $400M IPO Flagship Pioneering, Amgen, NVentures IPO Strong
26 Legend Biotech CAR-T cell therapies for cancer $1.1B 4 June 2026 $250M Public offering Hudson Bay, JJDC, RA Capital IPO Partial
27 Arcutis Biotherapeutics Dermatology medicines $1.1B 8 February 2024 $150M Public offering Public investors, Morgan Stanley, TD Cowen IPO Strong
28 Xaira Therapeutics AI drug discovery $1.0B 1 April 2024 $1.0B Launch financing ARCH Venture Partners, Foresite Capital, F-Prime Capital Active Strong
29 Lyell Immunopharma T-cell reprogramming therapies $1.0B 3 July 2025 $100M Private placement Institutional investors IPO Strong
30 RemeGen ADCs and autoimmune biologics $1.0B 3 March 2022 $412M STAR Market IPO Lilly Asia Ventures, Lake Bleu, Vivo IPO Strong
31 Editas Medicine CRISPR gene-editing therapies $968M 7 May 2026 $125M Public offering + warrants Cantor, Wells Fargo Securities IPO Strong
32 Kriya Therapeutics Gene therapies for chronic diseases $938M 5 September 2025 $320M Series D Undisclosed, Patient Square Capital, Foresite Capital Active Partial
33 Maze Therapeutics Precision genetic medicines $936M 6 April 2026 $150M Registered offering Farallon Capital Management, T. Rowe Price, public investors IPO Strong
34 Viking Therapeutics Metabolic endocrine therapies $927M 6 March 2024 $633M Public offering Morgan Stanley, Leerink, William Blair IPO Strong
35 BioNTech mRNA immunotherapies and vaccines $925M 4 October 2019 $150M IPO Strüngmann Family, Redmile, Fidelity IPO Full
36 Recursion Pharmaceuticals AI-enabled drug discovery $922M 4 April 2021 $502M IPO Leaps by Bayer, DCVC, Baillie Gifford IPO Partial
37 I-Mab Antibody cancer immunology drugs $907M 4 September 2020 $418M Private Placement Hillhouse Capital, C-Bridge Capital, HBM Healthcare IPO Partial
38 CStone Pharmaceuticals Oncology immunotherapy drug developer $895M 4 September 2020 $200M Strategic Equity Pfizer, GIC, Oriza Seed IPO Full
39 Neumora Therapeutics Precision neuroscience medicines $862M 3 September 2023 $250M IPO Public investors, Amgen, ARCH Venture Partners IPO Full
40 Apogee Therapeutics Inflammation biologics $859M 4 October 2025 $345M Follow-on public offering Public investors, Deep Track Capital, RTW Investments IPO Strong
41 Fate Therapeutics iPSC-derived cell immunotherapies $844M 5 January 2021 $378M Follow-on public offering Public markets IPO Partial
42 Akeso Bispecific antibodies and immunotherapies $825M 6 October 2024 $250M Post-IPO equity Loyal Valley, Sino Biopharm, Shenzhen Capital IPO Partial
43 Everest Medicines Asia-focused licensed medicines $811M 4 October 2020 $451M IPO CBC Group, Janchor Partners, RA Capital IPO Partial
44 Prime Medicine Prime-editing genetic therapies $795M 5 August 2025 $144M Public offering Public investors, Cystic Fibrosis Foundation IPO Strong
45 Alumis Autoimmune precision medicines $779M 4 July 2024 $250M IPO Public investors, Foresite Capital, Samsara BioCapital IPO Full
46 Brii Biosciences Infectious disease biopharma $733M 4 July 2021 $319M IPO ARCH Venture Partners, Invesco, GIC IPO Strong
47 Absci AI biologics drug creation $723M 12 July 2026 $100M Public Offering Eli Lilly, Adage, BVF Partners IPO Partial
48 Verve Therapeutics Cardiovascular gene editing $689M 6 December 2023 $167M Public offering + PIPE Public markets, Eli Lilly IPO Full
49 Cellares Automated cell therapy manufacturing $682M 4 June 2026 $327M Series D BlackRock, Eclipse, Prime Radiant Partners Active Full
50 Century Therapeutics iPSC-derived cell therapies $681M 4 April 2024 $60M PIPE Casdin Capital, Leaps by Bayer, Versant Ventures IPO Full
51 Artiva Biotherapeutics NK cell therapies $665M 4 May 2026 $300M Public offering Venrock, RA Capital, Blackstone IPO Full
52 Arcellx Controllable CAR-T cancer therapies $651M 6 November 2023 $200M Strategic equity Gilead, Novo, NEA Acquired Strong
53 Mirador Therapeutics Immuno-fibrotic precision medicines $650M 2 Q3 2025 $250M Series B ARCH Venture Partners, OrbiMed, Fairmount Active Full
54 Insitro ML drug discovery platform $643M 3 March 2021 $400M Series C CPP Investments, a16z, T. Rowe Price Active Full
55 Insilico Medicine Generative AI drug discovery $643M 4 December 2025 $293M IPO Warburg Pincus, Qiming, Prosperity7 IPO Strong
56 Autolus Therapeutics Engineered T-cell cancer therapies $642M 6 February 2024 $200M Strategic equity Syncona, Blackstone, BioNTech IPO Strong
57 Nimbus Therapeutics Computational small-molecule medicines $637M 9 September 2023 $210M Series F / Private Financing GV, SR One, Atlas Venture Active Partial
58 ArsenalBio Programmable solid-tumor cell therapies $630M 3 September 2024 $325M Series C ARCH Venture Partners, Regeneron Ventures, NVentures Active Full
59 Nkarta Natural killer cell therapies $618M 4 March 2024 $240M Follow-on public offering Adage, Boxer, RA Capital IPO Strong
60 Isomorphic Labs AI drug design $600M 1 March 2025 $600M Series A / external round Thrive Capital, GV, Alphabet Active Partial
61 Denali Therapeutics Neurodegeneration therapeutics $597M 3 December 2017 $250M IPO ARCH, F-Prime, Baillie Gifford IPO Full
62 CARGO Therapeutics CAR-T cancer therapies $591M 3 May 2024 $110M PIPE Third Rock Ventures, RTW Investments, Perceptive Xontogeny Acquired Strong
63 Septerna GPCR-targeted oral medicines $581M 3 October 2024 $331M IPO Public investors, Third Rock Ventures, RA Capital Management IPO Full
64 Tessera Therapeutics Gene writing medicines $580M 3 April 2022 $300M Series C ADIA, Alaska Permanent Fund, SoftBank Vision Fund 2 Active Partial
65 Harbour BioMed Antibody therapeutics platform $534M 6 December 2020 $221M IPO GIC, Hudson Bay Capital, OrbiMed IPO Strong
66 Caribou Biosciences Genome-edited allogeneic cell therapies $520M 4 June 2023 $25M Strategic equity investment Pfizer IPO Partial
67 Ascentage Pharma Apoptosis-targeted cancer therapies $492M 5 January 2025 $126M U.S. IPO YuanMing Capital, Oriza Seed, Teng Yue Partners IPO Partial
68 Kyverna Therapeutics Autoimmune CAR-T therapies $489M 4 February 2024 $319M IPO Northpond Ventures, Vida Ventures, Gilead Sciences IPO Full
69 Iovance Biotherapeutics Tumor-infiltrating lymphocyte therapies $461M 3 February 2024 $211M Follow-on public offering Jefferies, Barclays, Goldman Sachs IPO Low
70 Metagenomi Gene-editing therapeutic platform $444M 5 February 2024 $94M IPO Public investors, Novo Holdings, Catalio IPO Strong
71 Laronde Endless RNA medicines $440M 1 August 2021 $440M Series B Flagship Pioneering, T. Rowe Price, BlackRock Acquired Full
72 BenevolentAI AI-enabled drug discovery $434M 5 April 2022 $152M PIPE / SPAC Financing Temasek, AstraZeneca, Invus Acquired Partial
73 Dizal Pharmaceutical Oncology precision medicines $431M 2 December 2021 $331M IPO Lilly Asia Ventures, SDIC Innovation, HongShan IPO Strong
74 Rapport Therapeutics Precision neuromedicine therapies $424M 3 June 2024 $174M IPO + private placement Third Rock, ARCH, JJDC IPO Full
75 Scholar Rock Growth-factor biology drugs $403M 6 October 2024 $300M Public offering BofA Securities, Jefferies, TD Cowen IPO Partial
76 Valo Health AI drug development platform $400M 3 March 2021 $110M Series B Extension Koch Disruptive Technologies Active Partial
77 GenFleet Therapeutics Oncology immunology therapeutics $399M 8 September 2025 $233M IPO Huagai Capital, Ally Bridge, Baidu Ventures IPO Partial
78 Connect Biopharma T-cell inflammation therapies $386M 5 March 2021 $191M IPO RA Capital, Qiming Venture Partners, Advantech Capital IPO Full
79 Umoja Biopharma In vivo CAR-T therapies $363M 3 January 2025 $100M Series C SoftBank Vision Fund 2, Cormorant, DCVC Bio Active Full
80 ReCode Therapeutics SORT LNP genetic medicines $359M 5 September 2025 $29M Additional equity financing Bioluminescence Ventures, Solasta Ventures, OrbiMed Active Strong
81 Senti Biosciences Gene-circuit cell therapies $346M 5 January 2025 $10M PIPE extension NEA, Leaps by Bayer, Celadon Partners IPO Strong
82 Schrödinger Computational drug discovery software $342M 2 February 2020 $232M IPO Gates Foundation Trust, WuXi, Invus IPO Strong
83 Capstan Therapeutics In vivo RNA cell engineering $340M 3 March 2024 $175M Series B RA Capital, Pfizer Ventures, Novartis Venture Fund Acquired Full
84 Owkin Federated AI precision medicine $304M 3 June 2022 $50M Series B-1 Bristol Myers Squibb, Sanofi, Mubadala Active Strong
85 Orna Therapeutics Circular RNA cell therapies $301M 2 August 2022 $221M Series B Merck, MPM Capital, BioImpact Capital Acquired Strong
86 Latigo Biotherapeutics Non-opioid pain medicines $285M 2 March 2025 $150M Series B Blue Owl, Qatar Investment Authority, 5AM Ventures Active Full
87 Genesis Therapeutics AI small-molecule discovery $280M 4 August 2023 $200M Series B Andreessen Horowitz, Fidelity, BlackRock Active Strong
88 Tarsus Pharmaceuticals Eye disease therapeutics $269M 4 March 2025 $125M Public offering Goldman Sachs, BofA Securities, Barclays IPO Strong
89 Mammoth Biosciences CRISPR therapeutics and diagnostics $263M 5 September 2021 $150M Series D Redmile Group, Foresite Capital, Mayfield Active Strong
90 Sage Therapeutics CNS disorder medicines $235M 3 January 2021 Excluded Ambiguous equity/collaboration financing Third Rock, Biogen, Supernus Acquired Partial
91 Ring Therapeutics Anellovirus gene delivery $230M 3 March 2023 $87M Series C Alexandria Venture Investments, CJ Investment, Kyowa Kirin Active Partial
92 Atomwise AI small-molecule screening $218M 4 March 2024 $44M Later-stage Equity Not fully disclosed Active Partial
93 Asher Biotherapeutics Precision immunotherapy proteins $218M 3 April 2024 $55M Series C Third Rock Ventures, Wellington, RA Capital Active Full
94 CANbridge Pharmaceuticals Rare disease therapeutics $218M 4 December 2021 $77M IPO General Atlantic, WuXi AppTec, 3W Fund IPO Partial
95 Affini-T Therapeutics TCR therapies for tumors $193M 2 October 2024 $18M Undisclosed equity Vida Ventures, Leaps by Bayer, Humboldt Fund Active Partial
96 Cartesian Therapeutics mRNA cell therapies for autoimmune disease $190M 2 July 2024 $130M PIPE HBM Healthcare, Invus, Schooner Capital IPO Partial
97 2seventy bio Cancer cell therapies $170M 1 March 2022 $170M PIPE Institutional investors Acquired Strong
98 Verge Genomics AI neurodegenerative drug discovery $134M 3 December 2021 $98M Series B BlackRock, Eli Lilly, Merck GHI Active Full
99 Alnylam Pharmaceuticals RNAi therapeutics $81M 3 May 2004 $46M IPO Atlas Venture, ARCH, Isis IPO Partial
100 Madrigal Pharmaceuticals MASH liver therapy $73M 2 June 2017 $35M Private placement Existing institutional holders IPO Partial

Key funding trends in the biopharma market

Insights

  • The ten largest biopharma startups captured about $28.3B, or roughly 31% of total tracked funding, which shows how concentrated the market remains
  • Public markets are central to biopharma financing, with most of the top 20 companies using IPOs, follow-on offerings, PIPEs, or other public-market financings
  • Vaxcyte is the clearest repeated-financing story in the ranking, with about $4.8B raised across 15 rounds, far above most similarly funded biopharma companies
  • Altos Labs and Xaira Therapeutics show another model, where massive launch rounds replaced years of traditional venture staging in early biopharma company formation
  • Cell therapy remains one of the most capital-intensive biopharma categories, with major CAR-T, NK cell, and iPSC companies raising about $7.0B combined
  • Gene editing is one of the deepest funding clusters, with Beam, CRISPR Therapeutics, Intellia, Editas, Verve, Prime Medicine, Metagenomi, ArsenalBio, and Mammoth raising around $8.4B
  • AI drug discovery is meaningful, but traditional wet-lab platform companies still dominate the top of the biopharma funding ranking
  • Large 2026 financings changed the top tier, especially BridgeBio Pharma, Kailera Therapeutics, Parabilis Medicines, Vaxcyte, Allogene Therapeutics, and Relay Therapeutics
  • Strategic pharma investors appear across many major rounds, with Amgen, Gilead, Pfizer, BioNTech, Merck, Eli Lilly, Regeneron, and Novo Nordisk backing key companies
  • Obesity and metabolic therapeutics became highly fundable by 2026, with Kailera Therapeutics and Viking Therapeutics raising about $2.6B together

A few word about our methodology

As you can see, we built a database that ranks startups in the biopharma market based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.

Whenever possible, we prioritized official company communications, since company press releases, SEC filings, IPO prospectuses, and investor announcements are often the most reliable sources for biopharma funding amounts. When those were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times, Forbes, Endpoints News, Fierce Biotech, BioPharma Dive, or company investor relations pages.

We excluded random blogs, unverified websites, and any sources that could not be validated.

When funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.

Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.

Here is what they mean.

Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.

Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.

Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.

Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.

When the confidence level is too low, we take a conservative approach and exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.

In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.

If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.

Finally, know that we update the dataset once per month, so come back here if you need fresh information.

Who is the author of this content?

NEW MARKET PITCH TEAM

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How we created this content 🔎📝

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