What are the most valued startups in the mental health market?

Last updated: 13 July 2026

Download our beautiful pitch about the mental health market

market research pitch 2026 statistics mental health market

In our mental health market deck, you will find everything you need to understand the market

The mental health market now includes employer benefits platforms, virtual care providers, clinical software companies, medical devices and neuropsychiatric drug developers.

We update this startup ranking every month to reflect new funding rounds, public market movements, acquisitions and material changes in company performance.

The database currently covers 98 mental health startups with a combined midpoint valuation of approximately $50.4 billion.

And if you want to better understand this new industry, you can download our pitch covering the mental health market.

A quick summary table

Metric Value
Most valuable mental health startup Spring Health, $6.0B–$7.0B
Second most valuable mental health startup MindMed, $6.4B
Median mental health startup valuation Approximately $158M
Share of mental health valuation captured by the top 10 Approximately 62.8%
Top mental health startup valuation vs. median Approximately 41.3 times
Median valuation-to-capital-raised ratio Approximately 3.0 times
Mental health startups valued at $1B+ 11
Market map chart showing top companies and startups in the mental health market

This market map, featured in our mental health market deck, highlights top companies and startups in the mental health market

Top startups in the mental health market ranked by valuation

Here is an updated table that ranks the top startups in the mental health market based on their latest reported or estimated valuations.

If you want more detaild about their fundraising activity, you can check our list of the startups who have raised the most funding in the mental health market.

# Startup Name What They Do Current Valuation ($) Valuation Confidence Level Valuation Type Evidence Status Total Funding ($) Funding Confidence Level
1 Spring Health Employer mental health benefits platform $6.0B–$7.0B Strong Confidence Acquisition Value Estimated $450M Strong Confidence
2 MindMed Psychedelic neuropsychiatric drug development $6.4B Full Confidence Public Market Cap Observed $700M Strong Confidence
3 Lyra Health Employer mental health platform $5.6B–$5.9B Strong Confidence Revenue or ARR Multiple Estimate Estimated $900M Strong Confidence
4 Grow Therapy Insurance-based therapy marketplace $2.9B–$3.1B Strong Confidence Announced Private Round Valuation Observed $100M Partial Confidence
5 Headway Therapist insurance marketplace $2.2B–$2.5B Strong Confidence Announced Private Round Valuation Observed $225M Strong Confidence
6 Compass Pathways Psychedelic depression therapy developer $1.8B Full Confidence Public Market Cap Observed $300M Full Confidence
7 Talkiatry In-network virtual psychiatry provider $1.2B–$2.0B Partial Confidence Implied Valuation from Raise Implied $150M Partial Confidence
8 Charlie Health Virtual intensive mental healthcare $1.2B–$1.8B Partial Confidence Revenue or ARR Multiple Estimate Estimated $404M Partial Confidence
9 Alma Therapist practice enablement platform $1.2B–$1.8B Partial Confidence Acquisition Value Estimated $221M Strong Confidence
10 atai Life Sciences Psychedelic mental health therapeutics $1.2B Full Confidence Public Market Cap Observed $778M Strong Confidence
11 Cognito Therapeutics Alzheimer’s neuromodulation device therapy $700M–$1.3B Partial Confidence Implied Valuation from Raise Implied $233M Strong Confidence
12 Talkspace Online therapy and psychiatry $872M Full Confidence Public Market Cap Observed $300M Full Confidence
13 Draig Therapeutics Neuropsychiatric drug developer $700M–$950M Strong Confidence Implied Valuation from Raise Implied $140M Strong Confidence
14 Cerebral Online psychiatry platform $600M–$1.0B Low Confidence Revenue or ARR Multiple Estimate Estimated $300M Partial Confidence
15 Gilgamesh Pharmaceuticals Neuropsychiatric small-molecule drug developer $400M–$1.2B Partial Confidence Acquisition Value Observed $129M Partial Confidence
16 Author Health Senior behavioral health care $575M–$900M Partial Confidence Implied Valuation from Raise Implied $115M Full Confidence
17 Cortica Whole-child autism care provider $530M–$800M Partial Confidence Implied Valuation from Raise Implied $255M Strong Confidence
18 SonderMind Therapy matching care platform $450M–$850M Low Confidence Comparables-Based Estimate Estimated $183M Full Confidence
19 Bright Minds Biosciences Serotonergic neuroscience drug developer $629M Full Confidence Public Market Cap Observed $232M Strong Confidence
20 Eleos Health Behavioral health AI documentation $450M–$650M Strong Confidence Implied Valuation from Raise Implied $128M Full Confidence
21 Two Chairs In-network therapy provider $380M–$550M Partial Confidence Implied Valuation from Raise Implied $83M Strong Confidence
22 Click Therapeutics Prescription digital therapeutics developer $350M–$500M Strong Confidence Implied Valuation from Raise Implied $150M Strong Confidence
23 Brightline Pediatric virtual behavioral care $300M–$550M Low Confidence Comparables-Based Estimate Estimated $205M Strong Confidence
24 Cybin Psychedelic neuropsychiatry drug developer $420M Full Confidence Public Market Cap Observed $486M Strong Confidence
25 Beckley Psytech Short-duration psychedelic medicines $390M Strong Confidence Acquisition Value Observed $142M Strong Confidence
26 AnswersNow Virtual autism therapy provider $270M–$500M Strong Confidence Implied Valuation from Raise Implied $51M Partial Confidence
27 Delix Therapeutics Neuroplasticity-focused psychiatric medicines $250M–$450M Partial Confidence Comparables-Based Estimate Estimated $70M Partial Confidence
28 Forta AI-enabled autism therapy $250M–$400M Partial Confidence Implied Valuation from Raise Implied $55M Full Confidence
29 Brightside Health Virtual mood disorder care $240M–$410M Partial Confidence Implied Valuation from Raise Implied $109M Strong Confidence
30 Pelago Virtual substance-use treatment $250M–$400M Partial Confidence Comparables-Based Estimate Estimated $151M Partial Confidence
31 Holmusk Behavioral health data analytics $230M–$380M Partial Confidence Implied Valuation from Raise Implied $109M Partial Confidence
32 Octave In-network therapy network $220M–$360M Partial Confidence Implied Valuation from Raise Implied $88M Strong Confidence
33 InStride Health Youth anxiety and OCD treatment $240M–$330M Strong Confidence Implied Valuation from Raise Implied $86M Full Confidence
34 Cartwheel Care School-based youth mental healthcare $230M–$320M Strong Confidence Implied Valuation from Raise Implied $59M Partial Confidence
35 NOCD OCD specialty telehealth $240M–$300M Partial Confidence Comparables-Based Estimate Estimated $84M Full Confidence
36 Ophelia Virtual opioid-use disorder treatment $240M–$300M Strong Confidence Comparables-Based Estimate Estimated $68M Full Confidence
37 Big Health Prescription digital therapeutics $160M–$300M Partial Confidence Implied Valuation from Raise Implied $153M Partial Confidence
38 Amae Health Severe mental illness clinics $180M–$260M Strong Confidence Implied Valuation from Raise Implied $50M Partial Confidence
39 Concert Health Collaborative behavioral care $160M–$280M Partial Confidence Implied Valuation from Raise Implied $58M Partial Confidence
40 Affect Therapeutics App-based addiction recovery care $170M–$260M Strong Confidence Implied Valuation from Raise Implied $22M Strong Confidence
41 Iris Telehealth Telepsychiatry for health systems $150M–$250M Partial Confidence Implied Valuation from Raise Implied $40M Strong Confidence
42 Boulder Care Virtual addiction treatment $150M–$210M Strong Confidence Implied Valuation from Raise Implied $85M Strong Confidence
43 Meru Health Digital mental health programs $150M–$200M Strong Confidence Comparables-Based Estimate Estimated $42M Partial Confidence
44 firsthand Serious mental illness support $140M–$210M Partial Confidence Implied Valuation from Raise Implied $43M Partial Confidence
45 NeuroFlow Behavioral health integration $130M–$220M Partial Confidence Implied Valuation from Raise Implied $55M Strong Confidence
46 Array Behavioral Care Virtual psychiatry and therapy $130M–$200M Partial Confidence Implied Valuation from Raise Implied $49M Strong Confidence
47 PursueCare Virtual addiction treatment services $120M–$210M Partial Confidence Implied Valuation from Raise Implied $31M Strong Confidence
48 Bicycle Health Virtual opioid-use disorder care $130M–$190M Strong Confidence Implied Valuation from Raise Implied $104M Strong Confidence
49 Freespira At-home PTSD and panic treatment $130M–$190M Partial Confidence Implied Valuation from Raise Implied $49M Partial Confidence
50 Eleanor Health Integrated addiction healthcare $120M–$190M Partial Confidence Implied Valuation from Raise Implied $82M Strong Confidence
51 Bend Health Pediatric collaborative mental healthcare $120M–$190M Partial Confidence Acquisition Value Estimated $32M Partial Confidence
52 Mindbloom At-home ketamine therapy $100M–$180M Low Confidence Comparables-Based Estimate Estimated $45M Low Confidence
53 Brave Health Medicaid behavioral healthcare $105M–$145M Strong Confidence Comparables-Based Estimate Estimated $61M Partial Confidence
54 Uwill Campus mental health platform $100M–$150M Partial Confidence Revenue or ARR Multiple Estimate Estimated $39M Full Confidence
55 Tava Health Employer-sponsored online mental healthcare $100M–$150M Partial Confidence Implied Valuation from Raise Implied $33M Full Confidence
56 Valera Health High-acuity virtual mental healthcare $90M–$150M Low Confidence Implied Valuation from Raise Implied $74M Partial Confidence
57 Ria Health Telehealth alcohol-use treatment $85M–$145M Partial Confidence Implied Valuation from Raise Implied $31M Partial Confidence
58 Opya Early autism intervention services $90M–$140M Low Confidence Comparables-Based Estimate Estimated $22M Partial Confidence
59 Workit Health Virtual addiction treatment $90M–$125M Strong Confidence Revenue or ARR Multiple Estimate Estimated $136M Partial Confidence
60 Neuronetics TMS depression medical devices $107M Full Confidence Public Market Cap Observed $120M Full Confidence
61 Blackbird Health Youth precision mental healthcare $85M–$120M Partial Confidence Implied Valuation from Raise Implied $23M Partial Confidence
62 Lykos Therapeutics MDMA-assisted PTSD drug developer $70M–$130M Partial Confidence Implied Valuation from Raise Estimated $150M Strong Confidence
63 Little Otter Family mental healthcare platform $80M–$105M Strong Confidence Comparables-Based Estimate Estimated $36M Full Confidence
64 Backpack Healthcare Medicaid pediatric behavioral healthcare $75M–$110M Partial Confidence Implied Valuation from Raise Implied $18M Partial Confidence
65 Magstim TMS and EEG systems manufacturer $70M–$110M Low Confidence Comparables-Based Estimate Estimated $32M Low Confidence
66 aptihealth Higher-acuity virtual care $60M–$110M Low Confidence Implied Valuation from Raise Implied $50M Partial Confidence
67 Healios Online youth mental healthcare $65M–$100M Partial Confidence Comparables-Based Estimate Estimated $54M Strong Confidence
68 Wayspring Value-based addiction care $65M–$95M Partial Confidence Revenue or ARR Multiple Estimate Estimated $117M Partial Confidence
69 SpectrumAi Autism outcomes analytics software $60M–$100M Low Confidence Acquisition Value Estimated $29M Full Confidence
70 Osmind Neuropsychiatry EHR platform $45M–$90M Low Confidence Revenue or ARR Multiple Estimate Estimated $57M Full Confidence
71 Quartet Health Behavioral care coordination platform $40M–$90M Low Confidence Acquisition Value Estimated $160M Strong Confidence
72 NUE Life Health Ketamine mental wellness platform $45M–$75M Low Confidence Comparables-Based Estimate Estimated $26M Partial Confidence
73 BehaVR VR behavioral health therapeutics $45M–$75M Partial Confidence Implied Valuation from Raise Implied $21M Partial Confidence
74 Birches Health Behavioral addiction telehealth care $50M–$65M Strong Confidence Implied Valuation from Raise Implied $20M Partial Confidence
75 HelloSelf Online therapy and psychiatry $45M–$70M Partial Confidence Revenue or ARR Multiple Estimate Estimated $32M Partial Confidence
76 Mantra Health College mental health services $45M–$65M Low Confidence Comparables-Based Estimate Estimated $32M Full Confidence
77 Flow Neuroscience Depression brain-stimulation headset $40M–$65M Partial Confidence Revenue or ARR Multiple Estimate Estimated $12M Full Confidence
78 Journey Clinical Psychedelic therapy infrastructure $36M–$60M Partial Confidence Implied Valuation from Raise Implied $12M Partial Confidence
79 Marigold Health Peer-based behavioral healthcare $35M–$55M Partial Confidence Comparables-Based Estimate Estimated $17M Partial Confidence
80 Psylo Non-hallucinogenic neuroplastogen developer $35M–$55M Partial Confidence Implied Valuation from Raise Implied $14M Strong Confidence
81 Fort Health Pediatric integrated mental healthcare $35M–$55M Partial Confidence Implied Valuation from Raise Implied $16M Strong Confidence
82 GrayMatters Health PTSD neurofeedback treatment platform $35M–$55M Low Confidence Implied Valuation from Raise Implied $10M Strong Confidence
83 Monument Online alcohol-use treatment $35M–$52M Partial Confidence Comparables-Based Estimate Estimated $24M Partial Confidence
84 Clerkenwell Health Psychedelic clinical-trial services $25M–$45M Low Confidence Revenue or ARR Multiple Estimate Estimated $3M Strong Confidence
85 Happify Health / Twill Digital therapeutic care platform $34M Strong Confidence Acquisition Value Observed $122M Partial Confidence
86 Akili Interactive Prescription digital therapeutic games $34M Full Confidence Acquisition Value Observed $230M Partial Confidence
87 Manatee Digital family mental healthcare $25M–$40M Low Confidence Comparables-Based Estimate Estimated $9M Partial Confidence
88 Psyomics AI mental health assessment software $25M–$38M Partial Confidence Implied Valuation from Raise Implied $17M Partial Confidence
89 ieso Digital CBT therapy $25M–$35M Partial Confidence Acquisition Value Estimated $77M Partial Confidence
90 OxfordVR Automated VR psychological therapy $20M–$35M Low Confidence Acquisition Value Estimated $19M Strong Confidence
91 Small Pharma Short-duration psychedelic therapeutics $24M Strong Confidence Acquisition Value Observed $49M Partial Confidence
92 Woebot Health AI mental health chatbot $5M–$25M Low Confidence Proxy-Based Estimate Estimated $124M Partial Confidence
93 Innerwell Psychedelic-assisted therapy platform $10M–$20M Low Confidence Implied Valuation from Raise Implied $3M Full Confidence
94 Sonara Health Remote methadone adherence monitoring $8M–$16M Low Confidence Proxy-Based Estimate Estimated $6M Partial Confidence
95 Numinus Psychedelic-assisted therapy clinics $5M–$15M Low Confidence Proxy-Based Estimate Estimated $50M Partial Confidence
96 DynamiCare Health Addiction recovery rewards platform $7M–$12M Low Confidence Proxy-Based Estimate Estimated $6M Full Confidence
97 Awakn Life Sciences Addiction-focused psychedelic therapeutics $3M–$6M Partial Confidence Acquisition Value Implied $14M Partial Confidence
98 Braxia Scientific Ketamine clinics and research $0M–$2M Low Confidence Proxy-Based Estimate Estimated $2M Low Confidence
Chart comparing the 2026 size of the mental health market with other markets of similar size

This chart, featured in our mental health market deck, compares the 2026 size of the mental health market with other markets of similar size

Key valuation trends in the mental health market

Insights

  • Spring Health, MindMed and Lyra Health represent approximately $18.7 billion in combined midpoint valuation, equal to more than one-third of the value tracked across the mental health startup ranking.
  • The top 10 mental health startups capture about 62.8% of the dataset’s total valuation, showing that sector value remains concentrated in a small group of scaled platforms and drug developers.
  • Spring Health and Lyra Health carry a combined midpoint valuation of approximately $12.3 billion, which shows how strongly investors value employer-funded mental health distribution and recurring enterprise contracts.
  • Headway’s midpoint valuation is more than ten times its disclosed funding, while Grow Therapy’s ratio reaches approximately 30 times, highlighting the capital efficiency of insurance-connected therapy marketplaces.
  • MindMed alone is valued above Compass Pathways, atai Life Sciences, Bright Minds Biosciences and Cybin combined, showing how concentrated public psychedelic valuations have become.
  • Eleos Health’s estimated $550 million midpoint valuation is more than four times its funding, suggesting that behavioral health AI creates greater value when embedded in clinical workflows rather than sold as a general wellness chatbot.
  • Ophelia, Boulder Care and Bicycle Health support approximately $610 million in combined midpoint valuation, showing that specialized opioid-treatment platforms can reach meaningful scale without offering every category of mental healthcare.
  • Affect Therapeutics has a midpoint valuation near $215 million against only $22 million raised, producing one of the strongest valuation-to-funding ratios in the addiction-care segment.
  • Several acquired digital therapeutics businesses produced weak outcomes. Akili Interactive and Happify Health were acquired for a combined $68 million after raising approximately $352 million.
  • The median startup in this ranking is valued at approximately $158 million, while the leading company’s midpoint valuation is more than 41 times higher, reflecting the mental health market’s unusually wide range of outcomes.
Chart showing why Talkspace is winning in the mental health market

This chart, featured in our mental health market deck, shows why Talkspace is winning in mental health

A few word about our methodology

As you can see, we built a database that ranks startups in the mental health market based on their current valuation.

Estimating mental health startup valuations is not always straightforward. Many companies do not publicly disclose their valuation, and the available information can vary widely depending on the company, business model and development stage.

To build this ranking, we applied a structured valuation methodology and cross-checked information across multiple reliable sources.

Whenever possible, we relied on direct disclosures. These include announced valuations from completed funding rounds, public filings for listed mental health companies or official acquisition prices.

When a mental health company is publicly listed, we use its current market capitalization as the reference valuation.

If a company was acquired and no independent valuation can reasonably be estimated today, we use the acquisition price as the main reference point.

When a startup recently raised capital but the valuation was not disclosed, we estimate the implied valuation using typical dilution levels for that stage of fundraising.

In some cases, we also estimate valuations using operating metrics such as revenue, ARR, covered lives, patient volume or customer traction. We combine these metrics with valuation multiples from comparable mental health companies.

For clinical-stage biotechnology companies, we may also consider the maturity of the drug pipeline, trial results, addressable patient populations, licensing transactions and valuations of comparable neuropsychiatric developers.

For care-delivery platforms, we examine reimbursement coverage, payer relationships, clinician capacity, patient retention and the ability to serve clearly defined populations.

When direct financial data is not available, we may rely on carefully selected comparable startups and other signals such as hiring growth, investor quality, payer contracts, regulatory progress or product traction.

All estimates follow a strict evidence hierarchy. Recent funding rounds with announced valuations carry the most weight, followed by strong operating metrics and comparable company analysis.

We also carefully evaluate the age of every data point. Recent information carries more weight, while older data is treated cautiously and adjusted conservatively when necessary.

Whenever information is uncertain or incomplete, we clearly distinguish between confirmed facts and reasonable inferences.

Because valuation data is not always fully public, each mental health startup in the ranking is assigned a confidence level based on the reliability, recency and consistency of the available evidence.

Full confidence means the valuation is supported by strong and recent evidence. Strong confidence means the estimate is well supported but includes minor inference. Partial confidence means the estimate relies more heavily on indirect signals. Low confidence means available information is limited or inconsistent.

When confidence is lower, we take a more conservative approach by widening the valuation range. This helps reflect the uncertainty and increases the probability that the true valuation falls within the estimated range.

This reflects how we conduct all our research, including the work behind our report covering the mental health market.

In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.

If you want the full detail on a specific valuation estimate, feel free to contact us and we will gladly explain.

Finally, know that we update the dataset once per month, so come back here if you need fresh information.

Chart showing the projected CAGR of the mental health market

This chart, featured in our mental health market deck, illustrates yearly funding for mental health startups

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