What are the most valued startups in the mental health market?
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In our mental health market deck, you will find everything you need to understand the market
The mental health market now includes employer benefits platforms, virtual care providers, clinical software companies, medical devices and neuropsychiatric drug developers.
We update this startup ranking every month to reflect new funding rounds, public market movements, acquisitions and material changes in company performance.
The database currently covers 98 mental health startups with a combined midpoint valuation of approximately $50.4 billion.
And if you want to better understand this new industry, you can download our pitch covering the mental health market.
A quick summary table
| Metric | Value |
|---|---|
| Most valuable mental health startup | Spring Health, $6.0B–$7.0B |
| Second most valuable mental health startup | MindMed, $6.4B |
| Median mental health startup valuation | Approximately $158M |
| Share of mental health valuation captured by the top 10 | Approximately 62.8% |
| Top mental health startup valuation vs. median | Approximately 41.3 times |
| Median valuation-to-capital-raised ratio | Approximately 3.0 times |
| Mental health startups valued at $1B+ | 11 |

This market map, featured in our mental health market deck, highlights top companies and startups in the mental health market
Top startups in the mental health market ranked by valuation
Here is an updated table that ranks the top startups in the mental health market based on their latest reported or estimated valuations.
If you want more detaild about their fundraising activity, you can check our list of the startups who have raised the most funding in the mental health market.
| # | Startup Name | What They Do | Current Valuation ($) | Valuation Confidence Level | Valuation Type | Evidence Status | Total Funding ($) | Funding Confidence Level |
|---|---|---|---|---|---|---|---|---|
| 1 | Spring Health | Employer mental health benefits platform | $6.0B–$7.0B | Strong Confidence | Acquisition Value | Estimated | $450M | Strong Confidence |
| 2 | MindMed | Psychedelic neuropsychiatric drug development | $6.4B | Full Confidence | Public Market Cap | Observed | $700M | Strong Confidence |
| 3 | Lyra Health | Employer mental health platform | $5.6B–$5.9B | Strong Confidence | Revenue or ARR Multiple Estimate | Estimated | $900M | Strong Confidence |
| 4 | Grow Therapy | Insurance-based therapy marketplace | $2.9B–$3.1B | Strong Confidence | Announced Private Round Valuation | Observed | $100M | Partial Confidence |
| 5 | Headway | Therapist insurance marketplace | $2.2B–$2.5B | Strong Confidence | Announced Private Round Valuation | Observed | $225M | Strong Confidence |
| 6 | Compass Pathways | Psychedelic depression therapy developer | $1.8B | Full Confidence | Public Market Cap | Observed | $300M | Full Confidence |
| 7 | Talkiatry | In-network virtual psychiatry provider | $1.2B–$2.0B | Partial Confidence | Implied Valuation from Raise | Implied | $150M | Partial Confidence |
| 8 | Charlie Health | Virtual intensive mental healthcare | $1.2B–$1.8B | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $404M | Partial Confidence |
| 9 | Alma | Therapist practice enablement platform | $1.2B–$1.8B | Partial Confidence | Acquisition Value | Estimated | $221M | Strong Confidence |
| 10 | atai Life Sciences | Psychedelic mental health therapeutics | $1.2B | Full Confidence | Public Market Cap | Observed | $778M | Strong Confidence |
| 11 | Cognito Therapeutics | Alzheimer’s neuromodulation device therapy | $700M–$1.3B | Partial Confidence | Implied Valuation from Raise | Implied | $233M | Strong Confidence |
| 12 | Talkspace | Online therapy and psychiatry | $872M | Full Confidence | Public Market Cap | Observed | $300M | Full Confidence |
| 13 | Draig Therapeutics | Neuropsychiatric drug developer | $700M–$950M | Strong Confidence | Implied Valuation from Raise | Implied | $140M | Strong Confidence |
| 14 | Cerebral | Online psychiatry platform | $600M–$1.0B | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $300M | Partial Confidence |
| 15 | Gilgamesh Pharmaceuticals | Neuropsychiatric small-molecule drug developer | $400M–$1.2B | Partial Confidence | Acquisition Value | Observed | $129M | Partial Confidence |
| 16 | Author Health | Senior behavioral health care | $575M–$900M | Partial Confidence | Implied Valuation from Raise | Implied | $115M | Full Confidence |
| 17 | Cortica | Whole-child autism care provider | $530M–$800M | Partial Confidence | Implied Valuation from Raise | Implied | $255M | Strong Confidence |
| 18 | SonderMind | Therapy matching care platform | $450M–$850M | Low Confidence | Comparables-Based Estimate | Estimated | $183M | Full Confidence |
| 19 | Bright Minds Biosciences | Serotonergic neuroscience drug developer | $629M | Full Confidence | Public Market Cap | Observed | $232M | Strong Confidence |
| 20 | Eleos Health | Behavioral health AI documentation | $450M–$650M | Strong Confidence | Implied Valuation from Raise | Implied | $128M | Full Confidence |
| 21 | Two Chairs | In-network therapy provider | $380M–$550M | Partial Confidence | Implied Valuation from Raise | Implied | $83M | Strong Confidence |
| 22 | Click Therapeutics | Prescription digital therapeutics developer | $350M–$500M | Strong Confidence | Implied Valuation from Raise | Implied | $150M | Strong Confidence |
| 23 | Brightline | Pediatric virtual behavioral care | $300M–$550M | Low Confidence | Comparables-Based Estimate | Estimated | $205M | Strong Confidence |
| 24 | Cybin | Psychedelic neuropsychiatry drug developer | $420M | Full Confidence | Public Market Cap | Observed | $486M | Strong Confidence |
| 25 | Beckley Psytech | Short-duration psychedelic medicines | $390M | Strong Confidence | Acquisition Value | Observed | $142M | Strong Confidence |
| 26 | AnswersNow | Virtual autism therapy provider | $270M–$500M | Strong Confidence | Implied Valuation from Raise | Implied | $51M | Partial Confidence |
| 27 | Delix Therapeutics | Neuroplasticity-focused psychiatric medicines | $250M–$450M | Partial Confidence | Comparables-Based Estimate | Estimated | $70M | Partial Confidence |
| 28 | Forta | AI-enabled autism therapy | $250M–$400M | Partial Confidence | Implied Valuation from Raise | Implied | $55M | Full Confidence |
| 29 | Brightside Health | Virtual mood disorder care | $240M–$410M | Partial Confidence | Implied Valuation from Raise | Implied | $109M | Strong Confidence |
| 30 | Pelago | Virtual substance-use treatment | $250M–$400M | Partial Confidence | Comparables-Based Estimate | Estimated | $151M | Partial Confidence |
| 31 | Holmusk | Behavioral health data analytics | $230M–$380M | Partial Confidence | Implied Valuation from Raise | Implied | $109M | Partial Confidence |
| 32 | Octave | In-network therapy network | $220M–$360M | Partial Confidence | Implied Valuation from Raise | Implied | $88M | Strong Confidence |
| 33 | InStride Health | Youth anxiety and OCD treatment | $240M–$330M | Strong Confidence | Implied Valuation from Raise | Implied | $86M | Full Confidence |
| 34 | Cartwheel Care | School-based youth mental healthcare | $230M–$320M | Strong Confidence | Implied Valuation from Raise | Implied | $59M | Partial Confidence |
| 35 | NOCD | OCD specialty telehealth | $240M–$300M | Partial Confidence | Comparables-Based Estimate | Estimated | $84M | Full Confidence |
| 36 | Ophelia | Virtual opioid-use disorder treatment | $240M–$300M | Strong Confidence | Comparables-Based Estimate | Estimated | $68M | Full Confidence |
| 37 | Big Health | Prescription digital therapeutics | $160M–$300M | Partial Confidence | Implied Valuation from Raise | Implied | $153M | Partial Confidence |
| 38 | Amae Health | Severe mental illness clinics | $180M–$260M | Strong Confidence | Implied Valuation from Raise | Implied | $50M | Partial Confidence |
| 39 | Concert Health | Collaborative behavioral care | $160M–$280M | Partial Confidence | Implied Valuation from Raise | Implied | $58M | Partial Confidence |
| 40 | Affect Therapeutics | App-based addiction recovery care | $170M–$260M | Strong Confidence | Implied Valuation from Raise | Implied | $22M | Strong Confidence |
| 41 | Iris Telehealth | Telepsychiatry for health systems | $150M–$250M | Partial Confidence | Implied Valuation from Raise | Implied | $40M | Strong Confidence |
| 42 | Boulder Care | Virtual addiction treatment | $150M–$210M | Strong Confidence | Implied Valuation from Raise | Implied | $85M | Strong Confidence |
| 43 | Meru Health | Digital mental health programs | $150M–$200M | Strong Confidence | Comparables-Based Estimate | Estimated | $42M | Partial Confidence |
| 44 | firsthand | Serious mental illness support | $140M–$210M | Partial Confidence | Implied Valuation from Raise | Implied | $43M | Partial Confidence |
| 45 | NeuroFlow | Behavioral health integration | $130M–$220M | Partial Confidence | Implied Valuation from Raise | Implied | $55M | Strong Confidence |
| 46 | Array Behavioral Care | Virtual psychiatry and therapy | $130M–$200M | Partial Confidence | Implied Valuation from Raise | Implied | $49M | Strong Confidence |
| 47 | PursueCare | Virtual addiction treatment services | $120M–$210M | Partial Confidence | Implied Valuation from Raise | Implied | $31M | Strong Confidence |
| 48 | Bicycle Health | Virtual opioid-use disorder care | $130M–$190M | Strong Confidence | Implied Valuation from Raise | Implied | $104M | Strong Confidence |
| 49 | Freespira | At-home PTSD and panic treatment | $130M–$190M | Partial Confidence | Implied Valuation from Raise | Implied | $49M | Partial Confidence |
| 50 | Eleanor Health | Integrated addiction healthcare | $120M–$190M | Partial Confidence | Implied Valuation from Raise | Implied | $82M | Strong Confidence |
| 51 | Bend Health | Pediatric collaborative mental healthcare | $120M–$190M | Partial Confidence | Acquisition Value | Estimated | $32M | Partial Confidence |
| 52 | Mindbloom | At-home ketamine therapy | $100M–$180M | Low Confidence | Comparables-Based Estimate | Estimated | $45M | Low Confidence |
| 53 | Brave Health | Medicaid behavioral healthcare | $105M–$145M | Strong Confidence | Comparables-Based Estimate | Estimated | $61M | Partial Confidence |
| 54 | Uwill | Campus mental health platform | $100M–$150M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $39M | Full Confidence |
| 55 | Tava Health | Employer-sponsored online mental healthcare | $100M–$150M | Partial Confidence | Implied Valuation from Raise | Implied | $33M | Full Confidence |
| 56 | Valera Health | High-acuity virtual mental healthcare | $90M–$150M | Low Confidence | Implied Valuation from Raise | Implied | $74M | Partial Confidence |
| 57 | Ria Health | Telehealth alcohol-use treatment | $85M–$145M | Partial Confidence | Implied Valuation from Raise | Implied | $31M | Partial Confidence |
| 58 | Opya | Early autism intervention services | $90M–$140M | Low Confidence | Comparables-Based Estimate | Estimated | $22M | Partial Confidence |
| 59 | Workit Health | Virtual addiction treatment | $90M–$125M | Strong Confidence | Revenue or ARR Multiple Estimate | Estimated | $136M | Partial Confidence |
| 60 | Neuronetics | TMS depression medical devices | $107M | Full Confidence | Public Market Cap | Observed | $120M | Full Confidence |
| 61 | Blackbird Health | Youth precision mental healthcare | $85M–$120M | Partial Confidence | Implied Valuation from Raise | Implied | $23M | Partial Confidence |
| 62 | Lykos Therapeutics | MDMA-assisted PTSD drug developer | $70M–$130M | Partial Confidence | Implied Valuation from Raise | Estimated | $150M | Strong Confidence |
| 63 | Little Otter | Family mental healthcare platform | $80M–$105M | Strong Confidence | Comparables-Based Estimate | Estimated | $36M | Full Confidence |
| 64 | Backpack Healthcare | Medicaid pediatric behavioral healthcare | $75M–$110M | Partial Confidence | Implied Valuation from Raise | Implied | $18M | Partial Confidence |
| 65 | Magstim | TMS and EEG systems manufacturer | $70M–$110M | Low Confidence | Comparables-Based Estimate | Estimated | $32M | Low Confidence |
| 66 | aptihealth | Higher-acuity virtual care | $60M–$110M | Low Confidence | Implied Valuation from Raise | Implied | $50M | Partial Confidence |
| 67 | Healios | Online youth mental healthcare | $65M–$100M | Partial Confidence | Comparables-Based Estimate | Estimated | $54M | Strong Confidence |
| 68 | Wayspring | Value-based addiction care | $65M–$95M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $117M | Partial Confidence |
| 69 | SpectrumAi | Autism outcomes analytics software | $60M–$100M | Low Confidence | Acquisition Value | Estimated | $29M | Full Confidence |
| 70 | Osmind | Neuropsychiatry EHR platform | $45M–$90M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $57M | Full Confidence |
| 71 | Quartet Health | Behavioral care coordination platform | $40M–$90M | Low Confidence | Acquisition Value | Estimated | $160M | Strong Confidence |
| 72 | NUE Life Health | Ketamine mental wellness platform | $45M–$75M | Low Confidence | Comparables-Based Estimate | Estimated | $26M | Partial Confidence |
| 73 | BehaVR | VR behavioral health therapeutics | $45M–$75M | Partial Confidence | Implied Valuation from Raise | Implied | $21M | Partial Confidence |
| 74 | Birches Health | Behavioral addiction telehealth care | $50M–$65M | Strong Confidence | Implied Valuation from Raise | Implied | $20M | Partial Confidence |
| 75 | HelloSelf | Online therapy and psychiatry | $45M–$70M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $32M | Partial Confidence |
| 76 | Mantra Health | College mental health services | $45M–$65M | Low Confidence | Comparables-Based Estimate | Estimated | $32M | Full Confidence |
| 77 | Flow Neuroscience | Depression brain-stimulation headset | $40M–$65M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $12M | Full Confidence |
| 78 | Journey Clinical | Psychedelic therapy infrastructure | $36M–$60M | Partial Confidence | Implied Valuation from Raise | Implied | $12M | Partial Confidence |
| 79 | Marigold Health | Peer-based behavioral healthcare | $35M–$55M | Partial Confidence | Comparables-Based Estimate | Estimated | $17M | Partial Confidence |
| 80 | Psylo | Non-hallucinogenic neuroplastogen developer | $35M–$55M | Partial Confidence | Implied Valuation from Raise | Implied | $14M | Strong Confidence |
| 81 | Fort Health | Pediatric integrated mental healthcare | $35M–$55M | Partial Confidence | Implied Valuation from Raise | Implied | $16M | Strong Confidence |
| 82 | GrayMatters Health | PTSD neurofeedback treatment platform | $35M–$55M | Low Confidence | Implied Valuation from Raise | Implied | $10M | Strong Confidence |
| 83 | Monument | Online alcohol-use treatment | $35M–$52M | Partial Confidence | Comparables-Based Estimate | Estimated | $24M | Partial Confidence |
| 84 | Clerkenwell Health | Psychedelic clinical-trial services | $25M–$45M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $3M | Strong Confidence |
| 85 | Happify Health / Twill | Digital therapeutic care platform | $34M | Strong Confidence | Acquisition Value | Observed | $122M | Partial Confidence |
| 86 | Akili Interactive | Prescription digital therapeutic games | $34M | Full Confidence | Acquisition Value | Observed | $230M | Partial Confidence |
| 87 | Manatee | Digital family mental healthcare | $25M–$40M | Low Confidence | Comparables-Based Estimate | Estimated | $9M | Partial Confidence |
| 88 | Psyomics | AI mental health assessment software | $25M–$38M | Partial Confidence | Implied Valuation from Raise | Implied | $17M | Partial Confidence |
| 89 | ieso | Digital CBT therapy | $25M–$35M | Partial Confidence | Acquisition Value | Estimated | $77M | Partial Confidence |
| 90 | OxfordVR | Automated VR psychological therapy | $20M–$35M | Low Confidence | Acquisition Value | Estimated | $19M | Strong Confidence |
| 91 | Small Pharma | Short-duration psychedelic therapeutics | $24M | Strong Confidence | Acquisition Value | Observed | $49M | Partial Confidence |
| 92 | Woebot Health | AI mental health chatbot | $5M–$25M | Low Confidence | Proxy-Based Estimate | Estimated | $124M | Partial Confidence |
| 93 | Innerwell | Psychedelic-assisted therapy platform | $10M–$20M | Low Confidence | Implied Valuation from Raise | Implied | $3M | Full Confidence |
| 94 | Sonara Health | Remote methadone adherence monitoring | $8M–$16M | Low Confidence | Proxy-Based Estimate | Estimated | $6M | Partial Confidence |
| 95 | Numinus | Psychedelic-assisted therapy clinics | $5M–$15M | Low Confidence | Proxy-Based Estimate | Estimated | $50M | Partial Confidence |
| 96 | DynamiCare Health | Addiction recovery rewards platform | $7M–$12M | Low Confidence | Proxy-Based Estimate | Estimated | $6M | Full Confidence |
| 97 | Awakn Life Sciences | Addiction-focused psychedelic therapeutics | $3M–$6M | Partial Confidence | Acquisition Value | Implied | $14M | Partial Confidence |
| 98 | Braxia Scientific | Ketamine clinics and research | $0M–$2M | Low Confidence | Proxy-Based Estimate | Estimated | $2M | Low Confidence |

This chart, featured in our mental health market deck, compares the 2026 size of the mental health market with other markets of similar size
Key valuation trends in the mental health market
Insights
- Spring Health, MindMed and Lyra Health represent approximately $18.7 billion in combined midpoint valuation, equal to more than one-third of the value tracked across the mental health startup ranking.
- The top 10 mental health startups capture about 62.8% of the dataset’s total valuation, showing that sector value remains concentrated in a small group of scaled platforms and drug developers.
- Spring Health and Lyra Health carry a combined midpoint valuation of approximately $12.3 billion, which shows how strongly investors value employer-funded mental health distribution and recurring enterprise contracts.
- Headway’s midpoint valuation is more than ten times its disclosed funding, while Grow Therapy’s ratio reaches approximately 30 times, highlighting the capital efficiency of insurance-connected therapy marketplaces.
- MindMed alone is valued above Compass Pathways, atai Life Sciences, Bright Minds Biosciences and Cybin combined, showing how concentrated public psychedelic valuations have become.
- Eleos Health’s estimated $550 million midpoint valuation is more than four times its funding, suggesting that behavioral health AI creates greater value when embedded in clinical workflows rather than sold as a general wellness chatbot.
- Ophelia, Boulder Care and Bicycle Health support approximately $610 million in combined midpoint valuation, showing that specialized opioid-treatment platforms can reach meaningful scale without offering every category of mental healthcare.
- Affect Therapeutics has a midpoint valuation near $215 million against only $22 million raised, producing one of the strongest valuation-to-funding ratios in the addiction-care segment.
- Several acquired digital therapeutics businesses produced weak outcomes. Akili Interactive and Happify Health were acquired for a combined $68 million after raising approximately $352 million.
- The median startup in this ranking is valued at approximately $158 million, while the leading company’s midpoint valuation is more than 41 times higher, reflecting the mental health market’s unusually wide range of outcomes.

This chart, featured in our mental health market deck, shows why Talkspace is winning in mental health
A few word about our methodology
As you can see, we built a database that ranks startups in the mental health market based on their current valuation.
Estimating mental health startup valuations is not always straightforward. Many companies do not publicly disclose their valuation, and the available information can vary widely depending on the company, business model and development stage.
To build this ranking, we applied a structured valuation methodology and cross-checked information across multiple reliable sources.
Whenever possible, we relied on direct disclosures. These include announced valuations from completed funding rounds, public filings for listed mental health companies or official acquisition prices.
When a mental health company is publicly listed, we use its current market capitalization as the reference valuation.
If a company was acquired and no independent valuation can reasonably be estimated today, we use the acquisition price as the main reference point.
When a startup recently raised capital but the valuation was not disclosed, we estimate the implied valuation using typical dilution levels for that stage of fundraising.
In some cases, we also estimate valuations using operating metrics such as revenue, ARR, covered lives, patient volume or customer traction. We combine these metrics with valuation multiples from comparable mental health companies.
For clinical-stage biotechnology companies, we may also consider the maturity of the drug pipeline, trial results, addressable patient populations, licensing transactions and valuations of comparable neuropsychiatric developers.
For care-delivery platforms, we examine reimbursement coverage, payer relationships, clinician capacity, patient retention and the ability to serve clearly defined populations.
When direct financial data is not available, we may rely on carefully selected comparable startups and other signals such as hiring growth, investor quality, payer contracts, regulatory progress or product traction.
All estimates follow a strict evidence hierarchy. Recent funding rounds with announced valuations carry the most weight, followed by strong operating metrics and comparable company analysis.
We also carefully evaluate the age of every data point. Recent information carries more weight, while older data is treated cautiously and adjusted conservatively when necessary.
Whenever information is uncertain or incomplete, we clearly distinguish between confirmed facts and reasonable inferences.
Because valuation data is not always fully public, each mental health startup in the ranking is assigned a confidence level based on the reliability, recency and consistency of the available evidence.
Full confidence means the valuation is supported by strong and recent evidence. Strong confidence means the estimate is well supported but includes minor inference. Partial confidence means the estimate relies more heavily on indirect signals. Low confidence means available information is limited or inconsistent.
When confidence is lower, we take a more conservative approach by widening the valuation range. This helps reflect the uncertainty and increases the probability that the true valuation falls within the estimated range.
This reflects how we conduct all our research, including the work behind our report covering the mental health market.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific valuation estimate, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.

This chart, featured in our mental health market deck, illustrates yearly funding for mental health startups
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- The main fundraising trends in the mental health market
- How big is the mental health market really?
- The full range of business models in the mental health market
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