What are the most valued startups in the mental health market?
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In our mental health market deck, you will find everything you need to understand the market
The mental health market is now one of the most important categories in digital health, care delivery, behavioral health infrastructure, and neuropsychiatric innovation.
We update this list every month to keep the ranking fresh as new funding rounds, public market changes, acquisitions, and valuation estimates become available.
This ranking focuses on startups and growth companies in the mental health market, ordered by their latest reported or estimated valuations.
And if you want to better understand this new industry, you can download our pitch covering the mental health market.
A quick summary table
| Metric | Value |
|---|---|
| Most valuable mental health startup | Lyra Health |
| Second most valuable mental health startup | Spring Health |
| Median mental health startup valuation | About $215M |
| Share of total mental health valuation captured by the top 10 | About 54% |
| Top mental health startup valuation vs. median | About 26.7x |
| Median mental health valuation-to-capital-raised ratio | About 3.2x |
| Mental health startups valued at $1B+ | 12 based on valuation midpoint |

This market map, featured in our mental health market deck, highlights top companies and startups in the mental health market
Top startups in the mental health market ranked by valuation
Here is an updated table that ranks the top startups in the mental health market based on their latest reported or estimated valuations.
If you want more detaild about their fundraising activity, you can check our list of the startups who have raised the most funding in the mental health market.
| # | Startup Name | What They Do | Current Valuation ($) | Valuation Confidence Level | Valuation Type | Evidence Status | Total Funding ($) | Funding Confidence Level |
|---|---|---|---|---|---|---|---|---|
| 1 | Lyra Health | Employer mental health benefits | $5.0B–$6.5B | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $915M | Strong Confidence |
| 2 | Spring Health | Employer mental health platform | $3.0B–$3.8B | Strong Confidence | Announced Private Round Valuation | Estimated | $467M | Strong Confidence |
| 3 | Grow Therapy | Therapist marketplace and insurance | $3.0B | Full Confidence | Announced Private Round Valuation | Observed | $300M | Partial Confidence |
| 4 | Charlie Health | Virtual high-acuity youth care | $2.4B–$3.6B | Partial Confidence | Implied Valuation from Raise | Estimated | $404M | Partial Confidence |
| 5 | Headway | Therapist insurance network | $2.1B–$2.7B | Strong Confidence | Announced Private Round Valuation | Estimated | $326M | Strong Confidence |
| 6 | Talkiatry | In-network psychiatric care | $1.4B–$2.6B | Partial Confidence | Implied Valuation from Raise | Implied | $400M+ | Partial Confidence |
| 7 | MindMed | Psychedelic brain-health therapeutics | $1.5B–$1.9B | Strong Confidence | Public Market Cap | Observed | $685M | Partial Confidence |
| 8 | Compass Pathways | Psychedelic mental health therapeutics | $1.5B | Full Confidence | Public Market Cap | Observed | $864M | Partial Confidence |
| 9 | atai Life Sciences | Psychedelic mental-health biotech | $1.5B | Full Confidence | Public Market Cap | Observed | $624M | Strong Confidence |
| 10 | Cerebral | Online mental health care | $800M–$1.6B | Low Confidence | Proxy-Based Estimate | Estimated | $462M | Full Confidence |
| 11 | Cognito Therapeutics | Alzheimer’s neurostimulation device | $700M–$1.3B | Partial Confidence | Implied Valuation from Raise | Implied | $233M | Partial Confidence |
| 12 | SonderMind | Therapy marketplace and care | $800M–$1.2B | Low Confidence | Comparables-Based Estimate | Estimated | $183M | Strong Confidence |
| 13 | Draig Therapeutics | Neuropsychiatric drug development | $700M–$1.2B | Partial Confidence | Implied Valuation from Raise | Implied | $140M | Partial Confidence |
| 14 | Alma | Therapist insurance network | $700M–$1.1B | Partial Confidence | Comparables-Based Estimate | Estimated | $221M | Full Confidence |
| 15 | Talkspace | Online therapy marketplace | $870M | Full Confidence | Public Market Cap | Observed | $359M | Partial Confidence |
| 16 | Cortica | Whole-child autism care provider | $533M–$1.0B | Partial Confidence | Implied Valuation from Raise | Implied | $255M | Strong Confidence |
| 17 | Bright Minds Biosciences | Serotonergic drug discovery biotech | $675M–$750M | Strong Confidence | Public Market Cap | Observed | $56M | Partial Confidence |
| 18 | Author Health | Medicare serious mental healthcare | $450M–$750M | Partial Confidence | Implied Valuation from Raise | Estimated | $115M | Full Confidence |
| 19 | Eleos Health | Behavioral health AI documentation | $450M–$750M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $126M | Strong Confidence |
| 20 | Pelago | Virtual substance-use treatment | $390M–$650M | Partial Confidence | Implied Valuation from Raise | Implied | $151M | Partial Confidence |
| 21 | Two Chairs | Hybrid therapy provider network | $350M–$650M | Partial Confidence | Implied Valuation from Raise | Estimated | $100M | Partial Confidence |
| 22 | Brightline | Pediatric behavioral telehealth | $300M–$600M | Low Confidence | Proxy-Based Estimate | Estimated | $205M | Strong Confidence |
| 23 | Click Therapeutics | Prescription digital therapeutics software | $350M–$550M | Partial Confidence | Implied Valuation from Raise | Implied | $119M+ | Partial Confidence |
| 24 | NOCD | OCD-specialized virtual therapy | $300M–$550M | Partial Confidence | Comparables-Based Estimate | Estimated | $84M | Strong Confidence |
| 25 | Workit Health | Virtual addiction care | $320M–$500M | Partial Confidence | Announced Private Round Valuation | Estimated | $136M | Partial Confidence |
| 26 | Wayspring | Value-based SUD care platform | $300M–$500M | Partial Confidence | Implied Valuation from Raise | Implied | $161M | Strong Confidence |
| 27 | Gilgamesh Pharmaceuticals | Neuropsychiatric drug developer | $300M–$500M | Partial Confidence | Implied Valuation from Raise | Implied | $126M | Partial Confidence |
| 28 | AnswersNow | Virtual ABA autism therapy | $267M–$500M | Strong Confidence | Implied Valuation from Raise | Implied | $53M | Partial Confidence |
| 29 | Forta | AI-assisted autism therapy | $275M–$458M | Partial Confidence | Implied Valuation from Raise | Implied | $55M | Full Confidence |
| 30 | Concert Health | Collaborative care behavioral group | $275M–$475M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $56M | Partial Confidence |
| 31 | Lykos Therapeutics | MDMA-assisted PTSD therapy developer | $250M–$450M | Partial Confidence | Implied Valuation from Raise | Implied | $150M+ | Strong Confidence |
| 32 | Octave | In-network therapy services | $250M–$450M | Partial Confidence | Implied Valuation from Raise | Estimated | $86M | Strong Confidence |
| 33 | Tava Health | Employer mental health platform | $270M–$420M | Strong Confidence | Implied Valuation from Raise | Implied | $73M | Full Confidence |
| 34 | Cartwheel Care | School-based youth mental healthcare | $260M–$420M | Strong Confidence | Implied Valuation from Raise | Implied | $55M | Strong Confidence |
| 35 | Brightside Health | Virtual psychiatry and therapy care | $225M–$425M | Partial Confidence | Implied Valuation from Raise | Estimated | $114M | Full Confidence |
| 36 | Mindbloom | At-home ketamine therapy | $220M–$360M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $50M | Low Confidence |
| 37 | NeuroFlow | Behavioral health integration platform | $200M–$375M | Partial Confidence | Comparables-Based Estimate | Estimated | $55M | Strong Confidence |
| 38 | Ophelia | Telehealth opioid addiction treatment | $230M–$320M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $68M | Full Confidence |
| 39 | Holmusk | Behavioral health real-world data | $180M–$350M | Partial Confidence | Comparables-Based Estimate | Estimated | $109M | Partial Confidence |
| 40 | InStride Health | Pediatric anxiety/OCD care | $190M–$340M | Partial Confidence | Implied Valuation from Raise | Implied | $56M | Full Confidence |
| 41 | Affect Therapeutics | Digital SUD treatment clinic | $170M–$325M | Partial Confidence | Implied Valuation from Raise | Implied | $49M | Strong Confidence |
| 42 | Bicycle Health | Virtual opioid addiction treatment | $190M–$300M | Strong Confidence | Implied Valuation from Raise | Implied | $103M | Strong Confidence |
| 43 | Amae Health | Severe mental illness clinics | $180M–$310M | Strong Confidence | Implied Valuation from Raise | Implied | $50M+ | Partial Confidence |
| 44 | Valera Health | High-acuity virtual mental healthcare | $160M–$320M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $74M | Partial Confidence |
| 45 | Array Behavioral Care | Virtual psychiatry and therapy | $180M–$300M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $49M | Partial Confidence |
| 46 | Eleanor Health | Addiction and mental health care | $180M–$300M | Partial Confidence | Implied Valuation from Raise | Implied | $164M | Partial Confidence |
| 47 | Big Health | FDA-cleared digital therapeutics | $160M–$300M | Partial Confidence | Implied Valuation from Raise | Implied | $153M | Full Confidence |
| 48 | Delix Therapeutics | Non-hallucinogenic neuroplastogen drugs | $150M–$300M | Partial Confidence | Comparables-Based Estimate | Estimated | $100M | Strong Confidence |
| 49 | Cybin | Psychedelic neuropsychiatry drug developer | $208M–$228M | Strong Confidence | Public Market Cap | Observed | $451M | Strong Confidence |
| 50 | firsthand | Serious mental illness peer support | $150M–$280M | Partial Confidence | Implied Valuation from Raise | Estimated | $43M | Partial Confidence |
| 51 | Freespira | Breathing-based anxiety digital therapeutic | $150M–$280M | Partial Confidence | Implied Valuation from Raise | Implied | $48M | Strong Confidence |
| 52 | Uwill | College mental health platform | $160M–$260M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $39M | Full Confidence |
| 53 | ieso | AI-enabled digital CBT | $125M–$275M | Low Confidence | Comparables-Based Estimate | Estimated | $77M | Partial Confidence |
| 54 | Brave Health | Medicaid virtual behavioral care | $140M–$260M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $60M | Strong Confidence |
| 55 | Boulder Care | Virtual addiction medicine care | $160M–$230M | Partial Confidence | Comparables-Based Estimate | Estimated | $85M | Strong Confidence |
| 56 | PursueCare | Telehealth addiction treatment platform | $120M–$220M | Partial Confidence | Implied Valuation from Raise | Implied | $31M | Strong Confidence |
| 57 | Bend Health | Pediatric family mental healthcare | $120M–$220M | Partial Confidence | Acquisition Value | Estimated | $32M | Strong Confidence |
| 58 | Osmind | Neuropsychiatry EHR and research | $110M–$225M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $57M | Full Confidence |
| 59 | Beckley Psytech | Short-duration psychedelic medicines | $125M–$180M | Partial Confidence | Announced Private Round Valuation | Implied | $142M | Strong Confidence |
| 60 | Meru Health | Digital depression-anxiety care | $110M–$190M | Low Confidence | Comparables-Based Estimate | Estimated | $42M | Partial Confidence |
| 61 | HelloSelf | Digital therapy and coaching | $100M–$180M | Partial Confidence | Implied Valuation from Raise | Estimated | $28M | Strong Confidence |
| 62 | Iris Telehealth | Telepsychiatry for health systems | $90M–$160M | Partial Confidence | Implied Valuation from Raise | Implied | $40M | Partial Confidence |
| 63 | aptihealth | Higher-acuity behavioral healthcare | $80M–$160M | Low Confidence | Implied Valuation from Raise | Estimated | $63M | Partial Confidence |
| 64 | Ria Health | Telehealth alcohol-use treatment | $85M–$155M | Partial Confidence | Implied Valuation from Raise | Implied | $25M | Partial Confidence |
| 65 | SpectrumAi | Autism-care analytics platform | $80M–$160M | Partial Confidence | Acquisition Value | Estimated | $29M | Full Confidence |
| 66 | Blackbird Health | Youth neuroscience-led mental healthcare | $90M–$145M | Strong Confidence | Implied Valuation from Raise | Implied | $23M | Strong Confidence |
| 67 | Mantra Health | College mental health clinic | $80M–$140M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $32M | Strong Confidence |
| 68 | BehaVR | VR behavioral health therapeutics | $80M–$140M | Partial Confidence | Comparables-Based Estimate | Estimated | $21M | Strong Confidence |
| 69 | Quartet Health | Behavioral health care coordination | $50M–$150M | Low Confidence | Acquisition Value | Estimated | $222M | Partial Confidence |
| 70 | Backpack Healthcare | Medicaid pediatric mental healthcare | $75M–$125M | Strong Confidence | Implied Valuation from Raise | Implied | $14M | Strong Confidence |
| 71 | Flow Neuroscience | Depression brain stimulation headset | $70M–$120M | Partial Confidence | Revenue or ARR Multiple Estimate | Estimated | $12M | Strong Confidence |
| 72 | Neuronetics | Depression neurostimulation devices | $89M | Full Confidence | Public Market Cap | Observed | $272M | Partial Confidence |
| 73 | Marigold Health | Peer recovery support technology | $55M–$90M | Strong Confidence | Implied Valuation from Raise | Implied | $17M | Strong Confidence |
| 74 | Birches Health | Gambling addiction treatment | $55M–$85M | Strong Confidence | Implied Valuation from Raise | Implied | $20M | Strong Confidence |
| 75 | Opya | Early autism intervention services | $45M–$90M | Low Confidence | Comparables-Based Estimate | Estimated | $15M | Partial Confidence |
| 76 | GrayMatters Health | PTSD neuromodulation therapeutics | $45M–$80M | Partial Confidence | Implied Valuation from Raise | Estimated | $10M | Full Confidence |
| 77 | Journey Clinical | Ketamine-assisted clinician network | $40M–$75M | Partial Confidence | Implied Valuation from Raise | Implied | $12M | Strong Confidence |
| 78 | Healios | Digital autism mental healthcare | $45M–$70M | Strong Confidence | Announced Private Round Valuation | Observed | $53M | Partial Confidence |
| 79 | Fort Health | Pediatric primary-care mental health | $35M–$70M | Partial Confidence | Implied Valuation from Raise | Implied | $16M | Partial Confidence |
| 80 | OxfordVR | Automated VR therapy | $30M–$60M | Partial Confidence | Acquisition Value | Estimated | $19M | Strong Confidence |
| 81 | Little Otter | Family mental health care | $25M–$60M | Low Confidence | Acquisition Value | Estimated | $36M | Strong Confidence |
| 82 | Psylo | Next-generation neuroplastogen medicines | $32M–$53M | Partial Confidence | Implied Valuation from Raise | Implied | $14M | Strong Confidence |
| 83 | Manatee | Virtual family therapy | $30M–$55M | Partial Confidence | Implied Valuation from Raise | Estimated | $12M | Partial Confidence |
| 84 | Monument | Online alcohol treatment program | $25M–$55M | Low Confidence | Comparables-Based Estimate | Estimated | $24M | Partial Confidence |
| 85 | Psyomics | AI mental health assessment | $27M–$45M | Strong Confidence | Implied Valuation from Raise | Implied | $17M | Strong Confidence |
| 86 | Nue Life Health | At-home ketamine therapy | $20M–$50M | Low Confidence | Acquisition Value | Estimated | $28M | Partial Confidence |
| 87 | Akili Interactive | Cognitive digital therapeutics | $34M–$35M | Strong Confidence | Acquisition Value | Observed | $383M | Partial Confidence |
| 88 | Happify Health | Digital mental wellness platform | $30M | Strong Confidence | Acquisition Value | Observed | $122M | Partial Confidence |
| 89 | Magstim | TMS neurostimulation devices | $20M–$40M | Low Confidence | Revenue or ARR Multiple Estimate | Estimated | $32M | Low Confidence |
| 90 | Small Pharma | DMT-based psychedelic therapeutics | $22M–$24M | Strong Confidence | Acquisition Value | Observed | $49M | Partial Confidence |
| 91 | As You Are | Virtual autism evaluations | $10M–$30M | Low Confidence | Proxy-Based Estimate | Estimated | $0M | Low Confidence |
| 92 | Innerwell | Psychedelic-assisted mental healthcare | $8M–$18M | Low Confidence | Proxy-Based Estimate | Estimated | $3M | Full Confidence |
| 93 | Clerkenwell Health | Psychedelic clinical research organization | $8M–$18M | Low Confidence | Implied Valuation from Raise | Implied | $2M | Full Confidence |
| 94 | Numinus | Psychedelic-assisted therapy clinics | $10M–$15M | Partial Confidence | Public Market Cap | Observed | $34M | Partial Confidence |
| 95 | DynamiCare Health | Addiction recovery digital therapeutics | $8M–$15M | Low Confidence | Proxy-Based Estimate | Estimated | $6M | Partial Confidence |
| 96 | Sonara Health | Hybrid methadone treatment platform | $7M–$13M | Low Confidence | Implied Valuation from Raise | Implied | $4M | Partial Confidence |
| 97 | Awakn Life Sciences | Addiction-focused psychedelic therapeutics | $6M–$7M | Strong Confidence | Acquisition Value | Observed | $12M | Partial Confidence |
| 98 | Woebot Health | AI mental health chatbot | $0M–$10M | Low Confidence | Proxy-Based Estimate | Estimated | $124M | Strong Confidence |
| 99 | Braxia Scientific | Ketamine clinics and research | $0M–$1M | Low Confidence | Public Market Cap | Observed | $12M | Low Confidence |

This chart, featured in our mental health market deck, compares the 2026 size of the mental health market with other markets of similar size
Key valuation trends in the mental health market
Insights
- The mental health market is highly concentrated, with the top 10 companies representing about 54% of total valuation across this dataset.
- Lyra Health is almost 27 times larger than the median mental health startup by valuation, which shows how far the category leader has pulled ahead.
- Employer and access platforms still capture the biggest valuation premiums, with Lyra Health, Spring Health, Headway, and Tava Health forming a large part of the private platform value pool.
- Pediatric and youth mental health companies are becoming a meaningful category, especially Charlie Health, Cartwheel Care, Blackbird Health, and Backpack Healthcare.
- Public psychedelic and neuropsychiatry companies have raised large amounts of capital, but valuation efficiency remains weaker than in care delivery and access infrastructure.
- Substance-use care platforms are important, but the category’s valuation-to-funding profile is lower than youth care and employer mental health platforms.

This chart, featured in our mental health market deck, shows why Talkspace is winning in mental health
A few word about our methodology
As you can see, we built a database that ranks startups in the mental health market based on their current valuation.
Estimating startup valuations is not always straightforward. Many companies do not publicly disclose their valuation, and the available information can vary widely depending on the company and its stage.
To build this ranking, we applied a structured valuation methodology and cross-checked information across multiple reliable sources.
Whenever possible, we relied on direct disclosures. These include announced valuations from completed funding rounds, public filings for listed companies, or official acquisition prices.
When a mental health startup is publicly listed, we use its current market capitalization as the reference valuation.
If a mental health company was acquired and no independent valuation can reasonably be estimated today, we use the acquisition price as the main reference point.
When a startup recently raised capital but the valuation was not disclosed, we estimate the implied valuation using typical dilution levels for that stage of fundraising.
In some cases, we also estimate valuations using operating metrics such as revenue, ARR, covered lives, provider network size, patient volume, or customer traction, combined with valuation multiples from comparable companies in the same market.
When direct financial data is not available, we may rely on carefully selected comparable startups and other signals such as hiring growth, investor quality, product traction, payer relationships, clinical footprint, or public market benchmarks.
All estimates follow a strict evidence hierarchy. Recent funding rounds with announced valuations carry the most weight, followed by strong operating metrics and comparable company analysis.
We also carefully evaluate the age of every data point. Recent information carries more weight, while older data is treated cautiously and adjusted conservatively when necessary.
Whenever information is uncertain or incomplete, we clearly distinguish between confirmed facts and reasonable inferences.
Because valuation data is not always fully public, each startup in the ranking is assigned a confidence level based on the reliability, recency, and consistency of the available evidence.
Full confidence means the valuation is supported by strong and recent evidence. Strong confidence means the estimate is well supported but includes minor inference. Partial confidence means the estimate relies more heavily on indirect signals. Low confidence means available information is limited or inconsistent.
When confidence is lower, we take a more conservative approach by widening the valuation range. This helps reflect the uncertainty and increases the probability that the true valuation falls within the estimated range.
This reflects how we conduct all our research, including the work behind our report covering the mental health market.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific valuation estimate, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.

This chart, featured in our mental health market deck, illustrates yearly funding for mental health startups
Related blog posts
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- What is new in the mental health market lately?
- The evolution of funding activity in the mental health market
- The main fundraising trends in the mental health market
- How big is the mental health market really?
- The full range of business models in the mental health market
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