Which startups have raised the most funding in the longevity biotech market?

Last updated: 13 July 2026

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This article tracks the most funded startups in the longevity biotech market, ranked by cumulative funding raised.

We update this list every month, because longevity biotech funding changes quickly across private rounds, IPOs, acquisitions, and public-market financings.

The market is highly concentrated, with Altos Labs, Insilico Medicine, BioSplice Therapeutics, NewLimit, and BioAge Labs representing a large share of disclosed capital.

A quick summary table

Metric Value
Most funded longevity biotech startup Altos Labs, with $3.0B raised
Second most funded longevity biotech startup Insilico Medicine, with $811M raised
Largest longevity biotech funding round Altos Labs, $3.0B venture financing in January 2022
Median funding About $29M across the listed startups
Share of funding captured by the top 10 About 82% of disclosed funding
Median time since last round About 2.7 years, based on July 2026
Startups that raised funding in the last 12 months 25 startups
Active longevity biotech startups listed 66 active companies
Longevity biotech IPO or public-stage companies 8 companies
Longevity biotech acquisitions and shutdowns 10 acquired companies and 3 shutdowns

Top startups in the longevity biotech market ranked by total funding raised

Here is an updated table that ranks the top startups in the longevity biotech market based on the total amount of funding they have raised to date.

The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected.

# Startup What They Do Total Raised ($) Total Rounds Last Round Date Last Round Amount ($) Last Round Type Key Investors Current Stage Confidence
1 Altos Labs Cellular rejuvenation therapies $3.0B 1 January 2022 $3.0B Venture financing Jeff Bezos, Yuri Milner-linked capital, ARCH Venture Partners Active Full
2 Insilico Medicine AI drug discovery $811M 6 December 2025 $293M IPO Value Partners, Warburg Pincus, Qiming Venture Partners IPO Partial
3 BioSplice Therapeutics Alternative splicing therapeutics $778M 3 April 2021 $120M Equity financing Eventide, aMoon, SymBiosis II Active Strong
4 NewLimit Epigenetic cell reprogramming $715M 4 June 2026 $435M Series C Founders Fund, Thrive Capital, Greenoaks Active Strong
5 BioAge Labs Metabolic aging therapeutics $492M 5 September 2024 $198M IPO Sofinnova Investments, Andreessen Horowitz, Elad Gil IPO Strong
6 Celularity Placenta-derived cell therapies $408M 6 October 2025 $2M Preferred private placement Celgene, United Therapeutics, Dragasac IPO Partial
7 Human Longevity Genomics health intelligence $330M 4 Undisclosed 2024 Undisclosed Equity investment Celgene, Illumina, TVM Capital Healthcare Active Partial
8 Unity Biotechnology Senolytic aging therapies $297M 4 May 2018 $85M IPO ARCH Venture Partners, Fidelity, EcoR1 Capital Shutdown Partial
9 Loyal Dog longevity medicines $250M 6 February 2026 $100M Series C age1, Baillie Gifford, Bain Capital Ventures Active Partial
10 Life Biosciences Cellular rejuvenation therapies $237M 4 April 2026 $80M Series D Alpha Wave Ventures, LeFrak, Abundance Partners Active Strong
11 Proteostasis Therapeutics Protein-homeostasis therapeutics $235M 6 October 2018 $74M Public equity offering Cormorant, NEA, Novartis Venture Fund Acquired Strong
12 Nura Bio Neuroprotective SARM1 inhibitors $215M 3 June 2026 $74M Series B The Column Group, Euclidean Capital, Sanofi Ventures Active Full
13 Retro Biosciences Healthspan extension therapeutics $180M 1 April 2022 $180M Seed Sam Altman Active Partial
14 Juvenescence Longevity drug portfolio $165M 3 August 2019 $100M Series B Grok Ventures, IPGL, founders Active Partial
15 resTORbio Aging-related mTOR therapeutics $163M 3 January 2018 $98M IPO OrbiMed, Fidelity, PureTech Acquired Full
16 Cambrian Bio Healthspan biotech portfolio $160M 2 October 2021 $100M Series C Anthos Capital, SALT Fund, Apeiron Investment Group Active Full
17 Alzheon Alzheimer’s oral therapeutics $160M 4 June 2024 $100M Series E Alerce Medical Technology Partners, Ally Bridge Group Active Partial
18 Syntara ECM-dysfunction drug development $151M 8 June 2026 $6M Placement / SPP Institutional investors, sophisticated investors, eligible shareholders IPO Partial
19 Aeovian Pharmaceuticals Selective mTORC1 inhibitors $142M 3 December 2025 $55M Series B Luma Group, CTI Life Sciences, Hevolution Active Full
20 Longeveron Regenerative cell therapies $96M 8 March 2026 $15M Private placement Coastlands Capital, Janus Henderson Investors, Logos Capital IPO Strong
21 Juvena Therapeutics AI regenerative biologics $84M 3 January 2026 $34M Series B Bison Ventures, Eli Lilly, Jefferson Life Sciences Active Strong
22 Rejuveron Life Sciences Healthy-aging therapeutics platform $76M 2 September 2023 $75M Series B / convertible loan Catalio, Apeiron, Mubadala Capital Active Partial
23 Navitor Pharmaceuticals mTORC1-targeted therapeutics $72M 3 April 2020 $15M Series D preferred equity Supernus, Brace Pharma, Polaris Partners Acquired Strong
24 Elevian Regenerative GDF11 medicines $61M 3 September 2021 $40M Series A Prime Movers Lab, Bold Capital, Kizoo Ventures Active Full
25 Gordian Biotechnology In vivo aging drug discovery $60M 1 April 2024 $60M Venture / raised to date The Longevity Fund, Founders Fund, Gigafund Active Partial
26 CohBar Mitochondrial peptide therapeutics $59M 5 Undisclosed 2023 $15M Merger-linked PIPE Public investors, Morphogenesis affiliate, Cantor Fitzgerald Acquired Partial
27 Retrotope Neurodegenerative disease therapeutics $59M 7 January 2021 Undisclosed Series D SDL Ventures, MP Advisors, North Texas Angel Network Acquired Partial
28 Rubedo Life Sciences Senescent-cell therapies for aging $52M 2 April 2024 $40M Series A Khosla Ventures, Ahren Innovation Capital, Hevolution Active Full
29 Spring Discovery AI aging drug discovery $48M 2 Undisclosed $30M Undisclosed equity First Round, General Catalyst, Caffeinated Capital Acquired Partial
30 Arda Therapeutics Targeted pathogenic cell depletion $43M 1 October 2024 $43M Series A a16z Bio + Health, Two Sigma Ventures, Eli Lilly Active Full
31 Mitotech Mitochondria-targeted small molecules $43M 1 Undisclosed $43M Undisclosed funding Not disclosed Active Low
32 Alkahest Plasma-proteome aging therapies $41M 2 March 2015 $38M Strategic equity Grifols, Nan Fung Life Sciences Acquired Strong
33 Amplifier Therapeutics AMPK activators for aging diseases $38M 3 October 2023 $33M Series A Cambrian Bio, RA Capital Management, Future Ventures Active Partial
34 Jocasta Neuroscience Klotho cognitive decline therapy $35M 1 August 2025 $35M Series A True Ventures, Moore Strategic Ventures, SC8 Investments Active Full
35 Tolerance Bio Thymus immune tolerance therapies $35M 2 June 2026 $15M Series A Columbus Venture Partners, Criteria Bio Ventures, Beyond Celiac Investments Active Strong
36 Gero AI aging drug discovery $34M 5 June 2026 $17M New financing Melnichek Investments, Bulba Ventures Active Partial
37 Sierra Sciences Telomere aging research $33M Unknown Undisclosed Undisclosed Undisclosed equity Not disclosed Active Low
38 MindImmune Therapeutics Neuroinflammation Alzheimer’s therapeutics $31M 3 November 2025 $18M Series A extension Dolby Family Ventures, Pfizer Ventures, Gates Frontier Active Strong
39 Turn Biotechnologies mRNA epigenetic cell rejuvenation $30M 4 September 2023 $29M Series A Khosla Ventures, Astellas Venture Management, Daewoong Pharmaceutical Active Partial
40 Shift Bioscience AI cell rejuvenation discovery $29M 7 October 2024 $16M Seed BGF, F-Prime Capital, Kindred Capital Active Partial
41 Samsara Therapeutics Autophagy drugs for neurodegeneration $28M 3 Undisclosed 2021 $25M Series A Apollo Health Ventures Active Partial
42 Repair Biotechnologies Cholesterol-degrading aging therapies $26M 8 November 2025 $5M Series A Jim Mellon, LongevityTech.fund, Thynk Capital Active Partial
43 Cyclarity Therapeutics Toxic cholesterol disease therapies $24M 4 December 2024 $6M Series A tranche Ki Tua Fund, Kizoo, Formic Ventures Active Strong
44 LyGenesis Lymph-node organ regeneration $22M 2 October 2023 $19M Series A-2 Prime Movers Lab, Juvenescence Active Strong
45 Rejuvenate Biomed Sarcopenia drug development $22M 2 October 2021 $18M Series B Rejuveron Life Sciences, Vesalius Biocapital, JLABS Active Strong
46 Junevity siRNA cell reprogramming therapies $20M 2 December 2025 $10M Seed extension Goldcrest Capital, Godfrey Capital Active Full
47 AgeX Therapeutics Regenerative therapeutics for aging diseases $20M 3 March 2019 $5M Post-IPO Equity Juvenescence, BioTime-related investors Acquired Strong
48 Deciduous Therapeutics Senescent-cell immune therapies $17M 2 December 2022 $10M Seed Owl Capital Group, Bold Capital Partners, Humboldt Fund Active Partial
49 Rejuvenate Bio Age-related gene therapies $16M 2 June 2026 $6M Financing VCapital, Merck Animal Health, Digitalis Active Strong
50 Longevica Longevity therapeutics platform $16M 3 August 2022 $0M SAFE Xploration Capital, Rostock Group, Foundation Venture Capital Group Acquired Partial
51 Chronos Therapeutics Neuropsychiatry drug assets $16M 2 December 2013 $13M Series B University of Oxford, Vulpes Investment Management, Odey funds Acquired Strong
52 Oisin Biotechnologies Genetic senolytic aging therapies $15M 1 July 2024 $15M Series A AbbVie Ventures, Althea Group, Healthspan Capital Active Low
53 Booster Therapeutics Proteasome activator medicines $15M 1 October 2024 $15M Seed Apollo Health Ventures, Novo Holdings, Korify Capital Active Full
54 Generation Lab Biological aging diagnostics $15M 2 October 2025 $11M Seed Accel, Samsung Next, Aoki Labs Active Strong
55 GlycanAge Glycan biological age testing $13M 2 December 2025 $9M Series A Fifth Quarter Ventures, Guinness Ventures, BrightCap Ventures Active Strong
56 Morphoceuticals Bioelectric tissue regeneration $13M 2 September 2024 $4M Seed Prime Movers Lab, Juvenescence Active Partial
57 MitoRx Therapeutics Mitochondrial metabolic therapeutics $12M 3 November 2025 $7M Pre-Series A Oshen Holdings, UKI2S, Wren Capital Active Strong
58 Circulate Health Therapeutic plasma exchange longevity $12M 1 July 2025 $12M Seed Khosla Ventures, Seaside Ventures, CSC Ventures Active Full
59 Edifice Health Inflammatory healthspan diagnostics $12M 1 March 2021 $12M Seed Human Longevity, Longevity Incubator Fund, Better Food Ventures Active Strong
60 Epiterna Aging-focused drug discovery $11M 1 August 2023 $11M Seed Prima Materia Active Strong
61 Rejuvenation Technologies Telomere-extending mRNA therapeutics $11M 1 September 2023 $11M Seed Khosla Ventures, Shanda Ventures, Y Combinator Active Partial
62 NaNotics Subtractive nanoparticle therapeutics $10M 3 September 2024 Undisclosed Accelerator / Incubator LifeSpan Vision Ventures, Lauder Partners, Melnichek Investments Active Partial
63 Tally Health Biological age testing platform $10M 1 April 2023 $10M Seed Forerunner Ventures, L Catterton, G9 Ventures Active Full
64 FoxBio Small-molecule senolytic drugs $10M 1 July 2018 $10M JV equity financing Juvenescence, Antoxerene, Kizoo Active Partial
65 clock.bio Stem-cell rejuvenation therapeutics $9M 2 October 2024 $5M Seed LocalGlobe, BlueYard Capital, Onsight Ventures Active Strong
66 SENISCA RNA senotherapeutics for aging diseases $9M 3 March 2024 $5M Seed / pre-Series A Lifespan Vision Ventures, Emerging Longevity Ventures, QantX Active Strong
67 AgelessRx Longevity telehealth platform $8M 2 March 2026 $5M Equity / Seed-Series A Not publicly disclosed Active Partial
68 Genflow Biosciences SIRT6 gene therapies for aging $8M 5 May 2026 $0M Warrant exercise / Post-IPO Equity Eric Leire, Gad Berdugo, Premier Miton IPO Strong
69 Revel Pharmaceuticals Enzyme repair therapies $8M 1 March 2022 $8M Seed Kizoo Technology Capital, Starbloom Capital, Tubus LLC Active Strong
70 Thymmune Therapeutics Thymic cell therapies $7M 1 March 2023 $7M Seed Pillar VC, NYBC Ventures Active Full
71 Matter Bio Genomic integrity longevity therapeutics $7M 1 May 2024 $7M Seed Lifespan Vision Ventures, quadraScope Ventures Active Full
72 Vasa Therapeutics Cardiovascular aging therapeutics $6M 1 January 2024 $6M Seed Orphinic Scientific, NuFund Venture Group, SeedFolio Active Full
73 NADMED NAD metabolite diagnostics $4M 2 August 2024 $4M Series A Nordic Science Investments, Voima Ventures, University of Helsinki Funds Active Strong
74 Everon Biosciences Anti-aging small-molecule therapeutics $4M 1 Undisclosed $4M Undisclosed Private Financing Skolkovo Foundation Active Low
75 Reservoir Neuroscience Brain vascular therapeutics $4M 1 November 2023 $4M Seed Kizoo, R42 Group Active Full
76 Ichor Therapeutics Aging-focused CRO and therapeutics $3M 6 September 2022 $0M Seed Extension Kizoo, Methuselah Foundation, Roger Bagg Active Partial
77 Gerostate Alpha Drugs for aging diseases $3M 2 November 2021 $1M Equity Crowdfunding / SAFE Y Combinator, Longevitytech.fund, Sand Hill Angels Shutdown Partial
78 Cleara Biotech Senescence therapies for chronic disease $3M 2 September 2022 $3M Seed Apollo Health Ventures, Curie Capital, ROM Utrecht Region Active Strong
79 Life Length Telomere diagnostics platform $3M 6 January 2024 $2M Undisclosed / EIC-linked EIC Fund, European Union, Carlos Genzor Active Partial
80 Lysoclear Enzyme therapies for eye disease $3M 1 March 2019 $3M Series A Kizoo Active Strong
81 ImmuneAge Bio Immune rejuvenation drug discovery $2M 2 July 2024 $2M Seed 1517 Fund, Jack O’Meara, Alberto Santagostino Active Strong
82 SIWA Therapeutics Senescent-cell antibody therapeutics $2M 1 May 2017 $2M Seed Not disclosed Active Partial
83 Antoxerene Senolytic small-molecule discovery $2M 1 June 2017 $2M Seed Kizoo, SENS Research Foundation Shutdown Strong
84 Auctus Biologics Antibody mimetic scaffold therapeutics $2M 1 September 2018 $2M Seed Grapeseed.Bio Active Strong
85 Five Alarm Bio Small molecules targeting aging $1M 2 February 2023 $1M Series A / Early-stage Cambridge Angels, o2h Ventures, SyndicateRoom Active Partial
86 Genescient Genomics for aging therapeutics $1M 1 Undisclosed $1M Undisclosed Private Financing Undisclosed investors Active Low
87 BioViva Gene therapies for cellular aging $0M 2 April 2022 $0M Securities Financing Undisclosed investor Active Partial

Key funding trends in the longevity biotech market

Insights

  • Altos Labs alone accounts for about 37% of all listed longevity biotech funding, which makes the market look much larger and more mature than the median startup suggests.
  • The top 10 longevity biotech startups capture about 82% of disclosed funding, so capital is concentrated in a small group of platform companies and late-stage therapeutic programs.
  • NewLimit’s $435M Series C is larger than the total funding of almost every company below BioAge Labs, showing strong investor appetite for epigenetic reprogramming.
  • Recent funding is not evenly spread across the longevity biotech market. NewLimit, Life Biosciences, Nura Bio, and Aeovian represent most of the larger private rounds since late 2025.
  • The median company on this list has raised only about $29M, which shows that longevity biotech is still broad at the formation stage and selective at scale-up.
  • mTOR-related longevity biology remains a clear funding theme, with Life Biosciences, Aeovian Pharmaceuticals, resTORbio, and Navitor Pharmaceuticals together raising more than $600M.
  • Diagnostics and biological age testing companies remain far smaller than therapeutic platforms, with Tally Health, GlycanAge, NADMED, and Generation Lab all staying below $15M each.
  • Public-market outcomes remain mixed in longevity biotech, as BioAge Labs and Longeveron are still listed while resTORbio, Proteostasis, Navitor, and AgeX ended through acquisitions.

A few word about our methodology

As you can see, we built a database that ranks longevity biotech startups based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.

Whenever possible, we prioritized official company communications, since official announcements are usually the most reliable source for funding amounts. When official sources were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times, Forbes, Fierce Biotech, Endpoints News, Longevity.Technology, or company filings.

We excluded random blogs, unverified websites, and any sources that could not be validated.

When longevity biotech funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.

Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.

Here is what they mean.

Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.

Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.

Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.

Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.

When the confidence level is too low, we take a conservative approach and may exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.

This reflects how we conduct all our research on the longevity biotech market.

In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.

If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.

Finally, know that we update the dataset once per month, so come back here if you need fresh information.

Who is the author of this content?

NEW MARKET PITCH TEAM

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