Which startups have raised the most funding in the longevity biotech market?

In our updated market reports, you will find everything you need
This article tracks the most funded startups in the longevity biotech market, ranked by cumulative funding raised.
We update this list every month, because longevity biotech funding changes quickly across private rounds, IPOs, acquisitions, and public-market financings.
The market is highly concentrated, with Altos Labs, Insilico Medicine, BioSplice Therapeutics, NewLimit, and BioAge Labs representing a large share of disclosed capital.
A quick summary table
| Metric | Value |
|---|---|
| Most funded longevity biotech startup | Altos Labs, with $3.0B raised |
| Second most funded longevity biotech startup | Insilico Medicine, with $811M raised |
| Largest longevity biotech funding round | Altos Labs, $3.0B venture financing in January 2022 |
| Median funding | About $29M across the listed startups |
| Share of funding captured by the top 10 | About 82% of disclosed funding |
| Median time since last round | About 2.7 years, based on July 2026 |
| Startups that raised funding in the last 12 months | 25 startups |
| Active longevity biotech startups listed | 66 active companies |
| Longevity biotech IPO or public-stage companies | 8 companies |
| Longevity biotech acquisitions and shutdowns | 10 acquired companies and 3 shutdowns |
Top startups in the longevity biotech market ranked by total funding raised
Here is an updated table that ranks the top startups in the longevity biotech market based on the total amount of funding they have raised to date.
The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected.
| # | Startup | What They Do | Total Raised ($) | Total Rounds | Last Round Date | Last Round Amount ($) | Last Round Type | Key Investors | Current Stage | Confidence |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Altos Labs | Cellular rejuvenation therapies | $3.0B | 1 | January 2022 | $3.0B | Venture financing | Jeff Bezos, Yuri Milner-linked capital, ARCH Venture Partners | Active | Full |
| 2 | Insilico Medicine | AI drug discovery | $811M | 6 | December 2025 | $293M | IPO | Value Partners, Warburg Pincus, Qiming Venture Partners | IPO | Partial |
| 3 | BioSplice Therapeutics | Alternative splicing therapeutics | $778M | 3 | April 2021 | $120M | Equity financing | Eventide, aMoon, SymBiosis II | Active | Strong |
| 4 | NewLimit | Epigenetic cell reprogramming | $715M | 4 | June 2026 | $435M | Series C | Founders Fund, Thrive Capital, Greenoaks | Active | Strong |
| 5 | BioAge Labs | Metabolic aging therapeutics | $492M | 5 | September 2024 | $198M | IPO | Sofinnova Investments, Andreessen Horowitz, Elad Gil | IPO | Strong |
| 6 | Celularity | Placenta-derived cell therapies | $408M | 6 | October 2025 | $2M | Preferred private placement | Celgene, United Therapeutics, Dragasac | IPO | Partial |
| 7 | Human Longevity | Genomics health intelligence | $330M | 4 | Undisclosed 2024 | Undisclosed | Equity investment | Celgene, Illumina, TVM Capital Healthcare | Active | Partial |
| 8 | Unity Biotechnology | Senolytic aging therapies | $297M | 4 | May 2018 | $85M | IPO | ARCH Venture Partners, Fidelity, EcoR1 Capital | Shutdown | Partial |
| 9 | Loyal | Dog longevity medicines | $250M | 6 | February 2026 | $100M | Series C | age1, Baillie Gifford, Bain Capital Ventures | Active | Partial |
| 10 | Life Biosciences | Cellular rejuvenation therapies | $237M | 4 | April 2026 | $80M | Series D | Alpha Wave Ventures, LeFrak, Abundance Partners | Active | Strong |
| 11 | Proteostasis Therapeutics | Protein-homeostasis therapeutics | $235M | 6 | October 2018 | $74M | Public equity offering | Cormorant, NEA, Novartis Venture Fund | Acquired | Strong |
| 12 | Nura Bio | Neuroprotective SARM1 inhibitors | $215M | 3 | June 2026 | $74M | Series B | The Column Group, Euclidean Capital, Sanofi Ventures | Active | Full |
| 13 | Retro Biosciences | Healthspan extension therapeutics | $180M | 1 | April 2022 | $180M | Seed | Sam Altman | Active | Partial |
| 14 | Juvenescence | Longevity drug portfolio | $165M | 3 | August 2019 | $100M | Series B | Grok Ventures, IPGL, founders | Active | Partial |
| 15 | resTORbio | Aging-related mTOR therapeutics | $163M | 3 | January 2018 | $98M | IPO | OrbiMed, Fidelity, PureTech | Acquired | Full |
| 16 | Cambrian Bio | Healthspan biotech portfolio | $160M | 2 | October 2021 | $100M | Series C | Anthos Capital, SALT Fund, Apeiron Investment Group | Active | Full |
| 17 | Alzheon | Alzheimer’s oral therapeutics | $160M | 4 | June 2024 | $100M | Series E | Alerce Medical Technology Partners, Ally Bridge Group | Active | Partial |
| 18 | Syntara | ECM-dysfunction drug development | $151M | 8 | June 2026 | $6M | Placement / SPP | Institutional investors, sophisticated investors, eligible shareholders | IPO | Partial |
| 19 | Aeovian Pharmaceuticals | Selective mTORC1 inhibitors | $142M | 3 | December 2025 | $55M | Series B | Luma Group, CTI Life Sciences, Hevolution | Active | Full |
| 20 | Longeveron | Regenerative cell therapies | $96M | 8 | March 2026 | $15M | Private placement | Coastlands Capital, Janus Henderson Investors, Logos Capital | IPO | Strong |
| 21 | Juvena Therapeutics | AI regenerative biologics | $84M | 3 | January 2026 | $34M | Series B | Bison Ventures, Eli Lilly, Jefferson Life Sciences | Active | Strong |
| 22 | Rejuveron Life Sciences | Healthy-aging therapeutics platform | $76M | 2 | September 2023 | $75M | Series B / convertible loan | Catalio, Apeiron, Mubadala Capital | Active | Partial |
| 23 | Navitor Pharmaceuticals | mTORC1-targeted therapeutics | $72M | 3 | April 2020 | $15M | Series D preferred equity | Supernus, Brace Pharma, Polaris Partners | Acquired | Strong |
| 24 | Elevian | Regenerative GDF11 medicines | $61M | 3 | September 2021 | $40M | Series A | Prime Movers Lab, Bold Capital, Kizoo Ventures | Active | Full |
| 25 | Gordian Biotechnology | In vivo aging drug discovery | $60M | 1 | April 2024 | $60M | Venture / raised to date | The Longevity Fund, Founders Fund, Gigafund | Active | Partial |
| 26 | CohBar | Mitochondrial peptide therapeutics | $59M | 5 | Undisclosed 2023 | $15M | Merger-linked PIPE | Public investors, Morphogenesis affiliate, Cantor Fitzgerald | Acquired | Partial |
| 27 | Retrotope | Neurodegenerative disease therapeutics | $59M | 7 | January 2021 | Undisclosed | Series D | SDL Ventures, MP Advisors, North Texas Angel Network | Acquired | Partial |
| 28 | Rubedo Life Sciences | Senescent-cell therapies for aging | $52M | 2 | April 2024 | $40M | Series A | Khosla Ventures, Ahren Innovation Capital, Hevolution | Active | Full |
| 29 | Spring Discovery | AI aging drug discovery | $48M | 2 | Undisclosed | $30M | Undisclosed equity | First Round, General Catalyst, Caffeinated Capital | Acquired | Partial |
| 30 | Arda Therapeutics | Targeted pathogenic cell depletion | $43M | 1 | October 2024 | $43M | Series A | a16z Bio + Health, Two Sigma Ventures, Eli Lilly | Active | Full |
| 31 | Mitotech | Mitochondria-targeted small molecules | $43M | 1 | Undisclosed | $43M | Undisclosed funding | Not disclosed | Active | Low |
| 32 | Alkahest | Plasma-proteome aging therapies | $41M | 2 | March 2015 | $38M | Strategic equity | Grifols, Nan Fung Life Sciences | Acquired | Strong |
| 33 | Amplifier Therapeutics | AMPK activators for aging diseases | $38M | 3 | October 2023 | $33M | Series A | Cambrian Bio, RA Capital Management, Future Ventures | Active | Partial |
| 34 | Jocasta Neuroscience | Klotho cognitive decline therapy | $35M | 1 | August 2025 | $35M | Series A | True Ventures, Moore Strategic Ventures, SC8 Investments | Active | Full |
| 35 | Tolerance Bio | Thymus immune tolerance therapies | $35M | 2 | June 2026 | $15M | Series A | Columbus Venture Partners, Criteria Bio Ventures, Beyond Celiac Investments | Active | Strong |
| 36 | Gero | AI aging drug discovery | $34M | 5 | June 2026 | $17M | New financing | Melnichek Investments, Bulba Ventures | Active | Partial |
| 37 | Sierra Sciences | Telomere aging research | $33M | Unknown | Undisclosed | Undisclosed | Undisclosed equity | Not disclosed | Active | Low |
| 38 | MindImmune Therapeutics | Neuroinflammation Alzheimer’s therapeutics | $31M | 3 | November 2025 | $18M | Series A extension | Dolby Family Ventures, Pfizer Ventures, Gates Frontier | Active | Strong |
| 39 | Turn Biotechnologies | mRNA epigenetic cell rejuvenation | $30M | 4 | September 2023 | $29M | Series A | Khosla Ventures, Astellas Venture Management, Daewoong Pharmaceutical | Active | Partial |
| 40 | Shift Bioscience | AI cell rejuvenation discovery | $29M | 7 | October 2024 | $16M | Seed | BGF, F-Prime Capital, Kindred Capital | Active | Partial |
| 41 | Samsara Therapeutics | Autophagy drugs for neurodegeneration | $28M | 3 | Undisclosed 2021 | $25M | Series A | Apollo Health Ventures | Active | Partial |
| 42 | Repair Biotechnologies | Cholesterol-degrading aging therapies | $26M | 8 | November 2025 | $5M | Series A | Jim Mellon, LongevityTech.fund, Thynk Capital | Active | Partial |
| 43 | Cyclarity Therapeutics | Toxic cholesterol disease therapies | $24M | 4 | December 2024 | $6M | Series A tranche | Ki Tua Fund, Kizoo, Formic Ventures | Active | Strong |
| 44 | LyGenesis | Lymph-node organ regeneration | $22M | 2 | October 2023 | $19M | Series A-2 | Prime Movers Lab, Juvenescence | Active | Strong |
| 45 | Rejuvenate Biomed | Sarcopenia drug development | $22M | 2 | October 2021 | $18M | Series B | Rejuveron Life Sciences, Vesalius Biocapital, JLABS | Active | Strong |
| 46 | Junevity | siRNA cell reprogramming therapies | $20M | 2 | December 2025 | $10M | Seed extension | Goldcrest Capital, Godfrey Capital | Active | Full |
| 47 | AgeX Therapeutics | Regenerative therapeutics for aging diseases | $20M | 3 | March 2019 | $5M | Post-IPO Equity | Juvenescence, BioTime-related investors | Acquired | Strong |
| 48 | Deciduous Therapeutics | Senescent-cell immune therapies | $17M | 2 | December 2022 | $10M | Seed | Owl Capital Group, Bold Capital Partners, Humboldt Fund | Active | Partial |
| 49 | Rejuvenate Bio | Age-related gene therapies | $16M | 2 | June 2026 | $6M | Financing | VCapital, Merck Animal Health, Digitalis | Active | Strong |
| 50 | Longevica | Longevity therapeutics platform | $16M | 3 | August 2022 | $0M | SAFE | Xploration Capital, Rostock Group, Foundation Venture Capital Group | Acquired | Partial |
| 51 | Chronos Therapeutics | Neuropsychiatry drug assets | $16M | 2 | December 2013 | $13M | Series B | University of Oxford, Vulpes Investment Management, Odey funds | Acquired | Strong |
| 52 | Oisin Biotechnologies | Genetic senolytic aging therapies | $15M | 1 | July 2024 | $15M | Series A | AbbVie Ventures, Althea Group, Healthspan Capital | Active | Low |
| 53 | Booster Therapeutics | Proteasome activator medicines | $15M | 1 | October 2024 | $15M | Seed | Apollo Health Ventures, Novo Holdings, Korify Capital | Active | Full |
| 54 | Generation Lab | Biological aging diagnostics | $15M | 2 | October 2025 | $11M | Seed | Accel, Samsung Next, Aoki Labs | Active | Strong |
| 55 | GlycanAge | Glycan biological age testing | $13M | 2 | December 2025 | $9M | Series A | Fifth Quarter Ventures, Guinness Ventures, BrightCap Ventures | Active | Strong |
| 56 | Morphoceuticals | Bioelectric tissue regeneration | $13M | 2 | September 2024 | $4M | Seed | Prime Movers Lab, Juvenescence | Active | Partial |
| 57 | MitoRx Therapeutics | Mitochondrial metabolic therapeutics | $12M | 3 | November 2025 | $7M | Pre-Series A | Oshen Holdings, UKI2S, Wren Capital | Active | Strong |
| 58 | Circulate Health | Therapeutic plasma exchange longevity | $12M | 1 | July 2025 | $12M | Seed | Khosla Ventures, Seaside Ventures, CSC Ventures | Active | Full |
| 59 | Edifice Health | Inflammatory healthspan diagnostics | $12M | 1 | March 2021 | $12M | Seed | Human Longevity, Longevity Incubator Fund, Better Food Ventures | Active | Strong |
| 60 | Epiterna | Aging-focused drug discovery | $11M | 1 | August 2023 | $11M | Seed | Prima Materia | Active | Strong |
| 61 | Rejuvenation Technologies | Telomere-extending mRNA therapeutics | $11M | 1 | September 2023 | $11M | Seed | Khosla Ventures, Shanda Ventures, Y Combinator | Active | Partial |
| 62 | NaNotics | Subtractive nanoparticle therapeutics | $10M | 3 | September 2024 | Undisclosed | Accelerator / Incubator | LifeSpan Vision Ventures, Lauder Partners, Melnichek Investments | Active | Partial |
| 63 | Tally Health | Biological age testing platform | $10M | 1 | April 2023 | $10M | Seed | Forerunner Ventures, L Catterton, G9 Ventures | Active | Full |
| 64 | FoxBio | Small-molecule senolytic drugs | $10M | 1 | July 2018 | $10M | JV equity financing | Juvenescence, Antoxerene, Kizoo | Active | Partial |
| 65 | clock.bio | Stem-cell rejuvenation therapeutics | $9M | 2 | October 2024 | $5M | Seed | LocalGlobe, BlueYard Capital, Onsight Ventures | Active | Strong |
| 66 | SENISCA | RNA senotherapeutics for aging diseases | $9M | 3 | March 2024 | $5M | Seed / pre-Series A | Lifespan Vision Ventures, Emerging Longevity Ventures, QantX | Active | Strong |
| 67 | AgelessRx | Longevity telehealth platform | $8M | 2 | March 2026 | $5M | Equity / Seed-Series A | Not publicly disclosed | Active | Partial |
| 68 | Genflow Biosciences | SIRT6 gene therapies for aging | $8M | 5 | May 2026 | $0M | Warrant exercise / Post-IPO Equity | Eric Leire, Gad Berdugo, Premier Miton | IPO | Strong |
| 69 | Revel Pharmaceuticals | Enzyme repair therapies | $8M | 1 | March 2022 | $8M | Seed | Kizoo Technology Capital, Starbloom Capital, Tubus LLC | Active | Strong |
| 70 | Thymmune Therapeutics | Thymic cell therapies | $7M | 1 | March 2023 | $7M | Seed | Pillar VC, NYBC Ventures | Active | Full |
| 71 | Matter Bio | Genomic integrity longevity therapeutics | $7M | 1 | May 2024 | $7M | Seed | Lifespan Vision Ventures, quadraScope Ventures | Active | Full |
| 72 | Vasa Therapeutics | Cardiovascular aging therapeutics | $6M | 1 | January 2024 | $6M | Seed | Orphinic Scientific, NuFund Venture Group, SeedFolio | Active | Full |
| 73 | NADMED | NAD metabolite diagnostics | $4M | 2 | August 2024 | $4M | Series A | Nordic Science Investments, Voima Ventures, University of Helsinki Funds | Active | Strong |
| 74 | Everon Biosciences | Anti-aging small-molecule therapeutics | $4M | 1 | Undisclosed | $4M | Undisclosed Private Financing | Skolkovo Foundation | Active | Low |
| 75 | Reservoir Neuroscience | Brain vascular therapeutics | $4M | 1 | November 2023 | $4M | Seed | Kizoo, R42 Group | Active | Full |
| 76 | Ichor Therapeutics | Aging-focused CRO and therapeutics | $3M | 6 | September 2022 | $0M | Seed Extension | Kizoo, Methuselah Foundation, Roger Bagg | Active | Partial |
| 77 | Gerostate Alpha | Drugs for aging diseases | $3M | 2 | November 2021 | $1M | Equity Crowdfunding / SAFE | Y Combinator, Longevitytech.fund, Sand Hill Angels | Shutdown | Partial |
| 78 | Cleara Biotech | Senescence therapies for chronic disease | $3M | 2 | September 2022 | $3M | Seed | Apollo Health Ventures, Curie Capital, ROM Utrecht Region | Active | Strong |
| 79 | Life Length | Telomere diagnostics platform | $3M | 6 | January 2024 | $2M | Undisclosed / EIC-linked | EIC Fund, European Union, Carlos Genzor | Active | Partial |
| 80 | Lysoclear | Enzyme therapies for eye disease | $3M | 1 | March 2019 | $3M | Series A | Kizoo | Active | Strong |
| 81 | ImmuneAge Bio | Immune rejuvenation drug discovery | $2M | 2 | July 2024 | $2M | Seed | 1517 Fund, Jack O’Meara, Alberto Santagostino | Active | Strong |
| 82 | SIWA Therapeutics | Senescent-cell antibody therapeutics | $2M | 1 | May 2017 | $2M | Seed | Not disclosed | Active | Partial |
| 83 | Antoxerene | Senolytic small-molecule discovery | $2M | 1 | June 2017 | $2M | Seed | Kizoo, SENS Research Foundation | Shutdown | Strong |
| 84 | Auctus Biologics | Antibody mimetic scaffold therapeutics | $2M | 1 | September 2018 | $2M | Seed | Grapeseed.Bio | Active | Strong |
| 85 | Five Alarm Bio | Small molecules targeting aging | $1M | 2 | February 2023 | $1M | Series A / Early-stage | Cambridge Angels, o2h Ventures, SyndicateRoom | Active | Partial |
| 86 | Genescient | Genomics for aging therapeutics | $1M | 1 | Undisclosed | $1M | Undisclosed Private Financing | Undisclosed investors | Active | Low |
| 87 | BioViva | Gene therapies for cellular aging | $0M | 2 | April 2022 | $0M | Securities Financing | Undisclosed investor | Active | Partial |
Key funding trends in the longevity biotech market
Insights
- Altos Labs alone accounts for about 37% of all listed longevity biotech funding, which makes the market look much larger and more mature than the median startup suggests.
- The top 10 longevity biotech startups capture about 82% of disclosed funding, so capital is concentrated in a small group of platform companies and late-stage therapeutic programs.
- NewLimit’s $435M Series C is larger than the total funding of almost every company below BioAge Labs, showing strong investor appetite for epigenetic reprogramming.
- Recent funding is not evenly spread across the longevity biotech market. NewLimit, Life Biosciences, Nura Bio, and Aeovian represent most of the larger private rounds since late 2025.
- The median company on this list has raised only about $29M, which shows that longevity biotech is still broad at the formation stage and selective at scale-up.
- mTOR-related longevity biology remains a clear funding theme, with Life Biosciences, Aeovian Pharmaceuticals, resTORbio, and Navitor Pharmaceuticals together raising more than $600M.
- Diagnostics and biological age testing companies remain far smaller than therapeutic platforms, with Tally Health, GlycanAge, NADMED, and Generation Lab all staying below $15M each.
- Public-market outcomes remain mixed in longevity biotech, as BioAge Labs and Longeveron are still listed while resTORbio, Proteostasis, Navitor, and AgeX ended through acquisitions.
A few word about our methodology
As you can see, we built a database that ranks longevity biotech startups based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.
Whenever possible, we prioritized official company communications, since official announcements are usually the most reliable source for funding amounts. When official sources were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times, Forbes, Fierce Biotech, Endpoints News, Longevity.Technology, or company filings.
We excluded random blogs, unverified websites, and any sources that could not be validated.
When longevity biotech funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.
Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.
Here is what they mean.
Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.
Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.
Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.
Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.
When the confidence level is too low, we take a conservative approach and may exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.
This reflects how we conduct all our research on the longevity biotech market.
In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.
If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.
Finally, know that we update the dataset once per month, so come back here if you need fresh information.
Related blog posts
- What are the latest fundraising trends in the longevity biotech market?
- Which companies are the most valued in the longevity biotech market?
- Is fundraising strong in the longevity biotech market right now?
- A full list of funding deals in the longevity biotech market
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