Which startups have raised the most funding in the synthetic biology market?
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In our synthetic biology market deck, you will find everything you need to understand the market
The synthetic biology market is one of the most capital-intensive areas in biotech, with large funding totals across biofoundries, precision fermentation, gene editing, cell therapy, and engineered materials.
This list ranks the top synthetic biology startups by cumulative funding raised, and we update it every month to keep the data fresh.
The ranking shows a market shaped by a few very large platforms, while dozens of smaller companies keep building in food, chemicals, therapeutics, DNA synthesis, and lab automation.
And if you want to better understand this new industry, you can download our pitch covering the synthetic biology market.
A quick summary table
| Metric | Value |
|---|---|
| Most funded startup | Ginkgo Bioworks, $2.5B raised |
| Second most funded startup | Impossible Foods, $2.0B raised |
| Largest funding round | Ginkgo Bioworks, $1.6B SPAC PIPE in September 2021 |
| Median funding | About $100.5M across the full ranked dataset |
| Share of funding captured by the top 10 | About 59% of the cleaner funding pool |
| Median time since last round | About 3 years since the latest disclosed round |
| Startups that raised funding in the last 12 months | 16 companies raised funding between July 2025 and July 2026 |
| Synthetic biology billion-dollar funding club | 5 startups have raised at least $1.0B |
| Precision fermentation funding leaders | Perfect Day, The EVERY Company, Geltor, Remilk, Formo, and Verley lead the segment |
| Therapeutics synthetic biology capital pool | Generate Biomedicines, ArsenalBio, Tessera, Senti, and Obsidian raised about $3.2B combined |

This chart, featured in our synthetic biology market deck, illustrates yearly VC funding for synthetic biology startups
Top startups in the synthetic biology market ranked by total funding raised
Here is an updated table that ranks the top startups in the synthetic biology market based on the total amount of funding they have raised to date.
The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected (we excluded startups with very low data confidence, to make sure everything is reliable).
If you're interested in knowing how much these startups are worth, you can check our list of the top startups in the synthetic biology market ranked by valuation.
| # | Startup | What They Do | Total Raised ($) | Total Rounds | Last Round Date | Last Round Amount ($) | Last Round Type | Key Investors | Current Stage | Confidence |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Ginkgo Bioworks | Bio platform company | $2.5B | 6+ | September 2021 | $1.6B | SPAC PIPE | SoftBank, ARK, Viking | IPO | Strong |
| 2 | Impossible Foods | Plant-based meat | $2.0B | 6 | March 2020 | $500M | Series E | Temasek, Coatue | Active | Strong |
| 3 | Amyris | Synthetic chemicals | $1.2B | 6+ | 2022 | $400M | Late-stage equity | Temasek, BP | Shutdown | Strong |
| 4 | Generate Biomedicines | AI-designed protein therapeutics | $1.1B | 5 | February 2026 | $400M | IPO | Flagship Pioneering, Amgen, NVentures | IPO | Strong |
| 5 | Perfect Day | Animal-free dairy proteins | $1.0B | 5 | September 2021 | $350M | Series D | CPP Investments, Temasek | Active | Strong |
| 6 | Zymergen | Bio materials company | $900M | 5 | September 2020 | $300M | Series E | SoftBank, Temasek | Acquired | Strong |
| 7 | ArsenalBio | Programmable cancer cell therapies | $630M | 3 | September 2024 | $325M | Series C | ARCH Venture Partners, Regeneron Ventures, NVentures | Active | Full |
| 8 | Tessera Therapeutics | Gene writing therapeutics | $610M | 3 | April 2022 | $300M | Series C | ADIA, Alaska Permanent Fund, Flagship Pioneering | Active | Strong |
| 9 | Solugen | Green chemicals | $600M | 4 | 2023 | $200M | Extension | Temasek, GIC | Active | Strong |
| 10 | Pivot Bio | Microbial ag inputs | $600M | 5 | 2023 | $50M | Extension | Gates, DCVC | Active | Strong |
| 11 | Senti Biosciences | Gene circuit cell therapies | $502M | 4 | January 2025 | $48M | Post-IPO PIPE | Celadon Partners, NEA, Leaps by Bayer | IPO | Strong |
| 12 | Bolt Threads | Bio textiles | $500M | 5 | June 2021 | $250M | Series D | SoftBank, Temasek | Active | Strong |
| 13 | Inscripta | Digital genome engineering platform | $495M | 9 | December 2022 | $28M | Late-stage extension | Fidelity, T. Rowe Price, Foresite Capital | Acquired | Partial |
| 14 | Spiber | Fermented protein textile materials | $491M | 8 | April 2024 | $65M | Series E | The Carlyle Group, Fidelity Investments, Baillie Gifford | Active | Strong |
| 15 | Synthego | CRISPR genome engineering tools | $460M | 7 | February 2022 | $200M | Series E | Perceptive Advisors, SoftBank Vision Fund 2, RA Capital | Acquired | Strong |
| 16 | Benchling | Biotech SaaS | $420M | 4 | 2022 | $75M | Series D | Sequoia, Benchmark | Active | Strong |
| 17 | Genomatica / Geno | Bio-based chemicals and materials | $388M | 8 | August 2021 | Undisclosed | Strategic equity | Novo Holdings, Casdin Capital, Viking Global Investors | Active | Partial |
| 18 | Motif FoodWorks | Plant-based ingredient biotechnology | $344M | 4 | May 2022 | Undisclosed | Series B extension | Ontario Teachers’ Pension Plan, BlackRock, General Atlantic | Shutdown | Full |
| 19 | Obsidian Therapeutics | Engineered cell therapies | $326M | 3 | April 2024 | $161M | Series C | Wellington Management, Novo Holdings, Logos Capital | Active | Strong |
| 20 | DNA Script | Enzymatic DNA printing platform | $315M | 4 | January 2022 | $200M | Series C | Coatue, Catalio, T. Rowe Price | Active | Strong |
| 21 | Arbor Biotechnologies | CRISPR genetic medicine platform | $305M | 3 | March 2025 | $74M | Series C | ARCH Venture Partners, TCGX, Abrdn | Active | Partial |
| 22 | Twist Bioscience | DNA synthesis | $300M | 4 | October 2017 | $100M | Series D | Baillie Gifford, Fidelity | IPO | Strong |
| 23 | The EVERY Company | Animal-free egg proteins | $287M | 5 | November 2025 | $55M | Series D | McWin Capital Partners, Main Sequence, Bloom8 | Active | Strong |
| 24 | Opentrons | Automated lab robotics platform | $271M | 18 | December 2025 | $20M | Series C-II | SoftBank Vision Fund 2, Khosla Ventures, Y Combinator | Active | Partial |
| 25 | Mammoth Biosciences | CRISPR therapeutics and diagnostics | $263M | 5 | September 2021 | $150M | Series D | Redmile Group, Foresite Capital, Sixth Street | Active | Strong |
| 26 | Chroma Medicine | Epigenetic editing medicines | $260M | 3 | March 2023 | $135M | Series B | GV, ARCH Venture Partners, Sixth Street | Active | Strong |
| 27 | bit.bio | Programmed human cell products | $233M | 5 | January 2026 | $50M | Series C | M&G Investments, ARCH Venture Partners, Tencent | Active | Partial |
| 28 | Tune Therapeutics | Epigenome editing therapeutics | $215M | 2 | January 2025 | $175M | Series B | NEA, Yosemite, Regeneron Ventures | Active | Full |
| 29 | Strand Therapeutics | Programmable mRNA therapeutics | $211M | 3 | August 2025 | $153M | Series B | Kinnevik, Regeneron Ventures, ICONIQ | Active | Partial |
| 30 | Asimov | Genetic design and manufacturing platform | $205M | 3 | January 2023 | $175M | Series B | CPP Investments, Fidelity, Casdin Capital | Active | Strong |
| 31 | MycoWorks | Mycelium leather materials | $187M | 3 | January 2022 | $125M | Series C | Prime Movers Lab, DCVC Bio, Novo Holdings | Active | Partial |
| 32 | Hexagon Bio | Microbial genome drug discovery | $185M | 3 | February 2023 | $77M | Series B | The Column Group, Two Sigma Ventures, CPP Investments | Active | Partial |
| 33 | Modern Meadow | Biofabricated leather materials | $184M | 3 | April 2021 | $130M | Series C | Key Partners Capital, Astanor Ventures, Horizons Ventures | Active | Partial |
| 34 | Synlogic | Synthetic biotic medicines | $151M | 4 | June 2019 | $80M | Post-IPO PIPE | Ginkgo Bioworks | IPO | Partial |
| 35 | Profluent | AI protein design | $150M | 3 | November 2025 | $106M | Series B | Altimeter Capital, Bezos Expeditions, Spark Capital | Active | Full |
| 36 | EvolutionaryScale | AI protein generation | $142M | 1 | June 2024 | $142M | Seed | Nat Friedman, Daniel Gross, Lux Capital | Active | Full |
| 37 | Geltor | Animal-free collagen proteins | $137M | 5 | August 2025 | $21M | Equity financing | Starlight Ventures, iSelect Fund, Cultivian Sandbox | Active | Strong |
| 38 | Ansa Biotechnologies | Long DNA synthesis services | $132M | 4 | October 2025 | $54M | Series B | Cerberus Ventures, Northpond Ventures, RA Capital | Active | Strong |
| 39 | Ecovative | Mycelium materials platform | $131M | 5 | March 2025 | $11M | Series E / equity | Viking Global Investors, AiiM Partners, FootPrint Coalition Ventures | Active | Partial |
| 40 | Remilk | Animal-free dairy proteins | $131M | 2 | January 2022 | $120M | Series B | Hanaco Ventures, fresh.fund, OurCrowd | Active | Full |
| 41 | Debut | Biotech ingredients for beauty | $119M | 5 | August 2025 | $20M | Series B / venture | EDBI, BOLD, Material Impact | Active | Partial |
| 42 | Formo | Fermented dairy alternatives | $116M | 3 | September 2024 | $61M | Series B | EQT Ventures, Lowercarbon Capital, FoodLabs | Active | Full |
| 43 | Octant | Multiplexed drug discovery platform | $115M | 4 | April 2022 | $80M | Series B | Catalio Capital, Bristol Myers Squibb, a16z Bio | Active | Strong |
| 44 | Sherlock Biosciences | CRISPR molecular diagnostics | $111M | 2 | March 2022 | $80M | Series B | Novalis LifeSciences, Illumina Ventures, Catalio Capital Management | Acquired | Strong |
| 45 | Checkerspot | Fermented oils for biomaterials | $109M | 4 | February 2023 | $55M | Series C | ArrowMark Partners, Cox Enterprises, Viking Global | Active | Strong |
| 46 | AMSilk | Biofabricated silk proteins | $104M | 5 | September 2025 | $35M | Series D / mixed financing | ATHOS, MIG Capital, Novo Holdings | Active | Partial |
| 47 | Cradle | AI-powered protein engineering | $103M | 3 | November 2024 | $73M | Series B | IVP, Index Ventures, Kindred Capital | Active | Strong |
| 48 | Culture Biosciences | Cloud biomanufacturing platform | $101M | 4 | December 2025 | Undisclosed | Series C | Northpond Ventures, Synthesis Capital, S32 | Active | Strong |
| 49 | Nobell Foods / Alpine Bio | Molecular-farmed dairy proteins | $100M | 3 | July 2021 | $75M | Series B | Breakthrough Energy Ventures, Andreessen Horowitz, FootPrint Coalition | Active | Partial |
| 50 | Viridos | Algae biofuels platform | $100M | 4 | March 2023 | $25M | Series A | Breakthrough Energy Ventures, Chevron, United Airlines Ventures | Acquired | Partial |
| 51 | Strateos | Robotic cloud lab platform | $99M | 6 | June 2021 | $56M | Series B | DCVC, Lux Capital, Eli Lilly | Active | Partial |
| 52 | Cellino | Autonomous cell therapy manufacturing | $96M | 2 | January 2022 | $80M | Series A | Leaps by Bayer, 8VC, Humboldt Fund | Active | Strong |
| 53 | Arzeda | AI protein design enzymes | $91M | 4 | August 2025 | $5M | Equity, undisclosed stage | Sofinnova Partners, Conti Ventures, OS Fund | Active | Strong |
| 54 | GRO Biosciences | Expanded-code protein therapeutics | $87M | 3 | July 2024 | $60M | Series B | Atlas Venture, Access Biotechnology, Leaps by Bayer | Active | Partial |
| 55 | Basecamp Research | Biodiversity AI protein discovery | $85M | 3 | October 2024 | $60M | Series B | Singular, S32, redalpine | Active | Partial |
| 56 | Constructive Bio | Synthetic genomes and biomolecules | $75M | 3 | September 2024 | $58M | Series A | Ahren, OMX Ventures, Paladin Capital Group | Active | Strong |
| 57 | Synthace | Biology automation software | $73M | 4 | November 2021 | $35M | Series C | Horizons Ventures, Sofinnova Partners, SOSV | Active | Strong |
| 58 | Evonetix | Semiconductor DNA synthesis platform | $66M | 3 | February 2023 | $24M | Series B extension | Foresite Capital, DCVC, Molten Ventures | Active | Strong |
| 59 | Molecular Assemblies | Enzymatic DNA synthesis technology | $64M | 4 | March 2022 | $26M | Series B | Casdin Capital, iSelect Fund, Agilent Technologies | Active | Strong |
| 60 | 64x Bio | Cell lines for gene therapy | $60M | 3 | January 2022 | $55M | Series A | Lifeforce Capital, Northpond Ventures, First Round Capital | Active | Partial |
| 61 | Locus Biosciences | CRISPR phage antimicrobials | $59M | 3 | May 2022 | $35M | Series B | ARTIS Ventures, Viking Global Investors, JJDC | Active | Partial |
| 62 | Onego Bio | Animal-free egg proteins | $57M | 3 | July 2024 | $15M | Series A extension | EIC Fund, NordicNinja, Agronomics | Active | Partial |
| 63 | Catalog | DNA data storage computing | $54M | 3 | September 2021 | $35M | Series B | Hanwha Impact, Horizons Ventures, Airbus Ventures | Acquired | Strong |
| 64 | Eligo Bioscience | Microbiome gene editing | $53M | 3 | December 2023 | $30M | Series B | Sanofi Ventures, Bpifrance, Khosla Ventures | Active | Strong |
| 65 | Verley | Precision-fermented whey proteins | $50M | 3 | February 2026 | $30M | Series A | Alven, Blast, Sofinnova Partners | Active | Strong |
| 66 | Standing Ovation | Precision-fermented casein proteins | $45M | 3 | March 2026 | $29M | Series B | Bpifrance, Crédit Mutuel Innovation, Danone Ventures | Active | Strong |
| 67 | Colorifix | Biological textile dyeing | $44M | 3 | June 2025 | $18M | Series B2 | Inter IKEA Group, H&M Group, Cambridge Enterprise | Active | Strong |
| 68 | Lygos | Bio-based specialty chemicals | $41M | 4+ | February 2021 | Undisclosed | Strategic equity | IA Ventures, First Round Capital, LG Technology Ventures | Active | Partial |
| 69 | Emerald Cloud Lab | Remote automated cloud laboratory | $40M | 4 | June 2022 | Undisclosed | Series C preferred | Trinity Capital, WTI, Incite Ventures | Active | Low |
| 70 | TurtleTree | Cell-cultured dairy ingredients | $39M | 3 | November 2021 | $30M | Series A | VERSO Capital, Green Monday Ventures, KBW Ventures | Active | Strong |
| 71 | Shiru | AI-designed functional proteins | $37M | 3 | November 2024 | $16M | Series B | S2G Ventures, CPT Capital, Lux Capital | Active | Full |
| 72 | Vivici | Precision-fermented dairy proteins | $34M | 1 | February 2025 | $34M | Series A | APG / ABP, Invest-NL, InnovationQuarter | Active | Partial |
| 73 | Volta Labs | Genomics sample-prep automation | $33M | 2 | January 2024 | $13M | Series A-II | Maverick Ventures, Khosla Ventures, Casdin Capital | Active | Partial |
| 74 | All G | Precision-fermented dairy proteins | $30M | 2 | August 2022 | $18M | Series A | Agronomics, New Agrarian Company, CEFC | Active | Strong |
| 75 | New Culture | Animal-free cheese casein | $29M | 4 | November 2022 | Undisclosed | Strategic funding | CJ CheilJedang, Ahren Innovation Capital, CPT Capital | Active | Partial |
| 76 | Imagindairy | Animal-free milk proteins | $28M | 2 | May 2022 | $15M | Seed extension | Target Global, MoreVC, Strauss Group | Active | Strong |
| 77 | Rubi Laboratories | CO₂-to-materials enzymes | $26M | 4 | March 2026 | $8M | Undisclosed / Series A-like | AP Ventures, FH One Investments, H&M Group | Active | Partial |
| 78 | ZymoChem | Bio-based materials manufacturing | $25M | 2 | January 2024 | $21M | Series A | Breakout Ventures, lululemon, Toyota Ventures | Active | Strong |
| 79 | PILI | Bio-based dyes and pigments | $25M | 4 | February 2023 | $16M | Series A | Bpifrance, Famille C Participations, Elaia Partners | Active | Partial |
| 80 | Better Dairy | Animal-free dairy proteins | $24M | 2 | January 2022 | $22M | Series A | Redalpine, Vorwerk, Happiness Capital | Active | Full |
| 81 | String Bio | Methane-to-products biotechnology | $24M | 3 | July 2022 | $20M | Series B | Woodside Energy, Ankur Capital, Dare Ventures | Active | Full |
| 82 | Eden Brew | Animal-free dairy proteins | $23M | 3 | October 2023 | $15M | Series A | Main Sequence, Breakthrough Victoria, Orkla | Active | Strong |
| 83 | BioPhero | Fermented insect pheromones | $21M | 2 | March 2021 | $17M | Series A | DCVC Bio, FMC Ventures, Novo Holdings | Acquired | Full |
| 84 | Ribbon Biolabs | Long DNA synthesis technology | $20M | 2 | January 2022 | $20M | Series A | Hadean Ventures, Lansdowne Partners, Helicase Venture | Active | Strong |
| 85 | Liberation Labs | Precision fermentation manufacturing | $20M | 1 | December 2022 | $20M | Seed | Agronomics, Siddhi Capital, CPT Capital | Active | Partial |
| 86 | AlgiKnit / Keel Labs | Kelp-derived textile fibers | $17M | 4 | June 2022 | $13M | Series A | Collaborative Fund, H&M CO:LAB, Horizons Ventures | Active | Strong |
| 87 | Huue | Bio-based indigo dye | $17M | 2 | July 2022 | $15M | Series A | Material Impact, HSBC Climate Tech VC, SOSV | Active | Full |
| 88 | Tierra Biosciences | Cell-free custom protein synthesis | $17M | 3 | March 2024 | $11M | Series A | Material Impact, Prosus Ventures, In-Q-Tel | Active | Partial |
| 89 | Protera | AI protein design platform | $16M | 3 | July 2021 | $10M | Series A | Sofinnova Partners, Bimbo Group, ICL Planet | Active | Strong |
| 90 | Change Foods | Animal-free cheese proteins | $15M | 3 | February 2022 | $12M | Seed extension | Route 66 Ventures, Upfield, Blue Horizon Ventures | Active | Strong |
| 91 | Melt&Marble | Precision-fermented designer fats | $15M | 3 | December 2025 | $9M | Series A | Industrifonden, EIC Fund, Beiersdorf | Active | Full |
| 92 | Octarine Bio | Fermented sustainable pigments | $14M | 4 | January 2026 | $6M | Series A extension | The Footprint Firm, Unconventional Ventures, Oskare Capital | Active | Partial |
| 93 | Enduro Genetics | Bioproduction cell reprogramming | $12M | 2 | February 2025 | $12M | Series A | Supernova Invest, NOON Ventures, Sandwater | Active | Partial |
| 94 | Solena Materials | AI-designed protein fibers | $11M | 2 | May 2025 | $7M | Seed | Sir David Harding, SynBioVen, Insempra | Active | Full |
| 95 | Michroma | Fungi-based natural food colors | $7M | 3 | February 2023 | $6M | Seed | Supply Change Capital, Be8 Ventures, CJ CheilJedang | Active | Partial |
| 96 | Wild Microbes | Engineered microbes for biomanufacturing | $3M | 1 | February 2023 | $3M | Pre-seed | Climate Capital Bio, Freeflow, Agronomics | Active | Strong |
| 97 | TeselaGen | Synthetic biology design software | $2M | 1 | January 2018 | $2M | Seed | Baruch Future Ventures, undisclosed | Active | Low |
| 98 | Daisy Lab | Precision-fermented dairy proteins | $1M | 1 | March 2023 | $1M | Seed | The Values Trust, Icehouse Ventures, Outset Ventures | Active | Strong |

This market map, featured in our synthetic biology market deck, highlights top companies and startups in the synthetic biology market
Key funding trends in the synthetic biology market
Insights
- The top five synthetic biology startups raised about $7.8B combined, which shows how much capital is concentrated in a small group of platform companies.
- The top 10 synthetic biology companies account for about $11.1B, nearly 60% of the cleaner funding pool, so late-stage winners strongly shape market totals.
- Food, ingredients, and bio-based chemicals remain a major funding cluster, with Impossible Foods, Perfect Day, Solugen, Pivot Bio, and Motif FoodWorks totaling about $4.5B.
- Therapeutics-focused synthetic biology is gaining weight, with Generate Biomedicines, ArsenalBio, Tessera, Senti Biosciences, and Obsidian Therapeutics raising about $3.2B together.
- Scale-up risk is still very visible in synthetic biology, since Amyris and Motif FoodWorks absorbed about $1.5B before shutting down.
- AI-native biology is changing funding patterns, as EvolutionaryScale raised a $142M seed round, larger than the lifetime funding of many later-stage synthetic biology startups.
- Precision-fermentation dairy remains fragmented: Perfect Day dominates with $1.0B, while Formo, Remilk, Verley, Standing Ovation, and Better Dairy together raised about $366M.
- Strategic investors are highly active in synthetic biology, especially Temasek, SoftBank, ARCH, Flagship, Novo Holdings, and major pharma or food groups.

As this chart shows, and as featured in our synthetic biology market deck, search interest in gene editing has grown significantly
A few word about our methodology
As you can see, we built a database that ranks startups in the synthetic biology market based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.
Whenever possible, we prioritized official company communications, since company announcements are usually the most reliable source for synthetic biology funding amounts. When those were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times or Forbes (to name a few).
We excluded random blogs, unverified websites, and any sources that could not be validated.
When funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.
Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each synthetic biology startup, visible in the last column.
Here is what they mean.
Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.
Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.
Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.
Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.
When the confidence level is too low, we take a conservative approach and exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.
This reflects how we conduct all our research, including the work behind our report covering the synthetic biology market.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.

This chart, featured in our synthetic biology market deck, shows how Twist Bioscience is capturing share in synthetic biology
Related blog posts
- The most recent news in synthetic biology
- The most recent funding news in synthetic biology
- The latest changes in the synthetic biology market
- The evolution of funding activity in synthetic biology
- The main fundraising trends in synthetic biology
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