Which startups have raised the most funding in the biotechnology market?

Last updated: 13 July 2026

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The biotechnology market is one of the deepest startup funding markets, with capital flowing into AI drug discovery, oncology, diagnostics, cell therapy, gene therapy, and next-generation platform biology.

This list ranks biotechnology startups by cumulative funding raised, and we update it every month to keep the dataset useful for investors, founders, and market researchers.

The ranking shows a market shaped by very large platform rounds, strong specialist investors, and public-market financing for clinical-stage companies.

And if you want to better understand this new industry, you can download our pitch covering the biotechnology market.

A quick summary table

Metric Value
Most funded startup Altos Labs, with $3.0B raised
Second most funded startup Isomorphic Labs, with $2.7B raised
Largest funding round Altos Labs, with a $3.0B launch round in January 2022
Median funding About $495M across the top 100 biotechnology startups
Share of funding captured by the top 10 About 36% of total funding in this ranking
Median time since last round About 2 years and 8 months, based on the listed last round dates
Startups that raised funding in the last 12 months 23 startups, based on rounds from July 2025 to June 2026
AI biotechnology startups above $1B Five major names: Isomorphic Labs, Eikon Therapeutics, Generate Biomedicines, Xaira Therapeutics, and XtalPi
Oncology biotechnology funding concentration At least 10 leading oncology-focused companies raised roughly $10B combined
Biotechnology IPO exposure IPO-stage companies represent a large share of the top 30 funded startups
Chart illustrating yearly venture capital funding for biotechnology startups

This chart, featured in our biotechnology market deck, illustrates yearly venture capital funding for biotechnology startups

Top startups in the biotechnology market ranked by total funding raised

Here is an updated table that ranks the top startups in the biotechnology market based on the total amount of funding they have raised to date.

The table also includes the total number of funding rounds, the date and size of the latest round, the financing type (e.g. Series A, equity financing), key investors, the startup’s current status (active, IPO, acquired, or shut down), and a confidence score based on the data collected (we excluded startups with very low data confidence, to make sure everything is reliable).

If you're interested in knowing how much these startups are worth, you can check our list of the top startups in the biotechnology market ranked by valuation.

# Startup What They Do Total Raised ($) Total Rounds Last Round Date Last Round Amount ($) Last Round Type Key Investors Current Stage Confidence
1 Altos Labs Cellular rejuvenation therapeutics research $3.0B 1 January 2022 $3.0B Launch / Seed Yuri Milner, Jeff Bezos, ARCH Venture Partners Active Strong
2 Isomorphic Labs AI drug discovery $2.7B 2 May 2026 $2.1B Series B Thrive Capital, Alphabet, GV Active Full
3 GRAIL Multi-cancer blood testing $2.4B 6 June 2026 $110M Strategic Equity Financing Samsung C&T, Samsung Electronics IPO Strong
4 Caris Life Sciences AI precision oncology profiling $1.9B 5 June 2025 $494M IPO Braidwell, OrbiMed, Coatue IPO Strong
5 Intarcia Therapeutics Implantable drug delivery $1.8B 19 August 2017 $525M Series J RA Capital, Venrock, Gates Foundation Acquired Partial
6 Kailera Therapeutics Obesity therapeutics $1.7B 3 April 2026 $719M IPO Atlas Venture, Bain Capital, RTW Investments IPO Full
7 MGI Tech Sequencing and multiomics platforms $1.7B 3 September 2022 $518M IPO IDG Capital, CPE, CITIC IPO Strong
8 FogPharma / Parabilis Medicines Helicon peptide cancer medicines $1.6B 8 June 2026 $75M Concurrent private placement Regeneron IPO Full
9 Eikon Therapeutics Protein-dynamics drug discovery $1.5B 5 February 2026 $381M IPO Public-market investors IPO Full
10 Freenome Multiomics cancer blood tests $1.3B 7 February 2024 $254M Series E Roche, a16z, existing investors Active Full
11 ElevateBio Cell and gene therapy platform $1.2B 4 May 2023 $401M Series D AyurMaya / Matrix, Woodline, Novo Nordisk Active Full
12 Abogen Biosciences mRNA vaccines and therapeutics $1.1B 5 May 2022 Undisclosed Series C extension SoftBank Vision Fund, 5Y Capital, Temasek Active Strong
13 Treeline Biosciences Precision oncology medicines $1.1B 4 September 2025 $200M Series A Extension ARCH Venture Partners, OrbiMed, KKR Active Partial
14 Generate Biomedicines AI protein therapeutics $1.1B 4 February 2026 $400M IPO Public investors IPO Full
15 Lyell Immunopharma CAR-T therapies for cancer $1.0B 5 March 2026 $50M Post-IPO private placement GSK, ARCH Venture Partners, Foresite Capital IPO Partial
16 Xaira Therapeutics AI drug discovery platform $1.0B 1 April 2024 $1.0B Series A ARCH Venture Partners, Foresite Capital, NEA Active Full
17 Odyssey Therapeutics Autoimmune precision medicines $979M 5 May 2026 $279M IPO OrbiMed, General Catalyst, Ascenta Capital IPO Strong
18 MapLight Therapeutics CNS disorder drug discovery $959M 5 October 2025 $296M IPO + private placement Forbion, Goldman Sachs Alternatives, Novo Holdings IPO Strong
19 CG Oncology Bladder cancer immunotherapy $936M 8 December 2024 $238M Follow-on offering Foresite Capital, TCGX, Longitude Capital IPO Full
20 Kriya Therapeutics Gene therapy platform $921M 5 September 2025 $320M Series D Patient Square Capital, Premji Invest, Narya Capital Active Strong
21 Invivyd Viral antibody therapies $863M 6 October 2025 $30M ATM equity issuance RA Capital, Janus Henderson, public investors IPO Strong
22 Neumora Therapeutics Precision brain disease medicines $862M 3 September 2023 $250M IPO ARCH Venture Partners, Amgen, Mubadala Capital IPO Full
23 XtalPi AI drug discovery $861M 4 June 2024 $127M IPO SoftBank Vision Fund, OrbiMed, Sequoia China IPO Partial
24 Everest Medicines Asia-focused biopharma commercialization $811M 3 October 2020 $451M IPO Public-market investors IPO Strong
25 Rakuten Medical Photoimmunotherapy cancer platform $757M 5 January 2026 $100M Series F TaiAx, Hikma, General Catalyst Active Partial
26 Shanghai Henlius Biotech Biologic medicines and biosimilars $757M 4 September 2019 $410M IPO Public investors, Fosun, Shenzhen GTJA Investment Group IPO Partial
27 Brii Biosciences Infectious disease therapies $734M 4 July 2021 $320M IPO Invesco, GIC, ARCH Venture Partners IPO Strong
28 RayzeBio Targeted radiopharmaceutical cancer drugs $708M 5 September 2023 $290M IPO Venrock, Viking Global, Wellington Management Acquired Full
29 Samsung Bioepis Biosimilar medicines developer $700M 2+ 2016 $345M Share issue Samsung Biologics, Biogen Acquired Low
30 Upstream Bio Inflammatory disease antibodies $693M 3 October 2024 $293M IPO OrbiMed, Maruho, Enavate Sciences IPO Full
31 Cellares Automated cell therapy manufacturing $682M 4 June 2026 $327M Series D BlackRock, Eclipse, Prime Radiant Partners Active Full
32 Element Biosciences DNA sequencing platforms $678M 5 July 2024 $277M Series D Wellington, Samsung, Venrock Active Full
33 Mirador Therapeutics Immunology precision medicines $650M 2 January 2026 $250M Series B ARCH Venture Partners, Fidelity, T. Rowe Price Active Strong
34 Insitro ML drug discovery $643M 3 March 2021 $400M Series C CPP Investments, Andreessen Horowitz, BlackRock Active Full
35 LianBio Asia-focused drug development $638M 3 November 2021 $325M IPO Perceptive Advisors, RA Capital, Venrock Shutdown Strong
36 Maze Therapeutics Genetics-based precision medicines $636M 4 January 2025 $140M IPO Third Rock Ventures, ARCH Venture Partners, Matrix Capital IPO Full
37 ArsenalBio Programmable cell therapies $630M 3 September 2024 $325M Series C ARCH Venture Partners, Regeneron Ventures, NVentures Active Full
38 Bicara Therapeutics Dual-action cancer biologics $628M 4 September 2024 $315M IPO Braidwell, TPG, RA Capital IPO Full
39 Tessera Therapeutics Gene writing genetic medicines $610M 3 April 2022 $300M Series C ADIA, Alaska Permanent Fund, T. Rowe Price Active Strong
40 Formation Bio AI-native drug development $608M 3 June 2024 $372M Series D a16z, Sanofi, Sequoia Active Partial
41 Ultima Genomics Low-cost genome sequencing $600M 1 May 2022 $600M Venture Financing General Atlantic, Andreessen Horowitz, Khosla Ventures Active Strong
42 Genor Biopharma Antibody oncology drugs $588M 3 October 2020 $372M IPO Public investors IPO Strong
43 ArriVent Biopharma Lung cancer therapeutics $555M 4 July 2025 $75M Public offering Sofinnova, General Catalyst, OrbiMed IPO Full
44 ACELYRIN Immunology drug development $550M 3 September 2022 $300M Series C Access Biotechnology, AyurMaya, Westlake Village BioPartners Acquired Strong
45 Harbour BioMed Antibody oncology therapeutics $543M 5 December 2020 $221M IPO BlackRock Fund, HBM Healthcare, Hillhouse Capital IPO Strong
46 Zenas BioPharma Immunology therapies $543M 3 September 2024 $225M IPO SR One, NEA, Enavate Sciences IPO Strong
47 Alumis Precision immunology oral therapies $529M 3 March 2024 $259M Series C Foresite Capital, Samsara BioCapital, venBio Partners IPO Full
48 Insilico Medicine Generative AI drug discovery $510M 5 March 2025 $110M Series E Value Partners, SPDB Group, Warburg Pincus Active Strong
49 Inscripta Genome engineering tools $502M 12 December 2022 $28M Later equity round Paladin Capital, Fidelity, T. Rowe Price Active Partial
50 Stemcentrx Cancer stem-cell ADCs $500M 4 August 2015 $250M Series G Founders Fund, Fidelity, ARTIS Ventures Acquired Partial
51 Laronde Endless RNA medicines $490M 2 August 2021 $440M Series B Flagship Pioneering, T. Rowe Price, BlackRock Acquired Full
52 Metagenomi Next-generation gene editing $460M 5 February 2024 $94M IPO Leaps by Bayer, Novo Holdings, PFM Health Sciences IPO Partial
53 Synthego CRISPR genome engineering tools $460M 7 February 2022 $200M Series E Perceptive Advisors, SoftBank Vision Fund 2, Wellington Management Acquired Strong
54 Genuity Science Genomic data analytics platform $455M 3 November 2018 $200M Series C ISIF, Temasek, Sequoia Capital Shutdown Partial
55 eGenesis Gene-edited transplant organs $454M 4 September 2024 $191M Series D Lux Capital, Khosla Ventures, existing investors Active Strong
56 TORL BioTherapeutics Antibody cancer therapies $450M 4 October 2025 $96M Series C Deep Track Capital, RA Capital, Perceptive Advisors Active Partial
57 Avenzo Therapeutics Oncology drug candidates $446M 4 September 2025 $60M Series B OrbiMed, SR One, Longwood Fund Active Partial
58 TauRx Pharmaceuticals Alzheimer’s tau-targeting therapies $434M 6 November 2022 $119M Warrant Exercise Existing shareholders, Dundee Corporation, GEM Asset Management Active Partial
59 Areteia Therapeutics Oral eosinophilic asthma therapy $425M 2 February 2024 $75M Series A extension Bain Capital Life Sciences, GV, ARCH Venture Partners Active Full
60 Apollo Therapeutics Portfolio biopharma drug development $422M 3 September 2023 $227M Series C Patient Square Capital, M&G plc, Rock Springs Capital Active Strong
61 Neurona Therapeutics Regenerative neural cell therapies $418M 9 April 2025 $102M Private financing Fidelity, The Column Group, Viking Global Investors Acquired Partial
62 Benchling Life sciences R&D cloud $412M 9 November 2021 $100M Series F Altimeter, Franklin Templeton, Tiger Global Active Strong
63 Valo Health AI drug discovery $400M 3 March 2021 $110M Series B Final Close Flagship Pioneering, PSP Investments, Koch Disruptive Technologies Active Partial
64 DNAnexus Cloud genomic data platform $390M 6 March 2022 $200M Series H Blackstone Growth, Northpond, GV Active Partial
65 Carmot Therapeutics Metabolic disease drug developer $386M 16 May 2023 $150M Series E Deep Track Capital, RA Capital, 5AM Ventures Acquired Partial
66 Haihe Biopharma Oncology drug developer $374M 4 September 2025 $42M Private Placement Deluxe Family Co. Active Partial
67 ReCode Therapeutics Genetic medicines delivery platform $371M 7 September 2025 $29M Additional financing Pfizer Ventures, EcoR1, OrbiMed Active Strong
68 Human Longevity AI longevity health platform $370M 4 August 2024 $40M Series B TVM Capital Healthcare, Panacea Venture, Emerging Technology Partners Active Partial
69 Thrive Earlier Detection Multi-cancer blood screening $367M 2 July 2020 $257M Series B Casdin Capital, Section 32, Bain Capital Life Sciences Acquired Full
70 AvenCell Switchable CAR-T therapies $362M 2 October 2024 $112M Series B Novo Holdings, F-Prime, Blackstone Life Sciences Active Full
71 ADARx Pharmaceuticals RNA-targeting therapeutics $353M 7 August 2023 $200M Series C Bain Capital Life Sciences, TCGX, BlackRock Active Partial
72 Helix Population genomics testing $350M 3 June 2021 $50M Series C Warburg Pincus, DFJ Growth, Temasek Active Partial
73 Thousand Oaks Biopharmaceuticals Biologics CDMO and media $346M 3 December 2021 $240M Growth Financing Goldstone Investment, CDH Investments, GL Ventures Active Strong
74 AltruBio Immune disease therapeutics $340M 7 May 2024 $225M Series B BVF Partners, RA Capital Management, Cormorant Asset Management Active Partial
75 Avistone Pharmaceuticals Precision oncology therapeutics $340M 2 January 2024 $140M Series B SDIC CS Capital, IDG Capital, Bain Capital Active Strong
76 Capstan Therapeutics In vivo cell engineering $340M 3 March 2024 $175M Series B RA Capital, Forbion, JJDC Acquired Full
77 DELFI Diagnostics Cancer liquid biopsy tests $332M 4 December 2025 Undisclosed Later equity financing Menlo Ventures, OrbiMed, DFJ Growth Active Strong
78 Forge Biologics Gene therapy CDMO $330M 4 September 2022 $90M Series C Drive Capital, Aisling Capital, strategic investor Acquired Strong
79 Obsidian Therapeutics Engineered cell therapies $325M 3 April 2024 $161M Series C Wellington Management, TCGX, GV Active Full
80 Karius Infectious disease diagnostics $320M 4 May 2024 $100M Series C Khosla Ventures, 5AM Ventures, Gilde Healthcare Active Strong
81 SOTIO Biotech Clinical immuno-oncology therapies $316M 1 December 2021 $316M Owner Funding PPF Group Active Strong
82 Chime Biologics Biologics CDMO services $315M 2 March 2021 $190M Series A+ VMS Group, Fidelity International, Panacea Venture Active Full
83 DNA Script Enzymatic DNA printing $315M 10 September 2023 $4M Later financing T. Rowe Price, Baillie Gifford, Casdin Capital Active Strong
84 Owkin AI biology research platform $304M 4+ November 2021 $180M Strategic equity Sanofi, Bpifrance, GV Active Partial
85 Normax Biomed mRNA vaccines manufacturing $303M 1 July 2022 $303M Share subscription facility Global Emerging Markets Active Low
86 Orna Therapeutics Circular RNA therapies $301M 2 August 2022 $221M Series B Merck, MPM Capital, BioImpact Capital Acquired Strong
87 ReNAgade Therapeutics RNA medicines platform $300M 1 May 2023 $300M Series A MPM BioImpact, F2 Ventures Acquired Full
88 Amolyt Pharma Rare endocrine peptide therapeutics $293M 3 January 2023 $138M Series C Sofinnova Partners, ICG, Novo Holdings Acquired Full
89 CardioDx Cardiovascular genomic diagnostics $282M 11 January 2017 $18M Later equity financing Longitude Capital, J.P. Morgan, Bright Capital Shutdown Partial
90 Vividion Therapeutics Undruggable target therapeutics $267M 3 February 2021 $135M Series C Logos Capital, Boxer Capital, ARCH Venture Partners Acquired Full
91 Senda Biosciences Programmable mRNA delivery medicines $266M 3 August 2022 $123M Series C Flagship Pioneering, Samsung Life Science Fund, Qatar Investment Authority Acquired Strong
92 Frontier Medicines Drugging undruggable proteins $256M 4 June 2024 $20M Series C Extension Deep Track Capital, ArrowMark Partners Active Full
93 Mojave Pharma Neuropsychiatric drug development $220M 1 October 2017 $220M Series C Not disclosed Shutdown Low
94 Shanghai Cell Therapy Group Cell therapy R&D services $211M 2 March 2021 $77M Series D CCB International, Haier Capital, Jiuzhou Venture Active Partial
95 GenapSys Portable DNA sequencing platform $206M 4 May 2021 $70M Series D Farallon Capital, Soleus Capital, PBM Capital Shutdown Partial
96 Castle Creek Biosciences Rare disease gene therapies $193M 4 May 2022 $113M Preferred stock Paragon Biosciences, Fidelity, Valor Equity Partners Active Partial
97 Beijing Biostar Technologies Synthetic biology cancer drugs $180M 3+ October 2024 $45M IPO Matrix Partners China, Efung Capital, CCB International IPO Partial
98 Botamedi Algae-derived therapeutics $159M 1 May 2018 $159M PE round Shining Sun Technology Active Low
99 3D Medicines Cancer immunotherapy medicines $140M 1 October 2020 $140M Private financing Efung Capital, China Capital Management, Ruiyi Investment IPO Partial
100 Voronoi Kinase inhibitor drugs $92M 3 June 2023 $35M Post-IPO Equity Nice Investment Partners, Honest Ventures, ES Investor IPO Low
Market map chart showing top companies and startups in the biotechnology market

This market map, featured in our biotechnology market deck, highlights top companies and startups in the biotechnology market

Key funding trends in the biotechnology market

Insights

  • The top 10 biotechnology startups raised about $19.5B combined, which shows how strongly capital is concentrated in platform biology, oncology, diagnostics, and AI drug discovery.
  • Altos Labs alone raised more than the bottom 17 companies combined, which shows how one exceptional launch round can reshape a biotechnology funding ranking.
  • AI drug discovery is now one of the deepest capital pools in biotechnology, with Isomorphic Labs, Generate Biomedicines, Insitro, Insilico Medicine, Xaira, and Eikon raising about $7.4B combined.
  • Oncology remains the strongest biotechnology funding theme, with GRAIL, Caris, FogPharma, Freenome, CG Oncology, Odyssey, ArsenalBio, Bicara, RayzeBio, and Zenas raising roughly $10.3B.
  • Cell and gene therapy platforms remain highly fundable, with ElevateBio, Cellares, ArsenalBio, Kriya, AvenCell, Capstan, and Chime Biologics raising about $4.2B in aggregate.
  • Diagnostics and sequencing companies show unusual scale for life sciences tools, with GRAIL, Caris, Freenome, Element Biosciences, MGI Tech, Ultima Genomics, Karius, DNA Script, and DELFI raising about $8.8B.
  • Several biotechnology companies crossed $1B with fewer than five rounds, which suggests investors are willing to fund compressed paths when the platform targets very large markets.
  • Recent mega-rounds in 2024, 2025, and 2026 show that late-stage biotechnology investors still back differentiated platforms, even in a more selective funding environment.
  • Specialist investors appear again and again near the top of the ranking, especially ARCH, OrbiMed, RA Capital, Foresite, Flagship, and Bain Capital Life Sciences.
  • Precision immunology is becoming a major biotechnology funding theme, with Alumis, Zenas, Mirador, Areteia, Apollo, and Odyssey together raising more than $4.0B.
Google Trends chart showing rising interest in biotech

As this chart shows, and as featured in our biotechnology market deck, search interest in biotech has been trending upward

A few word about our methodology

As you can see, we built a database that ranks startups in the biotechnology market based on their total cumulative fundraising. To create this ranking, we reviewed many sources and cross-checked information across multiple places.

Whenever possible, we prioritized official company communications, since they are the most reliable source for funding amounts. When those were not available, we relied on reputable industry sources such as TechCrunch, Crunchbase, Financial Times or Forbes (to name a few).

We excluded random blogs, unverified websites, and any sources that could not be validated.

When funding rounds were announced in other currencies such as euros, Swiss francs, Singapore dollars, Australian dollars, or rupees, we converted them into approximate USD equivalents for consistency.

Sometimes different sources report slightly different numbers, or the exact round size is not fully disclosed. In those cases, we flag the uncertainty and assign a confidence label to each startup, visible in the last column.

Here is what they mean.

Full confidence: The company’s equity fundraising history can be reconstructed completely from public sources. The rounds, dates, amounts, and key investors are clearly identified, with no meaningful gaps.

Strong confidence: The fundraising history is largely complete and reliable. There may be a small missing detail, such as incomplete investor information or a minor round with limited data, but the overall record is clear.

Partial confidence: The main fundraising rounds can be identified, but the record is incomplete or somewhat mixed. Some rounds may be missing or certain funding events may be difficult to separate clearly.

Low confidence: Public information is too limited, inconsistent, or ambiguous to reliably reconstruct the company’s equity fundraising history.

When the confidence level is too low, we take a conservative approach and exclude the company from the ranking. We don’t want to include data that cannot be reliably verified.

This reflects how we conduct all our research, including the work behind our report covering the biotechnology market.

In a world where LLMs hallucinate and unreliable information is everywhere, our goal is simple: provide data you can trust.

If you want the full detail on a specific calculation, feel free to contact us and we will gladly explain.

Finally, know that we update the dataset once per month, so come back here if you need fresh information.

Chart showing Vertex’s strategy in the biotechnology market

This chart, featured in our biotechnology market deck, looks at Vertex’s strategy in biotechnology

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